4I79
 
 | | Crystal structure of human NUP43 | | 分子名称: | Nucleoporin Nup43, UNKNOWN ATOM OR ION, floating chain, ... | | 著者 | Xu, C, Tempel, W, Li, Z, He, H, Wernimont, A.K, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2012-11-30 | | 公開日 | 2013-02-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of human nuclear pore complex component NUP43.
Febs Lett., 589, 2015
|
|
4GVJ
 | | Tyk2 (JH1) in complex with adenosine di-phosphate | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Non-receptor tyrosine-protein kinase TYK2 | | 著者 | Liang, J, Abbema, A.V, Bao, L, Barrett, K, Beresini, M, Berezhkovskiy, L, Blair, W, Chang, C, Driscoll, J, Eigenbrot, C, Ghilardi, N, Gibbons, P, Halladay, J, Johnson, A, Kohli, P.B, Lai, Y, Liimatta, M, Mantik, P, Menghrajani, K, Murray, J, Sambrone, A, Shao, Y, Shia, S, Shin, Y, Smith, J, Sohn, S, Stanley, M, Tsui, V, Ultsch, M, Wu, L, Zhang, B, Magnuson, S. | | 登録日 | 2012-08-30 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Lead identification of novel and selective TYK2 inhibitors.
Eur.J.Med.Chem., 67, 2013
|
|
4IFH
 | | Crystal structure of human insulin degrading enzyme (IDE) in complex with compound BDM44619 | | 分子名称: | Insulin-degrading enzyme, N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-4-yl}methyl)-4-methylbenzamide, ZINC ION | | 著者 | Liang, W.G, Guo, Q, Deprez, R, Deprez, B, Tang, W. | | 登録日 | 2012-12-14 | | 公開日 | 2013-12-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.286 Å) | | 主引用文献 | Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice.
Nat Commun, 6, 2015
|
|
4IMB
 | |
4IG4
 | | Crystal structure of single mutant thermostable NPPase (N86S) from Geobacillus stearothermophilus | | 分子名称: | Thermostable NPPase | | 著者 | Guo, Z, Wang, F, Huang, J, Qiu, R, Yang, Z, Wang, Y, Gong, W, Ji, C. | | 登録日 | 2012-12-16 | | 公開日 | 2013-12-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | | 主引用文献 | Crystal structure of thermostable NPPase from Geobacillus stearothermophilus
To be Published
|
|
4HGV
 | | Crystal structure of a fumarate hydratase | | 分子名称: | Fumarate hydratase class II, SULFATE ION | | 著者 | Eswaramoorthy, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2012-10-08 | | 公開日 | 2012-10-31 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Crystal structure of a fumarate hydratase
To be Published
|
|
4FU6
 | | Crystal structure of the PSIP1 PWWP domain | | 分子名称: | GLYCEROL, PC4 and SFRS1-interacting protein, SULFATE ION, ... | | 著者 | Qin, S, Tempel, W, Xu, C, Wu, H, Dong, A, Cerovina, T, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2012-06-28 | | 公開日 | 2012-08-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure and function of the nucleosome-binding PWWP domain.
Trends Biochem.Sci., 39, 2014
|
|
4IYG
 | |
4J2U
 | | Crystal structure of an enoyl-CoA hydratase from Rhodobacter sphaeroides 2.4.1 | | 分子名称: | Enoyl-CoA hydratase | | 著者 | Kumaran, D, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Al Obaidi, N, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2013-02-05 | | 公開日 | 2013-02-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of an enoyl-CoA hydratase from Rhodobacter sphaeroides 2.4.1
To be Published
|
|
4HY3
 | | Crystal structure of a phosphoglycerate oxidoreductase from rhizobium etli | | 分子名称: | phosphoglycerate oxidoreductase | | 著者 | Kumaran, D, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2012-11-12 | | 公開日 | 2012-12-12 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of a phosphoglycerate oxidoreductase from rhizobium etli
To be Published
|
|
4J3C
 | | Crystal structure of 16S ribosomal RNA methyltransferase RsmE | | 分子名称: | Ribosomal RNA small subunit methyltransferase E | | 著者 | Eswaramoorthy, S, Chamala, S, Evans, B, Foti, F, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Al Obaidi, N, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2013-02-05 | | 公開日 | 2013-02-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of 16S ribosomal RNA methyltransferase RsmE
TO BE PUBLISHED
|
|
4IVM
 | |
4HSG
 | | Crystal structure of human PRMT3 in complex with an allosteric inhibitor (PRMT3- KTD) | | 分子名称: | 1-(1,2,3-benzothiadiazol-6-yl)-3-(2-oxo-2-phenylethyl)urea, PRMT3 protein, UNKNOWN ATOM OR ION | | 著者 | Dobrovetsky, E, Dong, A, Liu, F, Li, F, Tempel, W, Siarheyeva, A, Hajian, T, Smil, D, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Schapira, M, Jin, J, Vedadi, M, Structural Genomics Consortium (SGC) | | 登録日 | 2012-10-30 | | 公開日 | 2012-12-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors.
