3QI3
 
 | | Crystal structure of PDE9A(Q453E) in complex with inhibitor BAY73-6691 | | Descriptor: | 1-(2-chlorophenyl)-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-1,7-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... | | Authors: | Hou, J, Xu, J, Liu, M, Zhao, R, Lou, H, Ke, H. | | Deposit date: | 2011-01-26 | | Release date: | 2011-04-27 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural asymmetry of phosphodiesterase-9, potential protonation of a glutamic Acid, and role of the invariant glutamine.
Plos One, 6, 2011
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1ZP0
 | | Crystal Structure of Mitochondrial Respiratory Complex II bound with 3-nitropropionate and 2-thenoyltrifluoroacetone | | Descriptor: | 3-NITROPROPANOIC ACID, 4,4,4-TRIFLUORO-1-THIEN-2-YLBUTANE-1,3-DIONE, FAD-binding protein, ... | | Authors: | Sun, F, Huo, X, Zhai, Y, Wang, A, Xu, J, Su, D, Bartlam, M, Rao, Z. | | Deposit date: | 2005-05-16 | | Release date: | 2005-07-12 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Crystal Structure of Mitochondrial Respiratory Membrane Protein Complex II
Cell(Cambridge,Mass.), 121, 2005
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1ZOY
 | | Crystal Structure of Mitochondrial Respiratory Complex II from porcine heart at 2.4 Angstroms | | Descriptor: | FAD-binding protein, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... | | Authors: | Sun, F, Huo, X, Zhai, Y, Wang, A, Xu, J, Su, D, Bartlam, M, Rao, Z. | | Deposit date: | 2005-05-15 | | Release date: | 2005-07-12 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal Structure of Mitochondrial Respiratory Membrane Protein Complex II
Cell(Cambridge,Mass.), 121, 2005
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1ZHU
 | | DNA (5'-D(*CP*AP*AP*TP*GP*CP*AP*AP*TP*G)-3'), NMR, 10 STRUCTURES | | Descriptor: | DNA (5'-D(*CP*AP*AP*TP*GP*CP*AP*AP*TP*G)-3') | | Authors: | Zhu, L, Chou, S.-H, Xu, J, Reid, B.R. | | Deposit date: | 1996-01-24 | | Release date: | 1996-07-11 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure of a single-cytidine hairpin loop formed by the DNA triplet GCA.
Nat.Struct.Biol., 2, 1995
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6B3Y
 | | Crystal structure of the PH-like domain from DENND3 | | Descriptor: | DENN domain-containing protein 3 | | Authors: | Kozlov, G, Xu, J, Menade, M, Beaugrand, M, Pan, T, McPherson, P.S, Gehring, K. | | Deposit date: | 2017-09-25 | | Release date: | 2018-01-24 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.852 Å) | | Cite: | A PH-like domain of the Rab12 guanine nucleotide exchange factor DENND3 binds actin and is required for autophagy.
J. Biol. Chem., 293, 2018
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4KPR
 | | Tetrameric form of rat selenoprotein thioredoxin reductase 1 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, SULFITE ION, ... | | Authors: | Lindqvist, Y, Sandalova, T, Xu, J, Arner, E. | | Deposit date: | 2013-05-14 | | Release date: | 2014-05-14 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The Trp114 residue of thioredoxin reductase 1 is an electron relay sensor for oxidative stress
To be Published, 2013
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6LCP
 | | Cryo-EM structure of Dnf1 from Chaetomium thermophilum in the E2P state | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | He, Y, Xu, J, Wu, X, Li, L. | | Deposit date: | 2019-11-19 | | Release date: | 2020-04-29 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.48 Å) | | Cite: | Structures of a P4-ATPase lipid flippase in lipid bilayers.
Protein Cell, 11, 2020
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6LCR
 | | Cryo-EM structure of Dnf1 from Chaetomium thermophilum in the E1-ATP state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cdc50, ... | | Authors: | He, Y, Xu, J, Wu, X, Li, L. | | Deposit date: | 2019-11-19 | | Release date: | 2020-04-29 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structures of a P4-ATPase lipid flippase in lipid bilayers.
Protein Cell, 11, 2020
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8TNH
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8TNI
 | | Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing bi-specific antibody CAP256L-R27 targeting the CD4-binding site and the V2-apex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 BG505 DS-SOSIP gp120, ... | | Authors: | Zhou, T, Morano, N.C, Roark, R.S, Kwong, P.D, Xu, J. | | Deposit date: | 2023-08-01 | | Release date: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.61 Å) | | Cite: | Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing bi-specific antibody CAP256L-R27 targeting the CD4-binding site and the V2-apex
To Be Published
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8TNG
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2KJ7
 | | Three-Dimensional NMR Structure of Rat Islet Amyloid Polypeptide in DPC micelles | | Descriptor: | Islet amyloid polypeptide | | Authors: | Nanga, R, Brender, J.R, Xu, J, Hartman, K, Subramanian, V, Ramamoorthy, A. | | Deposit date: | 2009-05-22 | | Release date: | 2009-06-23 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | Three-dimensional structure and orientation of rat islet amyloid polypeptide protein in a membrane environment by solution NMR spectroscopy.
