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PDB: 412 件

8K5C
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Cryo-EM structure of Acipimox bound human hydroxy-carboxylic acid receptor 2 (Local refinement)
分子名称: 5-methyl-4-oxidanyl-pyrazin-4-ium-2-carboxylic acid, Human hydroxycarboxylic acid receptor 2
著者Park, J.H, Ishimoto, N, Park, S.Y.
登録日2023-07-21
公開日2023-11-22
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
8K5B
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BU of 8k5b by Molmil
Cryo-EM structure of niacin bound human hydroxy-carboxylic acid receptor 2 (Local refinement)
分子名称: Human Hydroxycarboxylic acid receptor 2, NICOTINIC ACID
著者Park, J.H, Ishimoto, N, Park, S.Y.
登録日2023-07-21
公開日2023-11-22
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
8K5D
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BU of 8k5d by Molmil
Cryo-EM structure of GSK256073 bound human hydroxy-carboxylic acid receptor 2 (Local refinement)
分子名称: 8-chloranyl-3-pentyl-7H-purine-2,6-dione, Human hydroxycarboxylic acid receptor 2
著者Park, J.H, Ishimoto, N, Park, S.Y.
登録日2023-07-21
公開日2023-11-22
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
6LE5
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Crystal structure of the mitochondrial calcium uptake 1 and 2 heterodimer (MICU1-MICU2 heterodimer) in an apo state
分子名称: Calcium uptake protein 1, mitochondrial, Calcium uptake protein 2
著者Park, J, Lee, Y, Park, T, Kang, J.Y, Jin, M, Yang, J, Eom, S.H.
登録日2019-11-24
公開日2020-03-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of the MICU1-MICU2 heterodimer provides insights into the gatekeeping threshold shift.
Iucrj, 7, 2020
6LTY
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DNA bound antitoxin HigA3
分子名称: DNA (5'-D(P*CP*CP*AP*CP*GP*AP*GP*AP*TP*AP*TP*AP*AP*CP*CP*TP*AP*GP*AP*G)-3'), DNA (5'-D(P*CP*TP*CP*TP*AP*GP*GP*TP*TP*AP*TP*AP*TP*CP*TP*CP*GP*TP*GP*G)-3'), Putative antitoxin HigA3
著者Park, J.Y, Lee, B.J.
登録日2020-01-23
公開日2020-07-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.28 Å)
主引用文献Induced DNA bending by unique dimerization of HigA antitoxin.
Iucrj, 7, 2020
6LTZ
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Induced DNA bending by unique dimerization of HigA antitoxin
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Park, J.Y, Lee, B.J.
登録日2020-01-23
公開日2020-07-15
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.973 Å)
主引用文献Induced DNA bending by unique dimerization of HigA antitoxin.
Iucrj, 7, 2020
4ZYA
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BU of 4zya by Molmil
The N-terminal extension domain of human asparaginyl-tRNA synthetase
分子名称: Asparagine--tRNA ligase, cytoplasmic, CHLORIDE ION, ...
著者Park, J.S, Park, M.C, Goughnour, P, Kim, H.S, Kim, S.J, Kim, H.J, Kim, S.H, Han, B.W.
登録日2015-05-21
公開日2016-05-25
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Unique N-terminal extension domain of human asparaginyl-tRNA synthetase elicits CCR3-mediated chemokine activity.
Int. J. Biol. Macromol., 120, 2018
6L2U
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Soluble methane monooxygenase reductase FAD-binding domain from Methylosinus sporium.
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Methane monooxygenase
著者Park, J.H, Ha, S.C, Rao, Z, Yoo, H, Yoon, C, Kim, S.Y, Kim, D.S, Lee, S.J.
登録日2019-10-07
公開日2021-03-03
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Elucidation of the electron transfer environment in the MMOR FAD-binding domain from Methylosinus sporium 5.
Dalton Trans, 50, 2021
8DTL
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Cryo-EM structure of insulin receptor (IR) bound with S597 peptide
分子名称: Insulin mimetic peptide S597, Insulin receptor
著者Park, J, Li, J, Mayer, J.P, Ball, K.A, Wu, J.Y, Hall, C, Accili, D, Stowell, M.H.B, Bai, X.C, Choi, E.
登録日2022-07-25
公開日2022-09-07
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Activation of the insulin receptor by an insulin mimetic peptide.
Nat Commun, 13, 2022
8DTM
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Cryo-EM structure of insulin receptor (IR) bound with S597 component 2
分子名称: Insulin mimetic peptide S597 component 2, Insulin receptor
著者Park, J, Li, J, Mayer, J.P, Ball, K.A, Wu, J.Y, Hall, C, Accili, D, Stowell, M.H.B, Bai, X.C, Choi, E.
登録日2022-07-26
公開日2022-09-07
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Activation of the insulin receptor by an insulin mimetic peptide.
Nat Commun, 13, 2022
8WFP
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BU of 8wfp by Molmil
Crystal structure of polo-like kinase(PLK1)PBD in complex with DD-1
分子名称: DD-1, Serine/threonine-protein kinase PLK1
著者Park, J, La, Y.K, Bang, J.K, Lee, S.J.
登録日2023-09-20
公開日2024-09-25
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Degradation of Polo-like Kinase 1 by the Novel Poly-Arginine N-Degron Pathway PROTAC Regulates Tumor Growth in Nonsmall Cell Lung Cancer.
J.Med.Chem., 67, 2024
9B9V
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BU of 9b9v by Molmil
Cryo-EM structure of the ZBTB9 BTB domain filament
分子名称: Zinc finger and BTB domain-containing protein 9