J. Med. Chem., 56, 2013
|
|
4JFC
 | | Crystal structure of a enoyl-CoA hydratase from Polaromonas sp. JS666 | | 分子名称: | Enoyl-CoA hydratase, GLYCEROL | | 著者 | Kumaran, D, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Al Obaidi, N, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2013-02-28 | | 公開日 | 2013-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal structure of a enoyl-CoA hydratase from Polaromonas sp. JS666
To be Published
|
|
4JCU
 | | Crystal structure of a 5-carboxymethyl-2-hydroxymuconate isomerase from Deinococcus radiodurans R1 | | 分子名称: | 5-carboxymethyl-2-hydroxymuconate isomerase | | 著者 | Kumaran, D, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Al Obaidi, N, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2013-02-22 | | 公開日 | 2013-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of a 5-carboxymethyl-2-hydroxymuconate isomerase from Deinococcus radiodurans R1
To be Published
|
|
4IVO
 | |
4JLR
 | | Crystal structure of a designed Respiratory Syncytial Virus Immunogen in complex with Motavizumab | | 分子名称: | Motavizumab Fab heavy chain, Motavizumab Fab light chain, PENTAETHYLENE GLYCOL, ... | | 著者 | Rupert, P.B, Correia, B, Schief, W, Strong, R.K. | | 登録日 | 2013-03-12 | | 公開日 | 2014-02-05 | | 最終更新日 | 2014-12-17 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Proof of principle for epitope-focused vaccine design.
Nature, 507, 2014
|
|
4JJ9
 | | Crystal Structure of 5-carboxymethyl-2-hydroxymuconate delta-isomerase | | 分子名称: | 5-carboxymethyl-2-hydroxymuconate delta-isomerase, SULFATE ION | | 著者 | Eswaramoorthy, S, Chamala, S, Evans, B, Foti, F, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Al Obaidi, N, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2013-03-07 | | 公開日 | 2013-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Crystal Structure of 5-carboxymethyl-2-hydroxymuconate delta-isomerase
To be Published
|
|
4HHO
 | | Serum paraoxonase-1 by directed evolution with the H115W mutation | | 分子名称: | BROMIDE ION, CALCIUM ION, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Moshe, B.-D, Grzegorz, W, Mikael, E, Israel, S, Joel, L.S, Dan, S.T. | | 登録日 | 2012-10-10 | | 公開日 | 2013-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Catalytic metal ion rearrangements underline promiscuity and evolvability of a metalloenzyme.
J.Mol.Biol., 425, 2013
|
|
4JOT
 | | Crystal structure of enoyl-CoA hydrotase from Deinococcus radiodurans R1 | | 分子名称: | Enoyl-CoA hydratase, putative, GLYCEROL | | 著者 | Eswaramoorthy, S, Chamala, S, Evans, B, Foti, F, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Al Obaidi, N, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2013-03-18 | | 公開日 | 2013-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Crystal structure of enoyl-CoA hydrotase from Deinococcus radiodurans R1
To be Published
|
|
4JRH
 | | Crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Vibrio Cholerae (space group P43) at 2.2 Angstrom | | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 2, ACETATE ION | | 著者 | Hou, J, Chruszcz, M, Shabalin, I.G, Zheng, H, Cooper, D.R, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2013-03-21 | | 公開日 | 2013-04-03 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 |
|
|
4JCS
 | | Crystal structure of Enoyl-CoA hydratase/isomerase from Cupriavidus metallidurans CH34 | | 分子名称: | Enoyl-CoA hydratase/isomerase | | 著者 | Eswaramoorthy, S, Chamala, S, Chamala, B, Foti, F, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Al Obaidi, N, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2013-02-22 | | 公開日 | 2013-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Crystal structure of Enoyl-CoA hydratase/isomerase from Cupriavidus metallidurans CH34
To be Published
|
|
4IA9
 | | Crystal structure of human WD REPEAT DOMAIN 5 in complex with 2-chloro-4-fluoro-3-methyl-N-[2-(4-methylpiperazin-1-yl)-5-nitrophenyl]benzamide | | 分子名称: | 1,2-ETHANEDIOL, 2-chloro-4-fluoro-3-methyl-N-[2-(4-methylpiperazin-1-yl)-5-nitrophenyl]benzamide, UNKNOWN ATOM OR ION, ... | | 著者 | Dong, A, Dombrovski, L, Bolshan, Y, Getlik, M, Tempel, W, Kuznetsova, E, Wasney, G.A, Hajian, T, Poda, G, Nguyen, K.T, Schapira, M, Brown, P.J, Al-awar, R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Smil, D, Vedadi, M, Wu, H, Structural Genomics Consortium (SGC) | | 登録日 | 2012-12-06 | | 公開日 | 2012-12-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Synthesis, Optimization, and Evaluation of Novel Small Molecules as Antagonists of WDR5-MLL Interaction.
ACS Med Chem Lett, 4, 2013
|
|
4HUJ
 | | Crystal structure of a hypothetical protein SMa0349 from Sinorhizobium meliloti | | 分子名称: | Uncharacterized protein | | 著者 | Rice, S, Eswaramoorthy, S, Chamala, S, Evans, B, Foti, F, Gizzi, A, Hillerich, B, Kar, A, LaFleur, J, Seidel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2012-11-02 | | 公開日 | 2012-12-12 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Crystal structure of a hypothetical protein SMa0349 from Sinorhizobium meliloti
To be Published
|
|
4JYA
 | | Crystal structures of pseudouridinilated stop codons with ASLs | | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Fernandez, I.S, Ng, C.L, Kelley, A.C, Guowei, W, Yu, Y.T, Ramakrishnan, V. | | 登録日 | 2013-03-29 | | 公開日 | 2013-06-26 | | 最終更新日 | 2013-08-21 | | 実験手法 | X-RAY DIFFRACTION (3.098 Å) | | 主引用文献 | Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
|
|
