8D5A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8d5a by Molmil](/molmil-images/mine/8d5a) | Middle state of SARS-CoV-2 BA.2 variant spike protein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, J, Tang, W.C, Gao, H.L, Shi, W, Peng, H.Q, Volloch, S.R, Xiao, T.S, Chen, B. | 登録日 | 2022-06-04 | 公開日 | 2023-06-07 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural and functional characteristics of the SARS-CoV-2 Omicron subvariant BA.2 spike protein. Nat.Struct.Mol.Biol., 30, 2023
|
|
7RZI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rzi by Molmil](/molmil-images/mine/7rzi) | Insulin Degrading Enzyme pC/pC | 分子名称: | Cysteine-free Insulin-degrading enzyme, Insulin A chain, Insulin B chain | 著者 | Mancl, J.M, Liang, W.G, Tang, W.J. | 登録日 | 2021-08-27 | 公開日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme To be published
|
|
7RZH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rzh by Molmil](/molmil-images/mine/7rzh) | Insulin Degrading Enzyme O/O | 分子名称: | Cysteine-free Insulin-degrading enzyme | 著者 | Mancl, J.M, Liang, W.G, Tang, W.J. | 登録日 | 2021-08-27 | 公開日 | 2022-08-31 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme To be published
|
|
7RZE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rze by Molmil](/molmil-images/mine/7rze) | Insulin Degrading Enzyme pO/pC | 分子名称: | Cysteine-free Insulin-degrading enzyme, Insulin A chain, Insulin B chain | 著者 | Mancl, J.M, Liang, W.G, Tang, W.J. | 登録日 | 2021-08-27 | 公開日 | 2022-08-31 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme To be published
|
|
7RZF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rzf by Molmil](/molmil-images/mine/7rzf) | Insulin Degrading Enzyme O/pC | 分子名称: | Cysteine-free Insulin-degrading enzyme, Insulin A chain, Insulin B chain | 著者 | Mancl, J.M, Liang, W.G, Tang, W.J. | 登録日 | 2021-08-27 | 公開日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme To be published
|
|
7RZG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rzg by Molmil](/molmil-images/mine/7rzg) | Insulin Degrading Enzyme O/pO | 分子名称: | Cysteine-free Insulin-degrading enzyme | 著者 | Mancl, J.M, Liang, W.G, Tang, W.J. | 登録日 | 2021-08-27 | 公開日 | 2022-08-31 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme To be published
|
|
3KBX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3kbx by Molmil](/molmil-images/mine/3kbx) | |
8EZL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ezl by Molmil](/molmil-images/mine/8ezl) | Pfs25 in complex with transmission-reducing antibody AS01-50 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 25 kDa ookinete surface antigen, Transmission-reducing antibody AS01-50, ... | 著者 | Shukla, N, Tang, W.K, Tolia, N.H. | 登録日 | 2022-11-01 | 公開日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A human antibody epitope map of the malaria vaccine antigen Pfs25. Npj Vaccines, 8, 2023
|
|
8EZM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ezm by Molmil](/molmil-images/mine/8ezm) | Pfs25 in complex with transmission-reducing antibody AS01-63 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 25 kDa ookinete surface antigen, SULFATE ION, ... | 著者 | Shukla, N, Tang, W.K, Tolia, N.H. | 登録日 | 2022-11-01 | 公開日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A human antibody epitope map of the malaria vaccine antigen Pfs25. Npj Vaccines, 8, 2023
|
|
8EZK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ezk by Molmil](/molmil-images/mine/8ezk) | |
8DFI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dfi by Molmil](/molmil-images/mine/8dfi) | |
8JPP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jpp by Molmil](/molmil-images/mine/8jpp) | Cryo-EM structure of succinate receptor bound to succinate acid coupling MiniGsq | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Wang, T.X, Tang, W.Q, Li, F.H, Wang, J.Y. | 登録日 | 2023-06-12 | 公開日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Molecular activation and G protein coupling selectivity of human succinate receptor SUCR1. Cell Res., 2024
|
|
8J22
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8j22 by Molmil](/molmil-images/mine/8j22) | Cryo-EM structure of FFAR2 complex bound with TUG-1375 | 分子名称: | (2R,4R)-2-(2-chlorophenyl)-3-[4-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]carbonyl-1,3-thiazolidine-4-carboxylic acid, Free fatty acid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Tai, L, Li, F, Sun, X, Tang, W, Wang, J. | 登録日 | 2023-04-14 | 公開日 | 2024-01-24 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Molecular recognition and activation mechanism of short-chain fatty acid receptors FFAR2/3. Cell Res., 34, 2024
|
|
8J24
