2MNQ
 
 | | 1H, 13C, and 15N Chemical Shift Assignments for Thymosin alpha 1 | | Descriptor: | THYMOSIN ALPHA-1 | | Authors: | Nepravishta, R, Mandaliti, W, Eliseo, T, Sinibaldi Vallebona, P, Pica, F, Garaci, E, Paci, M. | | Deposit date: | 2014-04-09 | | Release date: | 2015-03-04 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Thymosin alpha 1 inserts N terminus into model membranes assuming a helical conformation.
Expert Opin Biol Ther, 15 Suppl 1, 2015
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1TJD
 | | The crystal structure of the reduced disulphide bond isomerase, DsbC, from Escherichia coli | | Descriptor: | Thiol:disulfide interchange protein dsbC | | Authors: | Banaszak, K, Mechin, I, Frost, G, Rypniewski, W. | | Deposit date: | 2004-06-04 | | Release date: | 2004-10-05 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of the reduced disulfide-bond isomerase DsbC from Escherichia coli.
Acta Crystallogr.,Sect.D, 60, 2004
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1TL2
 | | TACHYLECTIN-2 FROM TACHYPLEUS TRIDENTATUS (JAPANESE HORSESHOE CRAB) | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, PROTEIN (TACHYLECTIN-2) | | Authors: | Beisel, H.-G, Kawabata, S, Iwanaga, S, Huber, R, Bode, W. | | Deposit date: | 1998-12-14 | | Release date: | 1999-12-15 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Tachylectin-2: crystal structure of a specific GlcNAc/GalNAc-binding lectin involved in the innate immunity host defense of the Japanese horseshoe crab Tachypleus tridentatus.
EMBO J., 18, 1999
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3LPL
 | | E. coli pyruvate dehydrogenase complex E1 component E571A mutant | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, PHOSPHATE ION, ... | | Authors: | Furey, W. | | Deposit date: | 2010-02-05 | | Release date: | 2010-03-02 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Communication between thiamin cofactors in the Escherichia coli pyruvate dehydrogenase complex E1 component active centers: evidence for a "direct pathway" between the 4'-aminopyrimidine N1' atoms.
J.Biol.Chem., 285, 2010
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1SV2
 | | Crystal Structure of Peptide Deformylase from Leptospira Interrogans (LiPDF) at pH7.5 | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, FORMIC ACID, Peptide deformylase, ... | | Authors: | Zhou, Z, Song, X, Li, Y, Gong, W. | | Deposit date: | 2004-03-27 | | Release date: | 2005-08-09 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Novel conformational states of peptide deformylase from pathogenic bacterium Leptospira interrogans: implications for population shift
J.Biol.Chem., 280, 2005
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1ST8
 | | Crystal structure of fructan 1-exohydrolase IIa from Cichorium intybus | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Verhaest, M, Van den Ende, W, De Ranter, C.J, Van Laere, A, Rabijns, A. | | Deposit date: | 2004-03-25 | | Release date: | 2005-03-01 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | X-ray diffraction structure of a plant glycosyl hydrolase family 32 protein: fructan 1-exohydrolase IIa of Cichorium intybus.
Plant J., 41, 2005
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4P5B
 | | Crystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi bound with 5-Br dUMP | | Descriptor: | 5-BROMO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... | | Authors: | Li, Y, Chen, W, Li, J, Xia, Z, Deng, Z, Zhou, J. | | Deposit date: | 2014-03-15 | | Release date: | 2015-12-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.274 Å) | | Cite: | Crystal structure of a UMP/dUMP methylase PolB form Streptomyces cacaoi bound with 5-Br dUMP
To Be Published
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1SW1
 | | Crystal structure of ProX from Archeoglobus fulgidus in complex with proline betaine | | Descriptor: | 1,1-DIMETHYL-PROLINIUM, ZINC ION, osmoprotection protein (proX) | | Authors: | Schiefner, A, Holtmann, G, Diederichs, K, Welte, W, Bremer, E. | | Deposit date: | 2004-03-30 | | Release date: | 2004-09-14 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for the binding of compatible solutes by ProX from the hyperthermophilic archaeon Archaeoglobus fulgidus.
