7CX2
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![BU of 7cx2 by Molmil](/molmil-images/mine/7cx2) | Cryo-EM structure of the PGE2-bound EP2-Gs complex | 分子名称: | (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Qu, C, Mao, C, Xiao, P, Shen, Q, Zhong, Y, Yang, F, Shen, D, Tao, X, Zhang, H, Yan, X, Zhao, R, He, J, Guan, Y, Zhang, C, Hou, G, Zhang, P, Yu, X, Guan, Y, Sun, J, Zhang, Y. | 登録日 | 2020-09-01 | 公開日 | 2021-05-05 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E 2 receptor EP2 subtype. Sci Adv, 7, 2021
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6PB0
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![BU of 6pb0 by Molmil](/molmil-images/mine/6pb0) | Cryo-EM structure of Urocortin 1-bound Corticotropin-releasing factor 1 receptor in complex with Gs protein and Nb35 | 分子名称: | CHOLESTEROL, Corticotropin-releasing factor receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Ma, S, Shen, Q, Zhao, L.-H, Mao, C, Zhou, X.E, Shen, D.-D, de Waal, P.W, Bi, P, Li, C, Jiang, Y, Wang, M.-W, Sexton, P.M, Wootten, D, Melcher, K, Zhang, Y, Xu, H.E. | 登録日 | 2019-06-12 | 公開日 | 2020-02-12 | 最終更新日 | 2020-02-19 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors. Mol.Cell, 77, 2020
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7BV1
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![BU of 7bv1 by Molmil](/molmil-images/mine/7bv1) | Cryo-EM structure of the apo nsp12-nsp7-nsp8 complex | 分子名称: | Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase, ... | 著者 | Yin, W, Mao, C, Luan, X, Shen, D, Shen, Q, Su, H, Wang, X, Zhou, F, Zhao, W, Gao, M, Chang, S, Xie, Y.C, Tian, G, Jiang, H.W, Tao, S.C, Shen, J, Jiang, Y, Jiang, H, Xu, Y, Zhang, S, Zhang, Y, Xu, H.E. | 登録日 | 2020-04-09 | 公開日 | 2020-04-22 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. Science, 368, 2020
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7BV2
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![BU of 7bv2 by Molmil](/molmil-images/mine/7bv2) | The nsp12-nsp7-nsp8 complex bound to the template-primer RNA and triphosphate form of Remdesivir(RTP) | 分子名称: | MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ... | 著者 | Yin, W, Mao, C, Luan, X, Shen, D, Shen, Q, Su, H, Wang, X, Zhou, F, Zhao, W, Gao, M, Chang, S, Xie, Y.C, Tian, G, Jiang, H.W, Tao, S.C, Shen, J, Jiang, Y, Jiang, H, Xu, Y, Zhang, S, Zhang, Y, Xu, H.E. | 登録日 | 2020-04-09 | 公開日 | 2020-04-22 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. Science, 368, 2020
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7C7Q
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![BU of 7c7q by Molmil](/molmil-images/mine/7c7q) | Cryo-EM structure of the baclofen/BHFF-bound human GABA(B) receptor in active state | 分子名称: | (3S)-5,7-ditert-butyl-3-oxidanyl-3-(trifluoromethyl)-1-benzofuran-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ... | 著者 | Mao, C, Shen, C, Li, C, Shen, D, Xu, C, Zhang, S, Zhou, R, Shen, Q, Chen, L, Jiang, Z, Liu, J, Zhang, Y. | 登録日 | 2020-05-26 | 公開日 | 2020-07-01 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Cryo-EM structures of inactive and active GABABreceptor. Cell Res., 30, 2020
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7C7S
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![BU of 7c7s by Molmil](/molmil-images/mine/7c7s) | Cryo-EM structure of the CGP54626-bound human GABA(B) receptor in inactive state. | 分子名称: | (R)-(cyclohexylmethyl)[(2S)-3-{[(1S)-1-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropyl]phosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ... | 著者 | Mao, C, Shen, C, Li, C, Shen, D, Xu, C, Zhang, S, Zhou, R, Shen, Q, Chen, L, Jiang, Z, Liu, J, Zhang, Y. | 登録日 | 2020-05-26 | 公開日 | 2020-07-01 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM structures of inactive and active GABABreceptor. Cell Res., 30, 2020
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6PB1
