4Y72

Human CDK1/CyclinB1/CKS2 With Inhibitor

Summary for 4Y72

• Entry DOI: 10.2210/pdb4y72/pdb
• Descriptor: Cyclin-dependent kinase 1, G2/mitotic-specific cyclin-B1, Cyclin-dependent kinases regulatory subunit 2, ... (5 entities in total)
• Functional Keywords: cdk1, cyclinb1, cks2, inhibitor, transferase
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus: P06493; Cytoplasm: P14635
• Total number of polymer chains: 3
• Total formula weight: 76574.67

Authors

Brown, N.R.,Korolchuk, S.,Martin, M.P.,Stanley, W.,Moukhametzianov, R.,Noble, M.E.M.,Endicott, J.A. (deposition date: 2015-02-13, release date: 2015-08-12, Last modification date: 2024-01-10)

• Primary citation: Brown, N.R.,Korolchuk, S.,Martin, M.P.,Stanley, W.A.,Moukhametzianov, R.,Noble, M.E.,Endicott, J.A.; CDK1 structures reveal conserved and unique features of the essential cell cycle CDK.; Nat Commun, 6:6769-6769, 2015; PubMed: 25864384; DOI: 10.1038/ncomms7769

Experimental method

X-RAY DIFFRACTION (2.3 Å)