著者Park, J, Hunkeler, M, Fischer, E.S.
登録日2024-04-03
公開日2024-07-24
実験手法ELECTRON MICROSCOPY (8.1 Å)
主引用文献Polymerization of ZBTB transcription factors regulates chromatin occupancy.
Mol.Cell, 84, 2024
8IS9
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CrtMLIKE with one FsPP molecule
分子名称: CrtM, MAGNESIUM ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE
著者Park, J.Y.
登録日2023-03-20
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献CrtMLIKE with one FsPP molecule
To Be Published
8IS8
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CrtMLIKE with two GsPP molecules
分子名称: CrtM, GERANYL S-THIOLODIPHOSPHATE, MAGNESIUM ION
著者Park, J.y.
登録日2023-03-20
公開日2024-06-26
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献CrtMLIKE with two GsPP molecules
To Be Published
8IS6
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Apo-CrtMLIKE
分子名称: CrtM
著者Park, J.Y.
登録日2023-03-20
公開日2024-06-26
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献CrtMKLIKE Apo structure
To Be Published
8ISA
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BU of 8isa by Molmil
CrtMLIKE with one GsPP molecule
分子名称: CrtM, GERANYL S-THIOLODIPHOSPHATE
著者Park, J.Y.
登録日2023-03-20
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献CrtMLIKE with one GsPP molecule
To Be Published
8IS7
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BU of 8is7 by Molmil
CrtMLIKE with two FsPP molecules.
分子名称: CrtM, MAGNESIUM ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE
著者Park, J.Y.
登録日2023-03-20
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献CrtMLIKE with two FsPP molecules.
To Be Published
4GKF
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BU of 4gkf by Molmil
Crystal structure and characterization of Cmr5 protein from Pyrococcus furiosus
分子名称: CRISPR system Cmr subunit Cmr5
著者Park, J, Sun, J, Park, S, Hwang, H, Park, M, Shin, M.S.
登録日2012-08-11
公開日2013-01-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of Cmr5 from Pyrococcus furiosus and its functional implications
Febs Lett., 587, 2013
9B9R
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BU of 9b9r by Molmil
Cryo-EM structure of the ZBTB5 BTB domain filament
分子名称: Zinc finger and BTB domain-containing protein 5
著者Park, J, Hunkeler, M, Fischer, E.S.
登録日2024-04-03
公開日2024-07-24
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Polymerization of ZBTB transcription factors regulates chromatin occupancy.
Mol.Cell, 84, 2024
8D37
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BU of 8d37 by Molmil
Human mitochondrial DNA polymerase gamma ternary complex with GT basepair in replication conformer
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (25-MER), ...
著者Park, J, Yin, Y.W.
登録日2022-05-31
公開日2023-05-24
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (2.65 Å)
主引用文献Pol gamma coordinates DNA synthesis and proofreading to ensure mitochondrial genome integrity.
Nat.Struct.Mol.Biol., 30, 2023
8D33
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BU of 8d33 by Molmil
Human mitochondrial DNA polymerase gamma ternary complex with GC basepair
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (25-MER), ...
著者Park, J, Yin, Y.W.
登録日2022-05-31
公開日2023-05-24
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.46 Å)
主引用文献Pol gamma coordinates DNA synthesis and proofreading to ensure mitochondrial genome integrity.
Nat.Struct.Mol.Biol., 30, 2023
8D3R
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Human mitochondrial DNA polymerase gamma ternary complex with GT basepair in intermediate conformer
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*TP*AP*T)-3'), ...
著者Park, J, Yin, Y.W.
登録日2022-06-01
公開日2023-05-24
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Pol gamma coordinates DNA synthesis and proofreading to ensure mitochondrial genome integrity.
Nat.Struct.Mol.Biol., 30, 2023
8D42
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Human mitochondrial DNA polymerase gamma ternary complex with GT basepair in editing conformer (composite)
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*TP*AP*T)-3'), ...
著者Park, J, Yin, Y.W.
登録日2022-06-01
公開日2023-05-24
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献Pol gamma coordinates DNA synthesis and proofreading to ensure mitochondrial genome integrity.
Nat.Struct.Mol.Biol., 30, 2023
8H2G
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Cryo-EM structure of niacin bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Park, J.H, Ishimoto, N, Park, S.Y.
登録日2022-10-06
公開日2023-10-11
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2
Nat Commun, 14, 2023
8I7W
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Cryo-EM structure of GSK256073 bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer
分子名称: 8-chloranyl-3-pentyl-7H-purine-2,6-dione, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Park, J.H, Ishimoto, N, Park, S.Y.
登録日2023-02-02
公開日2024-02-07
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.39 Å)
主引用文献Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023

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件を2024-10-30に公開中

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