2W40
| Crystal structure of Plasmodium falciparum glycerol kinase with bound glycerol | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, GLYCEROL KINASE, ... | 著者 | Schnick, C, Polley, S.D, Fivelman, Q.L, Ranford-Cartwright, L, Wilkinson, S.R, Brannigan, J.A, Wilkinson, A.J, Baker, D.A. | 登録日 | 2008-11-18 | 公開日 | 2008-12-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Structure and Non-Essential Function of Glycerol Kinase in Plasmodium Falciparum Blood Stages. Mol.Microbiol., 71, 2009
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2W41
| Crystal structure of Plasmodium falciparum glycerol kinase with ADP | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL KINASE, ... | 著者 | Schnick, C, Polley, S.D, Fivelman, Q.L, Ranford-Cartwright, L, Wilkinson, S.R, Brannigan, J.A, Wilkinson, A.J, Baker, D.A. | 登録日 | 2008-11-18 | 公開日 | 2008-12-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Structure and Non-Essential Function of Glycerol Kinase in Plasmodium Falciparum Blood Stages. Mol.Microbiol., 71, 2009
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7SXQ
| Plasmodium falciparum apicoplast DNA polymerase (exo-minus) without affinity tag | 分子名称: | 1,2-ETHANEDIOL, Apicoplast DNA polymerase, CHLORIDE ION, ... | 著者 | Nieto, N, Chheda, P, Kerns, R, Nelson, S, Honzatko, R. | 登録日 | 2021-11-24 | 公開日 | 2022-10-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Promising antimalarials targeting apicoplast DNA polymerase from Plasmodium falciparum. Eur.J.Med.Chem., 243, 2022
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7SXL
| Plasmodium falciparum apicoplast DNA polymerase (exo-minus) without affinity tag | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Nieto, N, Chheda, P, Kerns, R, Nelson, S, Honzatko, R. | 登録日 | 2021-11-23 | 公開日 | 2022-10-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Promising antimalarials targeting apicoplast DNA polymerase from Plasmodium falciparum. Eur.J.Med.Chem., 243, 2022
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4E4R
| EutD phosphotransacetylase from Staphylococcus aureus | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | 著者 | Osipiuk, J, Zhou, M, Peterson, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2012-03-13 | 公開日 | 2012-03-28 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | EutD phosphotransacetylase from Staphylococcus aureus. To be Published
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4A5P
| Structure of the Shigella flexneri MxiA protein | 分子名称: | 1,2-ETHANEDIOL, PROTEIN MXIA | 著者 | Abrusci, P, Vegara-Irigaray, M, Johnson, S, Roversi, P, Friede, M.E, Deane, J.E, Tang, C.M, Lea, S.M. | 登録日 | 2011-10-26 | 公開日 | 2012-11-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Architecture of the major component of the type III secretion system export apparatus. Nat.Struct.Mol.Biol., 20, 2013
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6P7W
| Structure of the K. lactis CBF3 core - Ndc10 D1 complex | 分子名称: | Cep3, Ctf13, Ndc10, ... | 著者 | Lee, P.D, Wei, H, Tan, D, Harrison, S.C. | 登録日 | 2019-06-06 | 公開日 | 2019-09-18 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structure of the Centromere Binding Factor 3 Complex from Kluyveromyces lactis. J.Mol.Biol., 431, 2019
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8UCS
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6P7V
| Structure of the K. lactis CBF3 core | 分子名称: | Cep3, Ctf13, Skp1 | 著者 | Lee, P.D, Wei, H, Tan, D, Harrison, S.C. | 登録日 | 2019-06-06 | 公開日 | 2019-09-11 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structure of the Centromere Binding Factor 3 Complex from Kluyveromyces lactis. J.Mol.Biol., 431, 2019
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3IHS
| Crystal Structure of a Phosphocarrier Protein HPr from Bacillus anthracis str. Ames | 分子名称: | Phosphocarrier protein HPr | 著者 | Brunzelle, J.S, Anderson, S.M, Skarina, T, Onopriyenko, O, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2009-07-30 | 公開日 | 2009-08-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Crystal Structure of a Phosphocarrier Protein HPr from Bacillus anthracis str. Ames To be Published
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4BQU
| Japanin from Rhipicephalus appendiculatus bound to cholesterol: Orthorhombic crystal form | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Roversi, P, Johnson, S, Preston, S, Austyn, J.M, Nuttall, P, Lea, S.M. | 登録日 | 2013-06-02 | 公開日 | 2014-06-18 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Structural basis of cholesterol binding by a novel clade of dendritic cell modulators from ticks. Sci Rep, 7, 2017
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5CFP
| Crystal structure of anemone STING (Nematostella vectensis) 'humanized' F276K in complex with 3', 3' c-di-GMP, c[G(3', 5')pG(3', 5')p]' | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Stimulator of Interferon Genes | 著者 | Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E. | 登録日 | 2015-07-08 | 公開日 | 2015-08-26 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.066 Å) | 主引用文献 | Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling. Mol.Cell, 59, 2015
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5CFO
