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PDB: 80 件
3MHS
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BU of 3mhs by Molmil
Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module bound to ubiquitin aldehyde
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Protein SUS1, ...
著者Samara, N.L, Datta, A.B, Berndsen, C.E, Zhang, X, Yao, T, Cohen, R.E, Wolberger, C.
登録日2010-04-08
公開日2010-04-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structural insights into the assembly and function of the SAGA deubiquitinating module.
Science, 328, 2010
3MHH
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BU of 3mhh by Molmil
Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module
分子名称: Protein SUS1, SAGA-associated factor 11, SAGA-associated factor 73, ...
著者Samara, N.L, Datta, A.B, Berndsen, C.E, Zhang, X, Yao, T, Cohen, R.E, Wolberger, C.
登録日2010-04-08
公開日2010-04-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural insights into the assembly and function of the SAGA deubiquitinating module.
Science, 328, 2010
1YC2
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BU of 1yc2 by Molmil
Sir2Af2-NAD-ADPribose-nicotinamide
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5-DIPHOSPHORIBOSE, NAD-dependent deacetylase 2, ...
著者Avalos, J.L, Bever, M.K, Wolberger, C.
登録日2004-12-21
公開日2005-03-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mechanism of Sirtuin Inhibition by Nicotinamide: Altering the NAD(+) Cosubstrate Specificity of a Sir2 Enzyme.
Mol.Cell, 17, 2005
1YC5
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BU of 1yc5 by Molmil
Sir2-p53 peptide-nicotinamide
分子名称: Cellular tumor antigen p53 peptide, NAD-dependent deacetylase, NICOTINAMIDE, ...
著者Avalos, J.L, Bever, M.K, Wolberger, C.
登録日2004-12-21
公開日2005-04-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme.
Mol.Cell, 17, 2005
2AAC
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BU of 2aac by Molmil
ESCHERCHIA COLI GENE REGULATORY PROTEIN ARAC COMPLEXED WITH D-FUCOSE
分子名称: ACETIC ACID, ARAC, beta-D-fucopyranose
著者Soisson, S.M, Wolberger, C.
登録日1996-10-31
公開日1997-11-12
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The 1.6 A crystal structure of the AraC sugar-binding and dimerization domain complexed with D-fucose.
J.Mol.Biol., 273, 1997
1JAT
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BU of 1jat by Molmil
Mms2/Ubc13 Ubiquitin Conjugating Enzyme Complex
分子名称: Ubiquitin-Conjugating Enzyme E2-17.5 KDA, Ubiquitin-Conjugating Enzyme Variant Mms2
著者VanDemark, A.P, Hofmann, R.M, Tsui, C, Pickart, C.M, Wolberger, C.
登録日2001-05-31
公開日2001-06-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer.
Cell(Cambridge,Mass.), 105, 2001
1JBB
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BU of 1jbb by Molmil
Ubiquitin Conjugating Enzyme, Ubc13
分子名称: ubiquitin conjugating enzyme E2-17.5 KDA
著者VanDemark, A.P, Hofmann, R.M, Tsui, C, Pickart, C.M, Wolberger, C.
登録日2001-06-03
公開日2001-06-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer.
Cell(Cambridge,Mass.), 105, 2001
4DHI
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BU of 4dhi by Molmil
Structure of C. elegans OTUB1 bound to human UBC13
分子名称: Ubiquitin thioesterase otubain-like, Ubiquitin-conjugating enzyme E2 N
著者Wiener, R, Zhang, X, Wang, T, Wolberger, C.
登録日2012-01-27
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The mechanism of OTUB1-mediated inhibition of ubiquitination.
Nature, 483, 2012
4DHJ
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The structure of a ceOTUB1 ubiquitin aldehyde UBC13~Ub complex
分子名称: Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ...
著者Wiener, R, Zhang, X, Wang, T, Wolberger, C.
登録日2012-01-27
公開日2012-02-22
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The mechanism of OTUB1-mediated inhibition of ubiquitination.
