5BOM

DNA polymerase beta binary complex with a templating 5ClC

Summary for 5BOM

DescriptorDNA polymerase beta, DNA (5'-D(P*GP*TP*CP*GP*G)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ... (6 entities in total)
Functional Keywordstransferase, lyase/dna, lyase-dna complex
Biological sourceHomo sapiens (Human)
More
Cellular locationNucleus P06746
Total number of polymer chains4
Total molecular weight47771.26
Authors
Freudenthal, B.D.,Wilson, S.H. (deposition date: 2015-05-27, release date: 2015-08-19, Last modification date: 2017-09-06)
Primary citation
Fedeles, B.I.,Freudenthal, B.D.,Yau, E.,Singh, V.,Chang, S.C.,Li, D.,Delaney, J.C.,Wilson, S.H.,Essigmann, J.M.
Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer.
Proc.Natl.Acad.Sci.USA, 112:E4571-E4580, 2015
PubMed: 26243878 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1507709112
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.0002 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.216300.4%2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution