2H59
Sir2 H116A-deacetylated p53 peptide-3'-o-acetyl ADP ribose
Summary for 2H59
Entry DOI | 10.2210/pdb2h59/pdb |
Related | 2H4F 2H4H 2H4J |
Descriptor | NAD-dependent deacetylase, Cellular tumor antigen p53, ZINC ION, ... (6 entities in total) |
Functional Keywords | rossmann fold, zn binding domain, hydrolase |
Biological source | Thermotoga maritima More |
Cellular location | Cytoplasm : Q9WYW0 |
Total number of polymer chains | 4 |
Total formula weight | 60493.92 |
Authors | Hoff, K.G.,Avalos, J.L.,Sens, K.,Wolberger, C. (deposition date: 2006-05-25, release date: 2006-09-05, Last modification date: 2023-08-30) |
Primary citation | Hoff, K.G.,Avalos, J.L.,Sens, K.,Wolberger, C. Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide. Structure, 14:1231-1240, 2006 Cited by PubMed: 16905097DOI: 10.1016/j.str.2006.06.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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