2H2H
The Structural basis of sirtuin substrate specificity
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | NAD-dependent deacetylase | polymer | 246 | 27569.8 | 1 | UniProt (Q9WYW0) Pfam (PF02146) In PDB | Thermotoga maritima | Regulatory protein SIR2 homolog |
| 2 | B | Histone H4 | polymer | 11 | 1300.5 | 1 | UniProt (P02309) In PDB | ||
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | water | water | 18.0 | 164 | Chemie (HOH) |
Sequence modifications
B: 7 - 17 (UniProt: P02309)
| PDB | External Database | Details |
|---|---|---|
| Aly 11 | Lys 79 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28870.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 28935.7 |