J.Biol.Chem., 279, 2004
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4PML
 | | Crystal Structure of human Tankyrase 2 in complex with 3-amino-benzamide. | | Descriptor: | 1,2-ETHANEDIOL, 3-aminobenzamide, DIMETHYL SULFOXIDE, ... | | Authors: | Qiu, W, Lam, R, Romanov, V, Gordon, R, Gebremeskel, S, Vodsedalek, J, Thompson, C, Beletskaya, I, Battaile, K.P, Pai, E.F, Chirgadze, N.Y. | | Deposit date: | 2014-05-22 | | Release date: | 2014-10-15 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Insights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2.
Acta Crystallogr.,Sect.D, 70, 2014
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4PNL
 | | Crystal structure of TNKS-2 in complex with DR2313. | | Descriptor: | 1,2-ETHANEDIOL, 2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one, DIMETHYL SULFOXIDE, ... | | Authors: | Qiu, W, Lam, R, Romanov, V, Gordon, R, Gebremeskel, S, Vodsedalek, J, Thompson, C, Beletskaya, I, Battaile, K.P, Pai, E.F, Chirgadze, N.Y. | | Deposit date: | 2014-05-23 | | Release date: | 2014-10-15 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Insights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2.
Acta Crystallogr.,Sect.D, 70, 2014
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2LUH
 | | NMR structure of the Vta1-Vps60 complex | | Descriptor: | Vacuolar protein sorting-associated protein VTA1, Vacuolar protein-sorting-associated protein 60 | | Authors: | Yang, Z, Vild, C, Ju, J, Zhang, X, Liu, J, Shen, J, Zhao, B, Lan, W, Gong, F, Liu, M, Cao, C, Xu, Z. | | Deposit date: | 2012-06-13 | | Release date: | 2012-11-07 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural Basis of Molecular Recognition between ESCRT-III-like Protein Vps60 and AAA-ATPase Regulator Vta1 in the Multivesicular Body Pathway.
J.Biol.Chem., 287, 2012
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4P9F
 | | E. coli McbR/YncC | | Descriptor: | HTH-type transcriptional regulator mcbR | | Authors: | Lord, D.M, Page, R, Peti, W. | | Deposit date: | 2014-04-03 | | Release date: | 2015-01-14 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.099 Å) | | Cite: | McbR/YncC: Implications for the Mechanism of Ligand and DNA Binding by a Bacterial GntR Transcriptional Regulator Involved in Biofilm Formation.
Biochemistry, 53, 2014
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1QZ7
 | | Beta-catenin binding domain of Axin in complex with beta-catenin | | Descriptor: | Axin, Beta-catenin | | Authors: | Xing, Y, Clements, W.K, Kimelman, D, Xu, W. | | Deposit date: | 2003-09-15 | | Release date: | 2003-11-18 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of a beta-catenin/Axin complex suggests a mechanism for the {beta}-catenin destruction complex
GENES DEV., 17, 2003
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6L2L
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1QYI
 | | X-RAY STRUCTURE OF Q8NW41 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ZR25. | | Descriptor: | hypothetical protein | | Authors: | Kuzin, A.P, Edstrom, W, Ma, L.C, Shin, L, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2003-09-10 | | Release date: | 2003-12-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | X-RAY STRUCTURE OF Q8NW41 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ZR25.
To be Published
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7CRP
 | | NSD3 bearing E1181K/T1232A dual mutation in complex with 187-bp NCP (1:1 binding mode) | | Descriptor: | DNA (168-MER), Histone H2A, Histone H2B, ... | | Authors: | Li, W, Tian, W, Yuan, G, Deng, P, Gozani, O, Patel, D, Wang, Z. | | Deposit date: | 2020-08-14 | | Release date: | 2020-10-21 | | Last modified: | 2021-03-03 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases.
