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2H4F

Sir2-p53 peptide-NAD+

Summary for 2H4F
Entry DOI10.2210/pdb2h4f/pdb
DescriptorNAD-dependent deacetylase, Cellular tumor antigen p53, ZINC ION, ... (5 entities in total)
Functional Keywordssir2 ternary complex, hydrolase
Biological sourceThermotoga maritima
More
Cellular locationCytoplasm (Probable): Q9WYW0
Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: Q9NP68
Total number of polymer chains2
Total formula weight30438.15
Authors
Hoff, K.G.,Avalos, J.L.,Sens, K.,Wolberger, C. (deposition date: 2006-05-24, release date: 2006-09-05, Last modification date: 2023-11-15)
Primary citationHoff, K.G.,Avalos, J.L.,Sens, K.,Wolberger, C.
Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide.
Structure, 14:1231-1240, 2006
Cited by
PubMed: 16905097
DOI: 10.1016/j.str.2006.06.006
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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