9KR6
Cryo-EM structure of MPXV core protease in complex with the substrate derivative I-G18
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | Core protease I7 | polymer | 423 | 49088.5 | 2 | UniProt (Q5IXV7) Pfam (PF03290) | Monkeypox virus | I7L,MPXV-COP-062,MPXV-SL-062,MPXV-WRAIR062,MPXVgp068,Viral core cysteine proteinase,Virion core cysteine protease |
| 2 | B, D (C, D) | Core protein VP8 | polymer | 10 | 1127.2 | 2 | UniProt (M1L511) | Monkeypox virus |
Sequence modifications
C, D: 0 - 9 (UniProt: M1L511)
| PDB | External Database | Details |
|---|---|---|
| Eta 9 | Gly 18 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 100431.4 | |
| All* | Total formula weight | 100431.4 |
