3D81
| Sir2-S-alkylamidate complex crystal structure | 分子名称: | NAD-dependent deacetylase, S-alkylamidate intermediate, ZINC ION | 著者 | Hawse, W.F, Hoff, K.G, Fatkins, D, Daines, A, Zubkova, O.V, Schramm, V.L, Zheng, W, Wolberger, C. | 登録日 | 2008-05-22 | 公開日 | 2008-09-30 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural insights into intermediate steps in the Sir2 deacetylation reaction. Structure, 16, 2008
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4FH1
| S. cerevisiae Ubc13-N79A | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Ubiquitin-conjugating enzyme E2 13 | 著者 | Berndsen, C.E, Wolberger, C, Wiener, R. | 登録日 | 2012-06-05 | 公開日 | 2013-01-09 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | A conserved asparagine has a structural role in ubiquitin-conjugating enzymes. Nat.Chem.Biol., 9, 2013
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4FIP
| Structure of the SAGA Ubp8(S144N)/Sgf11(1-72, Delta-ZnF)/Sus1/Sgf73 DUB module | 分子名称: | Protein SUS1, SAGA-associated factor 11, SAGA-associated factor 73, ... | 著者 | Samara, N.L, Ringel, A.E, Wolberger, C. | 登録日 | 2012-06-10 | 公開日 | 2012-07-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.686 Å) | 主引用文献 | A Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and Activity. Structure, 20, 2012
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4FK5
| Structure of the SAGA Ubp8(S144N)/Sgf11/Sus1/Sgf73 DUB module | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Protein SUS1, ... | 著者 | Samara, N.L, Ringel, A.E, Wolberger, C. | 登録日 | 2012-06-12 | 公開日 | 2012-07-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.032 Å) | 主引用文献 | A Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and Activity. Structure, 20, 2012
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4FJC
| Structure of the SAGA Ubp8/Sgf11(1-72, Delta-ZnF)/Sus1/Sgf73 DUB module | 分子名称: | GLYCEROL, Protein SUS1, SAGA-associated factor 11, ... | 著者 | Samara, N.L, Ringel, A.E, Wolberger, C. | 登録日 | 2012-06-11 | 公開日 | 2012-07-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.826 Å) | 主引用文献 | A Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and Activity. Structure, 20, 2012
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2ARC
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2CRO
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2AAC
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2ARA
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1JAT
| Mms2/Ubc13 Ubiquitin Conjugating Enzyme Complex | 分子名称: | Ubiquitin-Conjugating Enzyme E2-17.5 KDA, Ubiquitin-Conjugating Enzyme Variant Mms2 | 著者 | VanDemark, A.P, Hofmann, R.M, Tsui, C, Pickart, C.M, Wolberger, C. | 登録日 | 2001-05-31 | 公開日 | 2001-06-20 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer. Cell(Cambridge,Mass.), 105, 2001
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1JBB
| Ubiquitin Conjugating Enzyme, Ubc13 | 分子名称: | ubiquitin conjugating enzyme E2-17.5 KDA | 著者 | VanDemark, A.P, Hofmann, R.M, Tsui, C, Pickart, C.M, Wolberger, C. | 登録日 | 2001-06-03 | 公開日 | 2001-06-20 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer. Cell(Cambridge,Mass.), 105, 2001
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1K61
| MATALPHA2 HOMEODOMAIN BOUND TO DNA | 分子名称: | 5'-D(*(5IU)P*GP*CP*GP*TP*GP*TP*AP*AP*AP*TP*GP*AP*AP*TP*TP*AP*CP*AP*TP*G)-3', 5'-D(*AP*CP*AP*TP*GP*TP*AP*AP*TP*TP*CP*AP*TP*TP*TP*AP*CP*AP*CP*GP*C)-3', Mating-type protein alpha-2 | 著者 | Aishima, J, Gitti, R.K, Noah, J.E, Gan, H.H, Schlick, T, Wolberger, C. | 登録日 | 2001-10-14 | 公開日 | 2002-12-11 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A Hoogsteen base pair embedded in undistorted B-DNA NUCLEIC ACIDS RES., 30, 2002
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1K78