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8j24 by Molmil](/molmil-images/mine/8j24) | Cryo-EM structure of FFAR2 complex bound with acetic acid | 分子名称: | ACETATE ION, Free fatty acid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Tai, L, Li, F, Tang, W, Sun, X, Wang, J. | 登録日 | 2023-04-14 | 公開日 | 2024-01-24 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Molecular recognition and activation mechanism of short-chain fatty acid receptors FFAR2/3. Cell Res., 34, 2024
|
|
8J20
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8j20 by Molmil](/molmil-images/mine/8j20) | Cryo-EM structure of FFAR3 bound with valeric acid and AR420626 | 分子名称: | (4R)-N-[2,5-bis(chloranyl)phenyl]-4-(furan-2-yl)-2-methyl-5-oxidanylidene-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide, Free fatty acid receptor 3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Tai, L, Li, F, Sun, X, Tang, W, Wang, J. | 登録日 | 2023-04-14 | 公開日 | 2024-01-24 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Molecular recognition and activation mechanism of short-chain fatty acid receptors FFAR2/3. Cell Res., 34, 2024
|
|
8J21
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8j21 by Molmil](/molmil-images/mine/8j21) | Cryo-EM structure of FFAR3 complex bound with butyrate acid | 分子名称: | Free fatty acid receptor 3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Tai, L, Li, F, Sun, X, Tang, W, Wang, J. | 登録日 | 2023-04-14 | 公開日 | 2024-01-24 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular recognition and activation mechanism of short-chain fatty acid receptors FFAR2/3. Cell Res., 34, 2024
|
|
8JPN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jpn by Molmil](/molmil-images/mine/8jpn) | Cryo-EM structure of succinate receptor bound to cis-epoxysuccinic acid coupling to Gi | 分子名称: | (2R,3S)-oxirane-2,3-dicarboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Wang, T.X, Tang, W.Q, Li, F.H, Wang, J.Y. | 登録日 | 2023-06-12 | 公開日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Molecular activation and G protein coupling selectivity of human succinate receptor SUCR1. Cell Res., 2024
|
|
8GYC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gyc by Molmil](/molmil-images/mine/8gyc) | Annexin A5 protein dimer mutant | 分子名称: | Annexin A5, CALCIUM ION | 著者 | Hua, Z.C, Tang, W. | 登録日 | 2022-09-22 | 公開日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | structure dissection of the membrane aggregation mechanism induced by Annexin A5 mutation To Be Published
|
|
5L2U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5l2u by Molmil](/molmil-images/mine/5l2u) | |
8H0J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8h0j by Molmil](/molmil-images/mine/8h0j) | Annexin A5 mutant | 分子名称: | Annexin A5, CALCIUM ION | 著者 | Hua, Z.C, Tang, W. | 登録日 | 2022-09-29 | 公開日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | structure dissection of the membrane aggregation mechanism induced by Annexin A5 mutation To Be Published
|
|
8H9Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8h9z by Molmil](/molmil-images/mine/8h9z) | Annexin A5 protein mutant | 分子名称: | Annexin A5, CALCIUM ION | 著者 | Hua, Z.C, Tang, W. | 登録日 | 2022-10-26 | 公開日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | structure dissection of the membrane aggregation mechanism induced by Annexin A5 mutation To Be Published
|
|
4Y72
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4y72 by Molmil](/molmil-images/mine/4y72) | Human CDK1/CyclinB1/CKS2 With Inhibitor | 分子名称: | Cyclin-dependent kinase 1, Cyclin-dependent kinases regulatory subunit 2, G2/mitotic-specific cyclin-B1, ... | 著者 | Brown, N.R, Korolchuk, S, Martin, M.P, Stanley, W, Moukhametzianov, R, Noble, M.E.M, Endicott, J.A. | 登録日 | 2015-02-13 | 公開日 | 2015-08-12 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | CDK1 structures reveal conserved and unique features of the essential cell cycle CDK. Nat Commun, 6, 2015
|
|
4YC3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yc3 by Molmil](/molmil-images/mine/4yc3) | CDK1/CyclinB1/CKS2 Apo | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cyclin-dependent kinase 1, Cyclin-dependent kinases regulatory subunit 2, ... | 著者 | Brown, N.R, Korolchuk, S, Martin, M.P, Stanley, W, Moukhametzianov, R, Noble, M.E.M, Endicott, J.A. | 登録日 | 2015-02-19 | 公開日 | 2016-04-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | CDK1 structures reveal conserved and unique features of the essential cell cycle CDK. Nat Commun, 6, 2015
|
|
4YC6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yc6 by Molmil](/molmil-images/mine/4yc6) | CDK1/CKS1 | 分子名称: | Cyclin-dependent kinase 1, Cyclin-dependent kinases regulatory subunit 1 | 著者 | Brown, N.R, Korolchuk, S, Martin, M.P, Stanley, W, Moukhametzianov, R, Noble, M.E.M, Endicott, J.A. | 登録日 | 2015-02-19 | 公開日 | 2015-05-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | CDK1 structures reveal conserved and unique features of the essential cell cycle CDK. Nat Commun, 6, 2015
|
|
6XOS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xos by Molmil](/molmil-images/mine/6xos) | |