8J22

Cryo-EM structure of FFAR2 complex bound with TUG-1375

Summary for 8J22

Entry DOI	10.2210/pdb8j22/pdb
EMDB information	35942
Descriptor	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, Free fatty acid receptor 2, ... (6 entities in total)
Functional Keywords	ffar2, complex, gpcr, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	156830.14
Authors	Tai, L.,Li, F.,Sun, X.,Tang, W.,Wang, J. (deposition date: 2023-04-14, release date: 2024-01-24, Last modification date: 2024-10-30)
Primary citation	Li, F.,Tai, L.,Sun, X.,Lv, Z.,Tang, W.,Wang, T.,Zhao, Z.,Gong, D.,Ma, S.,Tang, S.,Gu, Q.,Zhu, X.,Yu, M.,Liu, X.,Wang, J. Molecular recognition and activation mechanism of short-chain fatty acid receptors FFAR2/3. Cell Res., 34:323-326, 2024 Cited by PubMed: 38191689 DOI: 10.1038/s41422-023-00914-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation