2H2I
The Structural basis of Sirtuin Substrate Affinity
Summary for 2H2I
Entry DOI | 10.2210/pdb2h2i/pdb |
Descriptor | NAD-dependent deacetylase, ZINC ION, (2S,5R,8R,11S,14S,17S,21R)-5,8,11,14,17-PENTAMETHYL-4,7,10,13,16,19-HEXAOXADOCOSANE-2,21-DIOL, ... (4 entities in total) |
Functional Keywords | sir2tm-ppg, hydrolase |
Biological source | Thermotoga maritima |
Cellular location | Cytoplasm (By similarity): Q9WYW0 |
Total number of polymer chains | 1 |
Total formula weight | 28059.77 |
Authors | Cosgrove, M.S.,Wolberger, C. (deposition date: 2006-05-18, release date: 2006-12-05, Last modification date: 2023-08-30) |
Primary citation | Cosgrove, M.S.,Bever, K.,Avalos, J.L.,Muhammad, S.,Zhang, X.,Wolberger, C. The structural basis of sirtuin substrate affinity Biochemistry, 45:7511-7521, 2006 Cited by PubMed: 16768447DOI: 10.1021/bi0526332 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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