2H2H

The Structural basis of sirtuin substrate specificity

Summary for 2H2H

• Entry DOI: 10.2210/pdb2h2h/pdb
• Descriptor: NAD-dependent deacetylase, Histone H4, ZINC ION, ... (4 entities in total)
• Functional Keywords: h4-k79ac, hydrolase
• Biological source: Thermotoga maritima
• Cellular location: Cytoplasm (By similarity): Q9WYW0; Nucleus: P02309
• Total number of polymer chains: 2
• Total formula weight: 28935.69

Authors

Cosgrove, M.S.,Wolberger, C. (deposition date: 2006-05-18, release date: 2006-12-05, Last modification date: 2023-11-15)

• Primary citation: Cosgrove, M.S.,Bever, K.,Avalos, J.L.,Muhammad, S.,Zhang, X.,Wolberger, C.; The structural basis of sirtuin substrate affinity; Biochemistry, 45:7511-7521, 2006; PubMed: 16768447; DOI: 10.1021/bi0526332

Experimental method

X-RAY DIFFRACTION (2.2 Å)