Nature, 483, 2012
4DHZ
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BU of 4dhz by Molmil
The structure of h/ceOTUB1-ubiquitin aldehyde-UBC13~Ub
分子名称: Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ...
著者Wiener, R, Zhang, X, Wang, T, Wolberger, C.
登録日2012-01-30
公開日2012-02-22
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献The mechanism of OTUB1-mediated inhibition of ubiquitination.
Nature, 483, 2012
4FH1
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BU of 4fh1 by Molmil
S. cerevisiae Ubc13-N79A
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Ubiquitin-conjugating enzyme E2 13
著者Berndsen, C.E, Wolberger, C, Wiener, R.
登録日2012-06-05
公開日2013-01-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献A conserved asparagine has a structural role in ubiquitin-conjugating enzymes.
Nat.Chem.Biol., 9, 2013
4FIP
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BU of 4fip by Molmil
Structure of the SAGA Ubp8(S144N)/Sgf11(1-72, Delta-ZnF)/Sus1/Sgf73 DUB module
分子名称: Protein SUS1, SAGA-associated factor 11, SAGA-associated factor 73, ...
著者Samara, N.L, Ringel, A.E, Wolberger, C.
登録日2012-06-10
公開日2012-07-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.686 Å)
主引用文献A Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and Activity.
Structure, 20, 2012
1K78
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BU of 1k78 by Molmil
Pax5(1-149)+Ets-1(331-440)+DNA
分子名称: C-ets-1 Protein, Paired Box Protein Pax5, Pax5/Ets Binding Site on the mb-1 promoter
著者Garvie, C.W, Hagman, J, Wolberger, C.
登録日2001-10-18
公開日2002-01-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural studies of Ets-1/Pax5 complex formation on DNA.
Mol.Cell, 8, 2001
1K79
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BU of 1k79 by Molmil
Ets-1(331-440)+GGAA duplex
分子名称: C-ets-1 protein, DNA (5'-D(*CP*AP*CP*AP*TP*TP*TP*CP*CP*GP*GP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*CP*CP*GP*GP*AP*AP*AP*TP*GP*T)-3')
著者Garvie, C.W, Hagman, J, Wolberger, C.
登録日2001-10-18
公開日2002-01-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural studies of Ets-1/Pax5 complex formation on DNA.
Mol.Cell, 8, 2001
1K7A
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BU of 1k7a by Molmil
Ets-1(331-440)+GGAG duplex
分子名称: C-ets-1 Protein, DNA (5'-D(*CP*AP*CP*AP*TP*CP*TP*CP*CP*GP*GP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*CP*CP*GP*GP*AP*GP*AP*TP*GP*T)-3')
著者Garvie, C.W, Hagman, J, Wolberger, C.
登録日2001-10-18
公開日2002-01-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural studies of Ets-1/Pax5 complex formation on DNA.
Mol.Cell, 8, 2001
1K61
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BU of 1k61 by Molmil
MATALPHA2 HOMEODOMAIN BOUND TO DNA
分子名称: 5'-D(*(5IU)P*GP*CP*GP*TP*GP*TP*AP*AP*AP*TP*GP*AP*AP*TP*TP*AP*CP*AP*TP*G)-3', 5'-D(*AP*CP*AP*TP*GP*TP*AP*AP*TP*TP*CP*AP*TP*TP*TP*AP*CP*AP*CP*GP*C)-3', Mating-type protein alpha-2
著者Aishima, J, Gitti, R.K, Noah, J.E, Gan, H.H, Schlick, T, Wolberger, C.
登録日2001-10-14
公開日2002-12-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A Hoogsteen base pair embedded in undistorted B-DNA
NUCLEIC ACIDS RES., 30, 2002
1LE8
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BU of 1le8 by Molmil
Crystal Structure of the MATa1/MATalpha2-3A Heterodimer Bound to DNA Complex
分子名称: 5'-D(*AP*CP*AP*TP*GP*TP*AP*AP*AP*AP*AP*TP*TP*TP*AP*CP*AP*TP*CP*A)-3', 5'-D(*TP*TP*GP*AP*TP*GP*TP*AP*AP*AP*TP*TP*TP*TP*TP*AP*CP*AP*TP*G)-3', MATING-TYPE PROTEIN A-1, ...