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![BU of 6pb1 by Molmil](/molmil-images/mine/6pb1) | Cryo-EM structure of Urocortin 1-bound Corticotropin-releasing factor 2 receptor in complex with Gs protein and Nb35 | 分子名称: | CHOLESTEROL, Corticotropin-releasing factor receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Ma, S, Shen, Q, Zhao, L.-H, Mao, C, Zhou, X.E, Shen, D.-D, de Waal, P.W, Bi, P, Li, C, Jiang, Y, Wang, M.-W, Sexton, P.M, Wootten, D, Melcher, K, Zhang, Y, Xu, H.E. | 登録日 | 2019-06-12 | 公開日 | 2020-02-12 | 最終更新日 | 2020-02-19 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors. Mol.Cell, 77, 2020
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7WIG
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![BU of 7wig by Molmil](/molmil-images/mine/7wig) | Cryo-EM structure of the L-054,264-bound human SSTR2-Gi1 complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Chen, L, Wang, W, Dong, Y, Shen, D, Guo, J, Qin, J, Zhang, H, Shen, Q, Zhang, Y, Mao, C. | 登録日 | 2022-01-03 | 公開日 | 2022-06-01 | 最終更新日 | 2022-08-17 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structures of the endogenous peptide- and selective non-peptide agonist-bound SSTR2 signaling complexes. Cell Res., 32, 2022
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7WIC
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![BU of 7wic by Molmil](/molmil-images/mine/7wic) | Cryo-EM structure of the SS-14-bound human SSTR2-Gi1 complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Chen, L, Wang, W, Dong, Y, Shen, D, Guo, J, Qin, J, Zhang, H, Shen, Q, Zhang, Y, Mao, C. | 登録日 | 2022-01-03 | 公開日 | 2022-06-01 | 最終更新日 | 2022-08-17 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structures of the endogenous peptide- and selective non-peptide agonist-bound SSTR2 signaling complexes. Cell Res., 32, 2022
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8YXR
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8YXM
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8WU1
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![BU of 8wu1 by Molmil](/molmil-images/mine/8wu1) | Cryo-EM structure of CB1-beta-arrestin1 complex | 分子名称: | Beta-arrestin-1, Cannabinoid receptor 1,Vasopressin V2 receptor, Fab30 heavy chain, ... | 著者 | Liao, Y, Zhang, H, Shen, Q, Cai, C. | 登録日 | 2023-10-19 | 公開日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structure of CB1-beta-arrestin1 complex to be published
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8X01
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8YXL
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![BU of 8yxl by Molmil](/molmil-images/mine/8yxl) | |
8YXO
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8YXP
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7XW9
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![BU of 7xw9 by Molmil](/molmil-images/mine/7xw9) | Cryo-EM structure of the TRH-bound human TRHR-Gq complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... | 著者 | Ji, S, Dong, Y, Chen, L, Zang, S, Shen, D, Guo, J, Qin, J, Zhang, H, Wang, W, Shen, Q, Mao, C, Zhang, Y. | 登録日 | 2022-05-26 | 公開日 | 2022-12-28 | 最終更新日 | 2024-01-10 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Molecular basis for the activation of thyrotropin-releasing hormone receptor. Cell Discov, 8, 2022
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7XA3
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![BU of 7xa3 by Molmil](/molmil-images/mine/7xa3) | Cryo-EM structure of the CCL2 bound CCR2-Gi complex | 分子名称: | C-C motif chemokine 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Shao, Z, Tan, Y, Shen, Q, Yao, B, Hou, L, Qin, J, Xu, P, Mao, C, Chen, L, Zhang, H, Shen, D, Zhang, C, Li, W, Du, X, Li, F, Chen, Z, Jiang, Y, Xu, H.E, Ying, S, Ma, H, Zhang, Y, Shen, H. | 登録日 | 2022-03-17 | 公開日 | 2022-08-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Molecular insights into ligand recognition and activation of chemokine receptors CCR2 and CCR3. Cell Discov, 8, 2022
