8EZL

Pfs25 in complex with transmission-reducing antibody AS01-50

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	25 kDa ookinete surface antigen	polymer	182	20033.1	1	UniProt (P13829) Pfam (PF06247) In PDB	Plasmodium falciparum NF54	Pfs25
2	H	Transmission-reducing antibody AS01-50, single chain Fv	polymer	280	29721.8	1		Plasmodium falciparum NF54
3	H	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
4		water	water		18.0	54	Chemie (HOH)

Sequence modifications

A: 1 - 171 (UniProt: P13829)

PDB	External Database	Details
Thr -1	-	expression tag
Gly 0	-	expression tag
Gln 90	Asn 112	conflict
Gln 143	Asn 165	conflict
Gln 165	Asn 187	conflict
Gly 172	-	expression tag
Thr 173	-	expression tag
Lys 174	-	expression tag
His 175	-	expression tag
His 176	-	expression tag
His 177	-	expression tag
His 178	-	expression tag
His 179	-	expression tag
His 180	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	49754.9
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	49976.1

*Water molecules are not included.