| Crystal structure of anemone STING (Nematostella vectensis) in apo 'rotated' open conformation | 分子名称: | Stimulator of Interferon Genes | 著者 | Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E. | 登録日 | 2015-07-08 | 公開日 | 2015-08-26 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | 主引用文献 | Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling. Mol.Cell, 59, 2015
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8FNW
| Structure of RdrA-RdrB complex from Escherichia coli RADAR defense system | 分子名称: | Adenosine deaminase, Archaeal ATPase, ZINC ION | 著者 | Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J. | 登録日 | 2022-12-28 | 公開日 | 2023-02-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (6.73 Å) | 主引用文献 | Cryo-EM structure of the RADAR supramolecular anti-phage defense complex. Cell, 186, 2023
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8FNT
| Structure of RdrA from Escherichia coli RADAR defense system | 分子名称: | Archaeal ATPase | 著者 | Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J. | 登録日 | 2022-12-28 | 公開日 | 2023-02-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.52 Å) | 主引用文献 | Cryo-EM structure of the RADAR supramolecular anti-phage defense complex. Cell, 186, 2023
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8FNV
| Structure of RdrB from Escherichia coli RADAR defense system | 分子名称: | Adenosine deaminase, ZINC ION | 著者 | Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J. | 登録日 | 2022-12-28 | 公開日 | 2023-02-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.11 Å) | 主引用文献 | Cryo-EM structure of the RADAR supramolecular anti-phage defense complex. Cell, 186, 2023
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8FNU
| Structure of RdrA from Streptococcus suis RADAR defense system | 分子名称: | KAP NTPase domain-containing protein | 著者 | Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J. | 登録日 | 2022-12-28 | 公開日 | 2023-02-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Cryo-EM structure of the RADAR supramolecular anti-phage defense complex. Cell, 186, 2023
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5CFL
| Crystal structure of anemone STING (Nematostella vectensis) in complex with 3', 3' c-di-GMP, c[G(3', 5')pG(3', 5')p] | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CITRATE ANION, Stimulator of Interferon Genes | 著者 | Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E. | 登録日 | 2015-07-08 | 公開日 | 2015-08-26 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.836 Å) | 主引用文献 | Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling. Mol.Cell, 59, 2015
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5CFR
| Crystal structure of anemone STING (Nematostella vectensis) in apo 'unrotated' closed conformation | 分子名称: | CALCIUM ION, Stimulator of Interferon Genes | 著者 | Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E. | 登録日 | 2015-07-08 | 公開日 | 2015-08-26 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling. Mol.Cell, 59, 2015
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5BOM
| DNA polymerase beta binary complex with a templating 5ClC | 分子名称: | DNA (5'-D(*CP*CP*GP*AP*CP*(4U3)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | 著者 | Freudenthal, B.D, Wilson, S.H. | 登録日 | 2015-05-27 | 公開日 | 2015-08-19 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.0002 Å) | 主引用文献 | Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer. Proc.Natl.Acad.Sci.USA, 112, 2015
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5CFN
| Crystal structure of anemone STING (Nematostella vectensis) in complex with 3',3' c-di-AMP, c[A(3',5')pA(3',5')p] | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Stimulator of Interferon Genes | 著者 | Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E. | 登録日 | 2015-07-08 | 公開日 | 2015-08-26 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling. Mol.Cell, 59, 2015
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5CFM
| Crystal structure of anemone STING (Nematostella vectensis) in complex with 3', 3' cGAMP, c[G(3', 5')pA(3', 5')p] | 分子名称: | 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, CITRATE ANION, Stimulator of Interferon Genes | 著者 | Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E. | 登録日 | 2015-07-08 | 公開日 | 2015-08-26 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.994 Å) | 主引用文献 | Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling. Mol.Cell, 59, 2015
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4BOE
| Japanin from Rhipicephalus appendiculatus bound to cholesterol: Tetragonal crystal form | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | 著者 | Roversi, P, Johnson, S, Preston, S, Austyn, J.M, Nuttall, P, Lea, S.M. | 登録日 | 2013-05-19 | 公開日 | 2014-05-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Structural basis of cholesterol binding by a novel clade of dendritic cell modulators from ticks. Sci Rep, 7, 2017
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8G2Y
| Cryo-EM structure of ADGRF1 coupled to miniGs/q | 分子名称: | Adhesion G-protein-coupled receptor F1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Jones, D, Rawson, S, Blacklow, S. | 登録日 | 2023-02-06 | 公開日 | 2023-05-10 | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | 主引用文献 | Tethered agonist activated ADGRF1 structure and signalling analysis reveal basis for G protein coupling. Nat Commun, 14, 2023
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6CBP
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