8YC0
 
 | | T cell receptor V delta2 V gamma9 in GDN | | 分子名称: | CHOLESTEROL, T cell receptor delta variable 2,T cell receptor delta constant, T cell receptor gamma variable 9,T cell receptor gamma constant 1, ... | | 著者 | Xin, W, Huang, B, Chi, X, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. | | 登録日 | 2024-02-17 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (4.12 Å) | | 主引用文献 | Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 630, 2024
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8WY0
 | | T cell receptor delta 2 gamma 9 with F283A, F290A, and F291A | | 分子名称: | CHOLESTEROL, Signal peptide,flag tag,T cell receptor delta variable 2,T cell receptor delta constant, Signal peptide,flag tag,T cell receptor gamma variable 9,T cell receptor gamma constant 1, ... | | 著者 | Xin, W, Huang, B, Chi, X, Liu, Y, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. | | 登録日 | 2023-10-30 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 630, 2024
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9F9K
 | | Crystal structure of MUS81-EME1 bound by compound 15. | | 分子名称: | 5-oxidanyl-6-oxidanylidene-2-(4-phenylphenyl)-1H-pyrimidine-4-carboxylic acid, Crossover junction endonuclease EME1, Crossover junction endonuclease MUS81, ... | | 著者 | Collie, G.W. | | 登録日 | 2024-05-07 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-07-31 | | 実験手法 | X-RAY DIFFRACTION (2.728 Å) | | 主引用文献 | Fragment-Based Discovery of Novel MUS81 Inhibitors.
Acs Med.Chem.Lett., 15, 2024
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9B8Z
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8WP0
 | | Structure of the Arabidopsis E529Q/E1174Q ABCB19 in the ATP bound state | | 分子名称: | ABC transporter B family member 19, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | | 著者 | Ying, W, Wei, H, Liu, X, Sun, L. | | 登録日 | 2023-10-08 | | 公開日 | 2024-03-13 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export.
Science, 383, 2024
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8WYI
 | | T cell receptor delta 2 gamma 9 with TCRD TM domain chimera of TRAC | | 分子名称: | Signal peptide,flag tag,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant, Signal peptide,flag tag,T cell receptor gamma variable 9,T cell receptor gamma constant 1,T cell receptor gamma variable 9,T cell receptor gamma constant 1, T-cell surface glycoprotein CD3 delta chain, ... | | 著者 | Xin, W, Huang, B, Chi, X, Liu, Y, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. | | 登録日 | 2023-10-31 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 630, 2024
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4B8W
 | | Crystal structure of human GDP-L-fucose synthase with bound NADP and GDP, tetragonal crystal form | | 分子名称: | GDP-L-FUCOSE SYNTHASE, GUANOSINE-5'-DIPHOSPHATE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Vollmar, M, Krojer, T, Shafqat, N, Rojkova, A, Bunkoczi, G, Pike, A, Chaikuat, A, Carpenter, E, Yue, W.W, Kavanagh, K, von Delft, F, Weigelt, J, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U. | | 登録日 | 2012-08-31 | | 公開日 | 2012-11-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Crystal Structure of Human Gdp-L-Fucose Synthase with Bound Nadp and Gdp, Tetragonal Crystal Form
To be Published
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8YR3
 | | Cryo-EM structure of the human ABCB6 in complex with Cd(II):GSH | | 分子名称: | ATP-binding cassette sub-family B member 6, CADMIUM ION, GLUTATHIONE | | 著者 | Choi, S.H, Lee, S.S, Lee, H.Y, Kim, S, Kim, J.W, Jin, M.S. | | 登録日 | 2024-03-20 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structure of cadmium-bound human ABCB6.
Commun Biol, 7, 2024
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8WXE
 | | Vgamma5Vdelta1 EH TCR-CD3 complex | | 分子名称: | CHOLESTEROL, Signal peptide,flag tag,T cell receptor delta variable 1,T cell receptor delta constant, Signal peptide,flag tag,T cell receptor gamma variable 5,T cell receptor gamma constant 1, ... | | 著者 | Xin, W, Huang, B, Chi, X, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. | | 登録日 | 2023-10-28 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 630, 2024
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9B92
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9FFG
 | | Empty capsid of Rhodobacter microvirus Ebor computed with I4 symmetry | | 分子名称: | Major capsid protein | | 著者 | Bardy, P, MacDonald, C.I.W, Jenkins, H.T, Byrom, L, Chechik, M, Hart, S.J, Turkenburg, J.P, Blaza, J.N, Fogg, P.C.M, Antson, A.A. | | 登録日 | 2024-05-23 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A stargate mechanism of Microviridae genome delivery unveiled by cryogenic electron tomography.
