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PDB: 84 件

3D81
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Sir2-S-alkylamidate complex crystal structure
分子名称: NAD-dependent deacetylase, S-alkylamidate intermediate, ZINC ION
著者Hawse, W.F, Hoff, K.G, Fatkins, D, Daines, A, Zubkova, O.V, Schramm, V.L, Zheng, W, Wolberger, C.
登録日2008-05-22
公開日2008-09-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into intermediate steps in the Sir2 deacetylation reaction.
Structure, 16, 2008
4FH1
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S. cerevisiae Ubc13-N79A
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Ubiquitin-conjugating enzyme E2 13
著者Berndsen, C.E, Wolberger, C, Wiener, R.
登録日2012-06-05
公開日2013-01-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献A conserved asparagine has a structural role in ubiquitin-conjugating enzymes.
Nat.Chem.Biol., 9, 2013
4FIP
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BU of 4fip by Molmil
Structure of the SAGA Ubp8(S144N)/Sgf11(1-72, Delta-ZnF)/Sus1/Sgf73 DUB module
分子名称: Protein SUS1, SAGA-associated factor 11, SAGA-associated factor 73, ...
著者Samara, N.L, Ringel, A.E, Wolberger, C.
登録日2012-06-10
公開日2012-07-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.686 Å)
主引用文献A Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and Activity.
Structure, 20, 2012
4FK5
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Structure of the SAGA Ubp8(S144N)/Sgf11/Sus1/Sgf73 DUB module
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Protein SUS1, ...
著者Samara, N.L, Ringel, A.E, Wolberger, C.
登録日2012-06-12
公開日2012-07-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.032 Å)
主引用文献A Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and Activity.
Structure, 20, 2012
4FJC
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Structure of the SAGA Ubp8/Sgf11(1-72, Delta-ZnF)/Sus1/Sgf73 DUB module
分子名称: GLYCEROL, Protein SUS1, SAGA-associated factor 11, ...
著者Samara, N.L, Ringel, A.E, Wolberger, C.
登録日2012-06-11
公開日2012-07-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.826 Å)
主引用文献A Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and Activity.
Structure, 20, 2012
2ARC
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BU of 2arc by Molmil
ESCHERICHIA COLI REGULATORY PROTEIN ARAC COMPLEXED WITH L-ARABINOSE
分子名称: ARABINOSE OPERON REGULATORY PROTEIN, alpha-L-arabinopyranose
著者Soisson, S.M, Wolberger, C.
登録日1996-10-29
公開日1997-05-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis for ligand-regulated oligomerization of AraC.
Science, 276, 1997
2CRO
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BU of 2cro by Molmil
STRUCTURE OF PHAGE 434 CRO PROTEIN AT 2.35 ANGSTROMS RESOLUTION
分子名称: REGULATORY PROTEIN CRO
著者Mondragon, A, Wolberger, C, Harrison, S.C.
登録日1988-12-08
公開日1989-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure of phage 434 Cro protein at 2.35 A resolution.
J.Mol.Biol., 205, 1989
2AAC
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ESCHERCHIA COLI GENE REGULATORY PROTEIN ARAC COMPLEXED WITH D-FUCOSE
分子名称: ACETIC ACID, ARAC, beta-D-fucopyranose
著者Soisson, S.M, Wolberger, C.
登録日1996-10-31
公開日1997-11-12
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The 1.6 A crystal structure of the AraC sugar-binding and dimerization domain complexed with D-fucose.
J.Mol.Biol., 273, 1997
2ARA
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APO FORM OF ESCHERICHIA COLI REGULATORY PROTEIN ARAC
分子名称: ARAC
著者Soisson, S.M, Wolberger, C.
登録日1996-10-30
公開日1997-05-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for ligand-regulated oligomerization of AraC.