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7X9Y
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![BU of 7x9y by Molmil](/molmil-images/mine/7x9y) | Cryo-EM structure of the apo CCR3-Gi complex | 分子名称: | C-C chemokine receptor type 3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Shao, Z, Tan, Y, Shen, Q, Yao, B, Hou, L, Qin, J, Xu, P, Mao, C, Chen, L, Zhang, H, Shen, D, Zhang, C, Li, W, Du, X, Li, F, Chen, Z, Jiang, Y, Xu, H.E, Ying, S, Ma, H, Zhang, Y, Shen, H. | 登録日 | 2022-03-16 | 公開日 | 2022-08-24 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Molecular insights into ligand recognition and activation of chemokine receptors CCR2 and CCR3. Cell Discov, 8, 2022
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7VL8
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![BU of 7vl8 by Molmil](/molmil-images/mine/7vl8) | Cryo-EM structure of the Apo CCR1-Gi complex | 分子名称: | C-C chemokine receptor type 1, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Shao, Z, Shen, Q, Mao, C, Yao, B, Chen, L, Zhang, H, Shen, D, Zhang, C, Li, W, Du, X, Li, F, Ma, H, Chen, Z, Xu, H.E, Ying, S, Zhang, Y, Shen, H. | 登録日 | 2021-10-02 | 公開日 | 2022-03-23 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1. Nat.Chem.Biol., 18, 2022
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7VLA
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![BU of 7vla by Molmil](/molmil-images/mine/7vla) | Cryo-EM structure of the CCL15(27-92) bound CCR1-Gi complex | 分子名称: | C-C chemokine receptor type 1, CCL15(27-92), CHOLESTEROL, ... | 著者 | Shao, Z, Shen, Q, Mao, C, Yao, B, Chen, L, Zhang, H, Shen, D, Zhang, C, Li, W, Du, X, Li, F, Ma, H, Chen, Z, Xu, H.E, Ying, S, Zhang, Y, Shen, H. | 登録日 | 2021-10-02 | 公開日 | 2022-03-23 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1. Nat.Chem.Biol., 18, 2022
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7VL9
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![BU of 7vl9 by Molmil](/molmil-images/mine/7vl9) | Cryo-EM structure of the CCL15(26-92) bound CCR1-Gi complex | 分子名称: | C-C chemokine receptor type 1, CCL15(26-92), CHOLESTEROL, ... | 著者 | Shao, Z, Shen, Q, Mao, C, Yao, B, Chen, L, Zhang, H, Shen, D, Zhang, C, Li, W, Du, X, Li, F, Ma, H, Chen, Z, Xu, H.E, Ying, S, Zhang, Y, Shen, H. | 登録日 | 2021-10-02 | 公開日 | 2022-03-23 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1. Nat.Chem.Biol., 18, 2022
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8IKJ
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![BU of 8ikj by Molmil](/molmil-images/mine/8ikj) | Cryo-EM structure of the inactive CD97 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Adhesion G protein-coupled receptor E5,Soluble cytochrome b562,Adhesion G protein-coupled receptor E5 subunit beta | 著者 | Mao, C, Zhao, R, Dong, Y, Gao, M, Chen, L, Zhang, C, Xiao, P, Guo, J, Qin, J, Shen, D, Ji, S, Zang, S, Zhang, H, Wang, W, Shen, Q, Sun, P, Zhang, Y. | 登録日 | 2023-02-28 | 公開日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Conformational transitions and activation of the adhesion receptor CD97. Mol.Cell, 84, 2024
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5XDM
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6JC3
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![BU of 6jc3 by Molmil](/molmil-images/mine/6jc3) | The Cryo-EM structure of nucleoprotein-RNA complex of Newcastle disease virus | 分子名称: | Nucleocapsid, polyU | 著者 | Song, X, Shan, H, Zhu, Y, Ding, W, Ouyang, S, Shen, Q.T, Liu, Z.J. | 登録日 | 2019-01-28 | 公開日 | 2019-08-07 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Self-capping of nucleoprotein filaments protects the Newcastle disease virus genome. Elife, 8, 2019
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