8EZL

Pfs25 in complex with transmission-reducing antibody AS01-50

Summary for 8EZL

• Entry DOI: 10.2210/pdb8ezl/pdb
• Descriptor: 25 kDa ookinete surface antigen, Transmission-reducing antibody AS01-50, single chain Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: pfs25, transmission-blocking vaccine, immune system
• Biological source: Plasmodium falciparum NF54; More
• Total number of polymer chains: 2
• Total formula weight: 49976.13

Authors

Shukla, N.,Tang, W.K.,Tolia, N.H. (deposition date: 2022-11-01, release date: 2023-08-16)

• Primary citation: Shukla, N.,Tang, W.K.,Coelho, C.H.,Long, C.A.,Healy, S.A.,Sagara, I.,Miura, K.,Duffy, P.E.,Tolia, N.H.; A human antibody epitope map of the malaria vaccine antigen Pfs25.; Npj Vaccines, 8:108-108, 2023; PubMed: 37542029; DOI: 10.1038/s41541-023-00712-z

Experimental method

X-RAY DIFFRACTION (2.3 Å)