8JPP

Cryo-EM structure of succinate receptor bound to succinate acid coupling MiniGsq

Summary for 8JPP

Entry DOI	10.2210/pdb8jpp/pdb
EMDB information	36486
Descriptor	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (5 entities in total)
Functional Keywords	complex, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	153273.73
Authors	Wang, T.X.,Tang, W.Q.,Li, F.H.,Wang, J.Y. (deposition date: 2023-06-12, release date: 2024-05-22, Last modification date: 2024-11-20)
Primary citation	Wang, T.,Tang, W.,Zhu, X.,Lv, Z.,Chen, J.,Li, Y.,Sun, X.,Lv, H.,Gu, Q.,Li, F.,Wang, J. Molecular activation and G protein coupling selectivity of human succinate receptor SUCR1. Cell Res., 34:590-593, 2024 Cited by PubMed: 38744983 DOI: 10.1038/s41422-024-00968-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation