8ZH8

Human GPR103 -Gq complex bound to QRFP26

Summary for 8ZH8

Entry DOI	10.2210/pdb8zh8/pdb
EMDB information	60096
Descriptor	Pyroglutamylated RF-amide peptide receptor, nanobody Nb35, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (7 entities in total)
Functional Keywords	gpcr, membrane protein, membrane protein-immune system complex, membrane protein/immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	7
Total formula weight	174089.31
Authors	Iwama, A.,Akasaka, H.,Sano, F.K.,Oshima, H.S.,Shihoya, W.,Nureki, O. (deposition date: 2024-05-10, release date: 2024-07-03)
Primary citation	Iwama, A.,Kise, R.,Akasaka, H.,Sano, F.K.,Oshima, H.S.,Inoue, A.,Shihoya, W.,Nureki, O. Structure and dynamics of the pyroglutamylated RF-amide peptide QRFP receptor GPR103. Nat Commun, 15:4769-4769, 2024 Cited by PubMed: 38897996 DOI: 10.1038/s41467-024-49030-5 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.19 Å)

Structure validation