J.Am.Chem.Soc., 131, 2009
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6H67
 | | Yeast RNA polymerase I elongation complex stalled by cyclobutane pyrimidine dimer (CPD) | | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | Authors: | Sanz-Murillo, M, Xu, J, Gil-Carton, D, Wang, D, Fernandez-Tornero, C. | | Deposit date: | 2018-07-26 | | Release date: | 2018-08-29 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural basis of RNA polymerase I stalling at UV light-induced DNA damage.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6H68
 | | Yeast RNA polymerase I elongation complex stalled by cyclobutane pyrimidine dimer (CPD) with fully-ordered A49 | | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | Authors: | Sanz-Murillo, M, Xu, J, Gil-Carton, D, Wang, D, Fernandez-Tornero, C. | | Deposit date: | 2018-07-26 | | Release date: | 2018-08-29 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Structural basis of RNA polymerase I stalling at UV light-induced DNA damage.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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9AVA
 | | Co-crystal structure of human TREX1 in complex with an inhibitor | | Descriptor: | (2R)-2-[(5R,6S,8R,9aS)-8-amino-1-oxo-5-(2-phenylethyl)hexahydro-1H-pyrrolo[1,2-a][1,4]diazepin-2(3H)-yl]-N-[(3,4-dichlorophenyl)methyl]-4-methylpentanamide, POTASSIUM ION, Three-prime repair exonuclease 1, ... | | Authors: | Dehghani-Tafti, S, Dong, A, Li, Y, Xu, J, Ackloo, S, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | | Deposit date: | 2024-03-01 | | Release date: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Co-crystal structure of human TREX1 in complex with an inhibitor
To be published
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2KFE
 | | Solution structure of meucin-24 | | Descriptor: | meucin-24 | | Authors: | Du, W, Xu, J, Gao, B, Zhu, S. | | Deposit date: | 2009-02-18 | | Release date: | 2010-01-26 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Characterization of two linear cationic antimalarial peptides in the scorpion Mesobuthus eupeus
Biochimie, 92, 2010
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2M33
 | | Solution NMR structure of full-length oxidized microsomal rabbit cytochrome b5 | | Descriptor: | Cytochrome b5, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Subramanian, V, Ahuja, S, Popovych, N, Huang, R, Le Clair, S.V, Jahr, N, Soong, R, Xu, J, Yamamoto, K, Nanga, R.P, Im, S, Waskell, L, Ramamoorthy, A. | | Deposit date: | 2013-01-08 | | Release date: | 2013-02-06 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | NMR structure of full-length mammalian cytochrome b5
To be Published
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3QXL
 | | Crystal structure of the CDC25 Domain from Ral-specific Guanine-nucleotide Exchange Factor RalGPS1a | | Descriptor: | Ras-specific guanine nucleotide-releasing factor RalGPS1 | | Authors: | Peng, W, Xu, J, Guan, X, Sun, Y, Li, X, Zhang, X.C, Rao, Z. | | Deposit date: | 2011-03-02 | | Release date: | 2011-05-11 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.237 Å) | | Cite: | Structural study of the Cdc25 domain from Ral-specific guanine-nucleotide exchange factor RalGPS1a.
Protein Cell, 2, 2011
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8HCU
 | | Crystal structure of BCOR/PCGF1/KDM2B complex | | Descriptor: | ACETIC ACID, BCL-6 corepressor, Polycomb group RING finger protein 1, ... | | Authors: | Shen, F, Chen, R, Xu, J, Liu, J. | | Deposit date: | 2022-11-03 | | Release date: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of BCOR/PCGF1/KDM2B complex
to be published
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8HQL
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8JT3
 | | Crystal structure of aminotransferase CrmG from Actinoalloteichus sp. WH1-2216-6 in complex with amino donor L-Arg | | Descriptor: | (E)-N~2~-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-arginine, ACETATE ION, CrmG, ... | | Authors: | Su, K, Zhang, Y, Xu, J, Liu, J. | | Deposit date: | 2023-06-21 | | Release date: | 2023-08-02 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Co-crystal structure provides insights on transaminase CrmG recognition amino donor L-Arg.
Biochem.Biophys.Res.Commun., 675, 2023
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7WF9
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7WF8
 | | Crystal structure of mouse SNX25 RGS domain in space group P212121 | | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Zhang, Y, Xu, J, Liu, J. | | Deposit date: | 2021-12-26 | | Release date: | 2022-10-26 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Structural Studies Reveal Unique Non-canonical Regulators of G Protein Signaling Homology (RH) Domains in Sorting Nexins.
J.Mol.Biol., 434, 2022
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7UDB
 | | Cryo-EM structure of a synaptobrevin-Munc18-1-syntaxin-1 complex class 2 | | Descriptor: | Synaptobrevin-2, Syntaxin-1A, Syntaxin-binding protein 1 | | Authors: | Rizo, J, Bai, X, Stepien, K.P, Xu, J, Zhang, X. | | Deposit date: | 2022-03-18 | | Release date: | 2022-04-06 | | Last modified: | 2022-07-06 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | SNARE assembly enlightened by cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex.
Sci Adv, 8, 2022
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7UDC
 | | cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex class1 | | Descriptor: | Synaptobrevin-2, Syntaxin-1A, Syntaxin-binding protein 1 | | Authors: | Rizo, J, Bai, X, Stepien, K.P, Xu, J, Zhang, X. | | Deposit date: | 2022-03-18 | | Release date: | 2022-04-06 | | Last modified: | 2022-07-06 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | SNARE assembly enlightened by cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex.
Sci Adv, 8, 2022
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