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1K79
| Ets-1(331-440)+GGAA duplex | 分子名称: | C-ets-1 protein, DNA (5'-D(*CP*AP*CP*AP*TP*TP*TP*CP*CP*GP*GP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*CP*CP*GP*GP*AP*AP*AP*TP*GP*T)-3') | 著者 | Garvie, C.W, Hagman, J, Wolberger, C. | 登録日 | 2001-10-18 | 公開日 | 2002-01-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural studies of Ets-1/Pax5 complex formation on DNA. Mol.Cell, 8, 2001
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1K7A
| Ets-1(331-440)+GGAG duplex | 分子名称: | C-ets-1 Protein, DNA (5'-D(*CP*AP*CP*AP*TP*CP*TP*CP*CP*GP*GP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*CP*CP*GP*GP*AP*GP*AP*TP*GP*T)-3') | 著者 | Garvie, C.W, Hagman, J, Wolberger, C. | 登録日 | 2001-10-18 | 公開日 | 2002-01-04 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural studies of Ets-1/Pax5 complex formation on DNA. Mol.Cell, 8, 2001
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1LE8
| Crystal Structure of the MATa1/MATalpha2-3A Heterodimer Bound to DNA Complex | 分子名称: | 5'-D(*AP*CP*AP*TP*GP*TP*AP*AP*AP*AP*AP*TP*TP*TP*AP*CP*AP*TP*CP*A)-3', 5'-D(*TP*TP*GP*AP*TP*GP*TP*AP*AP*AP*TP*TP*TP*TP*TP*AP*CP*AP*TP*G)-3', MATING-TYPE PROTEIN A-1, ... | 著者 | Ke, A, Mathias, J.R, Vershon, A.K, Wolberger, C. | 登録日 | 2002-04-09 | 公開日 | 2002-05-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and Thermodynamic Characterization of the DNA Binding Properties of a Triple Alanine Mutant of MATalpha2 Structure, 10, 2002
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1MH3
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1MH4
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1MDM
| INHIBITED FRAGMENT OF ETS-1 AND PAIRED DOMAIN OF PAX5 BOUND TO DNA | 分子名称: | C-ETS-1 PROTEIN, PAIRED BOX PROTEIN PAX-5, PAX5/ETS BINDING SITE ON THE MB-1 PROMOTER | 著者 | Garvie, C.W, Pufall, M.A, Graves, B.J, Wolberger, C. | 登録日 | 2002-08-07 | 公開日 | 2002-12-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | STRUCTURAL ANALYSIS OF THE AUTOINHIBITION OF ETS-1 AND ITS ROLE IN PROTEIN PARTNERSHIPS J.Biol.Chem., 277, 2002
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1MD0
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1MA3
| Structure of a Sir2 enzyme bound to an acetylated p53 peptide | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cellular tumor antigen p53, Transcriptional regulatory protein, ... | 著者 | Avalos, J.L, Celic, I, Muhammad, S, Cosgrove, M.S, Boeke, J.D, Wolberger, C. | 登録日 | 2002-07-31 | 公開日 | 2002-10-16 | 最終更新日 | 2024-11-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of a Sir2 enzyme bound to an acetylated p53 peptide Mol.Cell, 10, 2002
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2H4J
| Sir2-deacetylated peptide (from enzymatic turnover in crystal) | 分子名称: | 2'-O-ACETYL ADENOSINE-5-DIPHOSPHORIBOSE, Cellular tumor antigen p53, NAD-dependent deacetylase, ... | 著者 | Hoff, K.G, Avalos, J.L, Sens, K, Wolberger, C. | 登録日 | 2006-05-24 | 公開日 | 2006-09-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide. Structure, 14, 2006
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2H2D
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2H2F
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2H59
| Sir2 H116A-deacetylated p53 peptide-3'-o-acetyl ADP ribose | 分子名称: | (2S,3S,4R,5S)-2-({[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]OXY}METHYL)-4,5-DIHYDROXYTETRAHYDROFURAN-3-YL ACETATE, ADENOSINE-5-DIPHOSPHORIBOSE, Cellular tumor antigen p53, ... | 著者 | Hoff, K.G, Avalos, J.L, Sens, K, Wolberger, C. | 登録日 | 2006-05-25 | 公開日 | 2006-09-05 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide. Structure, 14, 2006
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