Biorxiv, 2024
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8WWO
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3VD9
 | | E. coli (lacZ) beta-galactosidase (N460S) in complex with IPTG | | 分子名称: | 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | | 著者 | Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E. | | 登録日 | 2012-01-04 | | 公開日 | 2012-04-11 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
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8YGY
 | | Structure of the KLK1 from Biortus. | | 分子名称: | 1,2-ETHANEDIOL, Kallikrein-1, SULFATE ION, ... | | 著者 | Wang, F, Cheng, W, Lv, Z, Meng, Q, Xu, Y. | | 登録日 | 2024-02-27 | | 公開日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | | 主引用文献 | Structure of the KLK1 from Biortus.
To Be Published
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8YUV
 | | Cryo-EM structure of the immepip-bound H3R-Gi complex | | 分子名称: | 4-(1H-imidazol-5-ylmethyl)piperidine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y. | | 登録日 | 2024-03-27 | | 公開日 | 2024-06-05 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs.
Adv Sci, 11, 2024
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8ZH8
 | | Human GPR103 -Gq complex bound to QRFP26 | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,Guanine nucleotide-binding protein G(i) subunit alpha-2,Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Iwama, A, Akasaka, H, Sano, F.K, Oshima, H.S, Shihoya, W, Nureki, O. | | 登録日 | 2024-05-10 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | | 主引用文献 | Structure and dynamics of the pyroglutamylated RF-amide peptide QRFP receptor GPR103.
Nat Commun, 15, 2024
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9B8W
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3VCD
 | | Computationally Designed Self-assembling Octahedral Cage protein, O333, Crystallized in space group R32 | | 分子名称: | CHLORIDE ION, Propanediol utilization polyhedral body protein PduT, SULFATE ION | | 著者 | Sawaya, M.R, King, N.P, Sheffler, W, Baker, D, Yeates, T.O. | | 登録日 | 2012-01-03 | | 公開日 | 2012-06-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Computational design of self-assembling protein nanomaterials with atomic level accuracy.
Science, 336, 2012
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8YUU
 | | Cryo-EM structure of the histamine-bound H3R-Gi complex | | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y. | | 登録日 | 2024-03-27 | | 公開日 | 2024-06-05 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs.
Adv Sci, 11, 2024
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9EXX
 | | Crystal structure of the PWWP1 domain of NSD2 bound by compound 18. | | 分子名称: | 1,2-ETHANEDIOL, 4-methyl-3-[1-methyl-5-(3-oxidanylidene-4~{H}-1,4-benzoxazin-7-yl)imidazol-4-yl]-~{N}-phenyl-benzamide, ETHANOL, ... | | 著者 | Collie, G.W. | | 登録日 | 2024-04-09 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.943 Å) | | 主引用文献 | Identification of Novel Potent NSD2-PWWP1 Ligands Using Structure-Based Design and Computational Approaches.
J.Med.Chem., 67, 2024
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3VDC
 | | E. coli (lacZ) beta-galactosidase (N460T) in complex with IPTG | | 分子名称: | 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | | 著者 | Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E. | | 登録日 | 2012-01-04 | | 公開日 | 2012-04-11 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
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8YGX
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8XOT
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8YHS
 | | The Crystal Structure of BRDT from Biortus. | | 分子名称: | 1,2-ETHANEDIOL, 2,4-dimethyl-6-[6-(oxan-4-yl)-1-[(1~{S})-1-phenylethyl]imidazo[4,5-c]pyridin-2-yl]pyridazin-3-one, Bromodomain testis-specific protein | | 著者 | Wang, F, Cheng, W, Lv, Z, Meng, Q, Lu, Y. | | 登録日 | 2024-02-28 | | 公開日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The Crystal Structure of BRDT from Biortus.
To Be Published
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9B3Q
 | | The structure of the human cardiac F-actin mutant A331P | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... | | 著者 | Doran, M.H, Sousa, D, Rynkiewicz, M.J, Lehman, W, Cammarato, A. | | 登録日 | 2024-03-20 | | 公開日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure of human cardiac actin
To Be Published
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