8EZL
Pfs25 in complex with transmission-reducing antibody AS01-50
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 25 kDa ookinete surface antigen | polymer | 182 | 20033.1 | 1 | UniProt (P13829) | Plasmodium falciparum NF54 | Pfs25 |
| 2 | B (H) | Transmission-reducing antibody AS01-50, single chain Fv | polymer | 280 | 29721.8 | 1 | Plasmodium falciparum NF54 | ||
| 3 | C (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 4 | D, E (A, H) | water | water | 18.0 | 54 | Chemie (HOH) |
Sequence modifications
A: 1 - 171 (UniProt: P13829)
| PDB | External Database | Details |
|---|---|---|
| Thr -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Gln 90 | Asn 112 | conflict |
| Gln 143 | Asn 165 | conflict |
| Gln 165 | Asn 187 | conflict |
| Gly 172 | - | expression tag |
| Thr 173 | - | expression tag |
| Lys 174 | - | expression tag |
| His 175 | - | expression tag |
| His 176 | - | expression tag |
| His 177 | - | expression tag |
| His 178 | - | expression tag |
| His 179 | - | expression tag |
| His 180 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49754.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 49976.1 |