Science, 276, 1997
1JAT
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Mms2/Ubc13 Ubiquitin Conjugating Enzyme Complex
分子名称: Ubiquitin-Conjugating Enzyme E2-17.5 KDA, Ubiquitin-Conjugating Enzyme Variant Mms2
著者VanDemark, A.P, Hofmann, R.M, Tsui, C, Pickart, C.M, Wolberger, C.
登録日2001-05-31
公開日2001-06-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer.
Cell(Cambridge,Mass.), 105, 2001
1JBB
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Ubiquitin Conjugating Enzyme, Ubc13
分子名称: ubiquitin conjugating enzyme E2-17.5 KDA
著者VanDemark, A.P, Hofmann, R.M, Tsui, C, Pickart, C.M, Wolberger, C.
登録日2001-06-03
公開日2001-06-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer.
Cell(Cambridge,Mass.), 105, 2001
1K61
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MATALPHA2 HOMEODOMAIN BOUND TO DNA
分子名称: 5'-D(*(5IU)P*GP*CP*GP*TP*GP*TP*AP*AP*AP*TP*GP*AP*AP*TP*TP*AP*CP*AP*TP*G)-3', 5'-D(*AP*CP*AP*TP*GP*TP*AP*AP*TP*TP*CP*AP*TP*TP*TP*AP*CP*AP*CP*GP*C)-3', Mating-type protein alpha-2
著者Aishima, J, Gitti, R.K, Noah, J.E, Gan, H.H, Schlick, T, Wolberger, C.
登録日2001-10-14
公開日2002-12-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A Hoogsteen base pair embedded in undistorted B-DNA
NUCLEIC ACIDS RES., 30, 2002
1K78
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Pax5(1-149)+Ets-1(331-440)+DNA
分子名称: C-ets-1 Protein, Paired Box Protein Pax5, Pax5/Ets Binding Site on the mb-1 promoter
著者Garvie, C.W, Hagman, J, Wolberger, C.
登録日2001-10-18
公開日2002-01-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural studies of Ets-1/Pax5 complex formation on DNA.
Mol.Cell, 8, 2001
1K79
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Ets-1(331-440)+GGAA duplex
分子名称: C-ets-1 protein, DNA (5'-D(*CP*AP*CP*AP*TP*TP*TP*CP*CP*GP*GP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*CP*CP*GP*GP*AP*AP*AP*TP*GP*T)-3')
著者Garvie, C.W, Hagman, J, Wolberger, C.
登録日2001-10-18
公開日2002-01-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural studies of Ets-1/Pax5 complex formation on DNA.
Mol.Cell, 8, 2001
1K7A
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Ets-1(331-440)+GGAG duplex
分子名称: C-ets-1 Protein, DNA (5'-D(*CP*AP*CP*AP*TP*CP*TP*CP*CP*GP*GP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*CP*CP*GP*GP*AP*GP*AP*TP*GP*T)-3')
著者Garvie, C.W, Hagman, J, Wolberger, C.
登録日2001-10-18
公開日2002-01-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural studies of Ets-1/Pax5 complex formation on DNA.
Mol.Cell, 8, 2001
1LE8
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BU of 1le8 by Molmil
Crystal Structure of the MATa1/MATalpha2-3A Heterodimer Bound to DNA Complex
分子名称: 5'-D(*AP*CP*AP*TP*GP*TP*AP*AP*AP*AP*AP*TP*TP*TP*AP*CP*AP*TP*CP*A)-3', 5'-D(*TP*TP*GP*AP*TP*GP*TP*AP*AP*AP*TP*TP*TP*TP*TP*AP*CP*AP*TP*G)-3', MATING-TYPE PROTEIN A-1, ...
著者Ke, A, Mathias, J.R, Vershon, A.K, Wolberger, C.
登録日2002-04-09
公開日2002-05-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Thermodynamic Characterization of the DNA Binding Properties of a Triple Alanine Mutant of MATalpha2
Structure, 10, 2002
1MH3
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maltose binding-a1 homeodomain protein chimera, crystal form I
分子名称: maltose binding-a1 homeodomain protein chimera
著者Ke, A, Wolberger, C.