著者Ke, A, Mathias, J.R, Vershon, A.K, Wolberger, C.
登録日2002-04-09
公開日2002-05-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Thermodynamic Characterization of the DNA Binding Properties of a Triple Alanine Mutant of MATalpha2
Structure, 10, 2002
2JE0
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BU of 2je0 by Molmil
Crystal Structure of pp32
分子名称: ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A, GLYCEROL
著者Huyton, T, Wolberger, C.
登録日2007-01-12
公開日2007-06-26
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Crystal Structure of the Tumor Suppressor Protein Pp32 (Anp32A): Structural Insights Into Anp32 Family of Proteins.
Protein Sci., 16, 2007
2H4H
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BU of 2h4h by Molmil
Sir2 H116Y mutant-p53 peptide-NAD
分子名称: Cellular tumor antigen p53, NAD-dependent deacetylase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Hoff, K.G, Avalos, J.L, Sens, K, Wolberger, C.
登録日2006-05-24
公開日2006-09-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide.
Structure, 14, 2006
2H4J
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BU of 2h4j by Molmil
Sir2-deacetylated peptide (from enzymatic turnover in crystal)
分子名称: 2'-O-ACETYL ADENOSINE-5-DIPHOSPHORIBOSE, Cellular tumor antigen p53, NAD-dependent deacetylase, ...
著者Hoff, K.G, Avalos, J.L, Sens, K, Wolberger, C.
登録日2006-05-24
公開日2006-09-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide.
Structure, 14, 2006
2H2I
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BU of 2h2i by Molmil
The Structural basis of Sirtuin Substrate Affinity
分子名称: (2S,5R,8R,11S,14S,17S,21R)-5,8,11,14,17-PENTAMETHYL-4,7,10,13,16,19-HEXAOXADOCOSANE-2,21-DIOL, NAD-dependent deacetylase, ZINC ION
著者Cosgrove, M.S, Wolberger, C.
登録日2006-05-18
公開日2006-12-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structural basis of sirtuin substrate affinity
Biochemistry, 45, 2006
2H2G
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BU of 2h2g by Molmil
The Structural Basis of Sirtuin substrate affinity
分子名称: HISTONE H3 PEPTIDE, NAD-dependent deacetylase, ZINC ION
著者Cosgrove, M.S, Wolberger, C.
登録日2006-05-18
公開日2006-11-28
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献The structural basis of sirtuin substrate affinity
Biochemistry, 45, 2006
2H2D
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BU of 2h2d by Molmil
The Structural Basis for Sirtuin Substrate Affinity
分子名称: Cellular tumor antigen p53 peptide, NAD-dependent deacetylase, ZINC ION
著者Cosgrove, M.S, Wolberger, C.
登録日2006-05-18
公開日2006-09-19
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献On the Structural Basis of Sirtuin Substrate Affinity
Biochemistry, 45, 2006
2H2F
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The Structural basis for Sirtuin Substrate affinity
分子名称: Cellular tumor antigen p53, NAD-dependent deacetylase, ZINC ION
著者Cosgrove, M.S, Wolberger, C.
登録日2006-05-18
公開日2006-12-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structural basis of sirtuin substrate affinity
Biochemistry, 45, 2006
2H3D
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Crystal Structure of Mouse Nicotinamide Phosphoribosyltransferase/Visfatin/Pre-B Cell Colony Enhancing Factor in Complex with Nicotinamide Mononuleotide
分子名称: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, Nicotinamide phosphoribosyltransferase
著者Wang, T, Zhang, X, Bheda, P, Revollo, J.R, Imai, S.I, Wolberger, C.
登録日2006-05-22
公開日2006-06-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of Nampt/PBEF/visfatin, a mammalian NAD(+) biosynthetic enzyme.
Nat.Struct.Mol.Biol., 13, 2006

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