8EZK

Pfs25 in complex with transmission-reducing antibody AS01-04

Summary for 8EZK

• Entry DOI: 10.2210/pdb8ezk/pdb
• Descriptor: 25 kDa ookinete surface antigen, Transmission-reducing antibody AS01-4, single-chain Fv (3 entities in total)
• Functional Keywords: pfs25, transmission-blocking vaccine, immune system
• Biological source: Plasmodium falciparum (isolate NF54); More
• Total number of polymer chains: 4
• Total formula weight: 95170.81

Authors

Shukla, N.,Tang, W.K.,Tolia, N.H. (deposition date: 2022-11-01, release date: 2023-08-16)

• Primary citation: Shukla, N.,Tang, W.K.,Coelho, C.H.,Long, C.A.,Healy, S.A.,Sagara, I.,Miura, K.,Duffy, P.E.,Tolia, N.H.; A human antibody epitope map of the malaria vaccine antigen Pfs25.; Npj Vaccines, 8:108-108, 2023; PubMed: 37542029; DOI: 10.1038/s41541-023-00712-z

Experimental method

X-RAY DIFFRACTION (2.3 Å)