登録日2002-08-19
公開日2002-09-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Insights into binding cooperativity of MATa1/MATalpha2 from the crystal structure of a MATa1 homeodomain-maltose binding protein chimera
Protein Sci., 12, 2003
1MH4
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maltose binding-a1 homeodomain protein chimera, crystal form II
分子名称: maltose binding-a1 homeodomain protein chimera
著者Ke, A, Wolberger, C.
登録日2002-08-19
公開日2002-09-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Insights into binding cooperativity of MATa1/MATalpha2 from the crystal structure of a MATa1 homeodomain-maltose binding protein chimera
Protein Sci., 12, 2003
1MDM
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BU of 1mdm by Molmil
INHIBITED FRAGMENT OF ETS-1 AND PAIRED DOMAIN OF PAX5 BOUND TO DNA
分子名称: C-ETS-1 PROTEIN, PAIRED BOX PROTEIN PAX-5, PAX5/ETS BINDING SITE ON THE MB-1 PROMOTER
著者Garvie, C.W, Pufall, M.A, Graves, B.J, Wolberger, C.
登録日2002-08-07
公開日2002-12-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献STRUCTURAL ANALYSIS OF THE AUTOINHIBITION OF ETS-1 AND ITS ROLE IN PROTEIN PARTNERSHIPS
J.Biol.Chem., 277, 2002
1MD0
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CRYSTAL STRUCTURE OF AN INHIBITED FRAGMENT OF Ets-1
分子名称: C-ets-1 protein
著者Garvie, C.W, Pufall, M.A, Graves, B.J, Wolberger, C.
登録日2002-08-06
公開日2002-12-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Analysis of the Autoinhibition of Ets-1 and Its Role in Protein Partnerships
J.Biol.Chem., 277, 2002
1MA3
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Structure of a Sir2 enzyme bound to an acetylated p53 peptide
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cellular tumor antigen p53, Transcriptional regulatory protein, ...
著者Avalos, J.L, Celic, I, Muhammad, S, Cosgrove, M.S, Boeke, J.D, Wolberger, C.
登録日2002-07-31
公開日2002-10-16
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of a Sir2 enzyme bound to an acetylated p53 peptide
Mol.Cell, 10, 2002
2H4J
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Sir2-deacetylated peptide (from enzymatic turnover in crystal)
分子名称: 2'-O-ACETYL ADENOSINE-5-DIPHOSPHORIBOSE, Cellular tumor antigen p53, NAD-dependent deacetylase, ...
著者Hoff, K.G, Avalos, J.L, Sens, K, Wolberger, C.
登録日2006-05-24
公開日2006-09-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide.
Structure, 14, 2006
2H2D
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The Structural Basis for Sirtuin Substrate Affinity
分子名称: Cellular tumor antigen p53 peptide, NAD-dependent deacetylase, ZINC ION
著者Cosgrove, M.S, Wolberger, C.
登録日2006-05-18
公開日2006-09-19
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献On the Structural Basis of Sirtuin Substrate Affinity
Biochemistry, 45, 2006
2H2F
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The Structural basis for Sirtuin Substrate affinity
分子名称: Cellular tumor antigen p53, NAD-dependent deacetylase, ZINC ION
著者Cosgrove, M.S, Wolberger, C.
登録日2006-05-18
公開日2006-12-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structural basis of sirtuin substrate affinity
Biochemistry, 45, 2006
2H59
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Sir2 H116A-deacetylated p53 peptide-3'-o-acetyl ADP ribose
分子名称: (2S,3S,4R,5S)-2-({[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]OXY}METHYL)-4,5-DIHYDROXYTETRAHYDROFURAN-3-YL ACETATE, ADENOSINE-5-DIPHOSPHORIBOSE, Cellular tumor antigen p53, ...
著者Hoff, K.G, Avalos, J.L, Sens, K, Wolberger, C.
登録日2006-05-25
公開日2006-09-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide.
Structure, 14, 2006

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