2H2G
The Structural Basis of Sirtuin substrate affinity
Summary for 2H2G
Entry DOI | 10.2210/pdb2h2g/pdb |
Descriptor | NAD-dependent deacetylase, HISTONE H3 PEPTIDE, ZINC ION, ... (4 entities in total) |
Functional Keywords | h3-k115ac, sir2, sir2tm, sirtuin, sirt1, histone h3, hydrolase |
Biological source | Thermotoga maritima More |
Total number of polymer chains | 2 |
Total formula weight | 29070.22 |
Authors | Cosgrove, M.S.,Wolberger, C. (deposition date: 2006-05-18, release date: 2006-11-28, Last modification date: 2019-07-24) |
Primary citation | Cosgrove, M.S.,Bever, K.,Avalos, J.L.,Muhammad, S.,Zhang, X.,Wolberger, C. The structural basis of sirtuin substrate affinity Biochemistry, 45:7511-7521, 2006 Cited by PubMed: 16768447DOI: 10.1021/bi0526332 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.63 Å) |
Structure validation
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