Nature, 590, 2021
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3Q7K
 | | Formate Channel FocA from Salmonella typhimurium | | Descriptor: | FORMIC ACID, Probable formate transporter | | Authors: | Lue, W, Du, J, Wacker, T, Gerbig-Smentek, E, Andrade, S.L.A, Einsle, O. | | Deposit date: | 2011-01-05 | | Release date: | 2011-04-27 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | pH-dependent gating in a FocA formate channel
Science, 332, 2011
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1QZA
 | | Coordinates of the A/T site tRNA model fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome | | Descriptor: | Phe-tRNA | | Authors: | Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J. | | Deposit date: | 2003-09-16 | | Release date: | 2003-11-04 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (10 Å) | | Cite: | Incorporation of Aminoacyl-tRNA into the Ribosome as seen by Cryo-electron Microscopy
Nat.Struct.Biol., 10, 2003
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1X5O
 | | Solution structure of RRM domain in RNA binding motif, single-stranded interacting protein 1 | | Descriptor: | RNA binding motif, single-stranded interacting protein 1 | | Authors: | Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-05-16 | | Release date: | 2005-11-16 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of RRM domain in RNA binding motif, single-stranded interacting protein 1
To be Published
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4PBW
 | | Crystal structure of chicken receptor protein tyrosine phosphatase sigma in complex with TrkC | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NT-3 growth factor receptor, Protein-tyrosine phosphatase CRYPalpha1 isoform | | Authors: | Coles, C.H, Mitakidis, N, Zhang, P, Elegheert, J, Lu, W, Stoker, A.W, Nakagawa, T, Craig, A.M, Jones, E.Y, Aricescu, A.R. | | Deposit date: | 2014-04-14 | | Release date: | 2014-11-12 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Structural basis for extracellular cis and trans RPTP sigma signal competition in synaptogenesis.
Nat Commun, 5, 2014
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1QLM
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3LPA
 | | Crystal structure of a subtilisin-like protease | | Descriptor: | Acidic extracellular subtilisin-like protease AprV2, CALCIUM ION | | Authors: | Porter, C.J, Wong, W, Whisstock, J.C, Rood, J.I, Kennan, R.M. | | Deposit date: | 2010-02-05 | | Release date: | 2010-12-08 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates
Plos Pathog., 6, 2010
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7C8U
 | | The crystal structure of COVID-19 main protease in complex with GC376 | | Descriptor: | (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase | | Authors: | Luan, X, Shang, W, Wang, Y, Yin, W, Jiang, Y, Feng, S, Wang, Y, Liu, M, Zhou, R, Zhang, Z, Wang, F, Cheng, W, Gao, M, Wang, H, Wu, W, Tian, R, Tian, Z, Jin, Y, Jiang, H.W, Zhang, L, Xu, H.E, Zhang, S. | | Deposit date: | 2020-06-03 | | Release date: | 2020-06-24 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | The crystal structure of COVID-19 main protease in complex with GC376
To Be Published
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2M5S
 | | High-resolution NMR structure and cryo-EM imaging support multiple functional roles for the accessory I-domain of phage P22 coat protein | | Descriptor: | Coat protein | | Authors: | Rizzo, A.A, Suhanovsky, M.M, Baker, M.L, Fraser, L.C.R, Jones, L.M, Rempel, D.L, Gross, M.L, Chiu, W, Alexandrescu, A.T, Teschke, C.M. | | Deposit date: | 2013-03-05 | | Release date: | 2014-03-05 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Multiple Functional Roles of the Accessory I-Domain of Bacteriophage P22 Coat Protein Revealed by NMR Structure and CryoEM Modeling.
Structure, 22, 2014
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4DQQ
 | | Ternary complex of Bacillus DNA Polymerase I Large Fragment E658A, DNA duplex, and rCTP (paired with dG of template) in presence of Mg2+ | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CYTIDINE-5'-TRIPHOSPHATE, ... | | Authors: | Wang, W, Beese, L.S. | | Deposit date: | 2012-02-16 | | Release date: | 2012-06-06 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.595 Å) | | Cite: | Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
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