1JJD
| |
7TI9
| Crystal structure of the ubiquitin-like domain 1 (Ubl1) of Nsp3 from SARS-CoV-2, form 2 | Descriptor: | CHLORIDE ION, GLYCEROL, Papain-like protease nsp3 | Authors: | Stogios, P.J, Skarina, T, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2022-01-13 | Release date: | 2022-01-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Crystal structure of the ubiquitin-like domain 1 (Ubl1) of Nsp3 from SARS-CoV-2, form 2 To Be Published
|
|
5UXB
| Crystal structure of macrolide 2'-phosphotransferase MphH from Brachybacterium faecium, apoenzyme | Descriptor: | CHLORIDE ION, Macrolide 2'-phosphotransferase MphH | Authors: | Stogios, P.J, Skarina, T, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2017-02-22 | Release date: | 2017-07-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.794 Å) | Cite: | The evolution of substrate discrimination in macrolide antibiotic resistance enzymes. Nat Commun, 9, 2018
|
|
5VIG
| Crystal structure of anti-Zika antibody Z006 bound to Zika virus envelope protein DIII | Descriptor: | CITRATE ANION, Fab heavy chain, Fab light chain, ... | Authors: | Keeffe, J.R, West Jr, A.P, Gristick, H.B, Bjorkman, P.J. | Deposit date: | 2017-04-16 | Release date: | 2017-05-03 | Last modified: | 2017-05-17 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico. Cell, 169, 2017
|
|
5NPZ
| Porcine (Sus scrofa) Major Histocompatibility Complex, class I, presenting EFEDLTFLA | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | Authors: | Rizkallah, P.J, Tungatt, K, Sewell, A.K. | Deposit date: | 2017-04-19 | Release date: | 2018-05-02 | Last modified: | 2019-05-15 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig. Plos Pathog., 14, 2018
|
|
5VKW
| Crystal structure of adenylosuccinate lyase ADE13 from Candida albicans | Descriptor: | Adenylosuccinate lyase, CALCIUM ION, CHLORIDE ION, ... | Authors: | Stogios, P.J, Evdokimova, E, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2017-04-24 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.998 Å) | Cite: | Crystal structure of adenylosuccinate lyase ADE13 from Candida albicans To Be Published
|
|
6BY4
| Single-State 14-mer UUCG Tetraloop calculated from Exact NOEs | Descriptor: | RNA (5'-R(P*GP*GP*CP*AP*CP*UP*UP*CP*GP*GP*UP*GP*CP*C)-3') | Authors: | Nichols, P.J, Henen, M.A, Born, A, Strotz, D, Guntert, P, Vogeli, B. | Deposit date: | 2017-12-19 | Release date: | 2018-06-13 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | High-resolution small RNA structures from exact nuclear Overhauser enhancement measurements without additional restraints. Commun Biol, 1, 2018
|
|
6BL9
| |
6BY5
| Two-State 14-mer UUCG Tetraloop calculated from Exact NOEs (State one: Conformers 1-5, State Two: Conformers 6-10) | Descriptor: | RNA (5'-R(P*GP*GP*CP*AP*CP*UP*UP*CP*GP*GP*UP*GP*CP*C)-3') | Authors: | Nichols, P.J, Henen, M.A, Born, A, Strotz, D, Guntert, P, Vogeli, B. | Deposit date: | 2017-12-19 | Release date: | 2018-06-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | High-resolution small RNA structures from exact nuclear Overhauser enhancement measurements without additional restraints. Commun Biol, 1, 2018
|
|
6BQI
| Structure of two-domain translational regulator Yih1 reveals a possible mechanism of action | Descriptor: | Protein IMPACT homolog | Authors: | Harjes, E, Jameson, G.B, Edwards, P.J.B, Goroncy, A.K, Loo, T, Norris, G.E. | Deposit date: | 2017-11-27 | Release date: | 2018-11-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR, SOLUTION SCATTERING | Cite: | Experimentally based structural model of Yih1 provides insight into its function in controlling the key translational regulator Gcn2. Febs Lett., 2020
|
|
5W1Y
| SETD8 in complex with a covalent inhibitor | Descriptor: | 2-(4-methylpiperazin-1-yl)-3-(phenylsulfanyl)naphthalene-1,4-dione, N-lysine methyltransferase KMT5A, UNKNOWN ATOM OR ION | Authors: | Tempel, W, Yu, W, Li, Y, Blum, G, Luo, M, Pittella-Silva, F, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC) | Deposit date: | 2017-06-05 | Release date: | 2017-06-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | SETD8 in complex with a covalent inhibitor to be published
|
|
1JKV
| Crystal Structure of Manganese Catalase from Lactobacillus plantarum complexed with azide | Descriptor: | 1,2-ETHANEDIOL, AZIDE ION, CALCIUM ION, ... | Authors: | Barynin, V.V, Whittaker, M.M, Antonyuk, S.V, Lamzin, V.S, Harrison, P.M, Artymiuk, P.J, Whittaker, J.W. | Deposit date: | 2001-07-13 | Release date: | 2002-07-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Crystal structure of manganese catalase from Lactobacillus plantarum. Structure, 9, 2001
|
|
5NI3
| sfGFP 204-204 mutant dimer | Descriptor: | CHLORIDE ION, GLYCEROL, Green fluorescent protein, ... | Authors: | Worthy, H.L, Rizkallah, P.J. | Deposit date: | 2017-03-23 | Release date: | 2018-09-12 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Association of Fluorescent Protein Pairs and Its Significant Impact on Fluorescence and Energy Transfer Adv Sci, 2020
|
|
6CD7
| Crystal structure of APH(2")-IVa in complex with plazomicin | Descriptor: | (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-4-{[(2S,3R)-3-amino-6-{[(2-hydroxyethyl)amino]methyl}-3,4-dihydro-2H-pyran-2-y l]oxy}-2-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide, APH(2'')-Id, CHLORIDE ION | Authors: | Stogios, P.J, Evdokimova, E, Dong, A, Di Leo, R, Savchenko, A, Satchell, K.J, Joachimiak, J, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2018-02-08 | Release date: | 2018-02-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes. ACS Infect Dis, 4, 2018
|
|
6CG4
| |
1TN7
| Protein Farnesyltransferase Complexed with a TC21 Peptide Substrate and a FPP Analog at 2.3A Resolution | Descriptor: | ACETIC ACID, Fusion protein, Protein farnesyltransferase alpha subunit, ... | Authors: | Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S. | Deposit date: | 2004-06-11 | Release date: | 2004-11-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity. J.Mol.Biol., 343, 2004
|
|
1TNU
| Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a GCINCCKVL Peptide Derived from RhoB | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE, CHLORIDE ION, ... | Authors: | Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S. | Deposit date: | 2004-06-11 | Release date: | 2004-11-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity. J.Mol.Biol., 343, 2004
|
|
1TN6
| Protein Farnesyltransferase Complexed with a Rap2a Peptide Substrate and a FPP Analog at 1.8A Resolution | Descriptor: | ACETIC ACID, Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ... | Authors: | Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S. | Deposit date: | 2004-06-11 | Release date: | 2004-11-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity J.Mol.Biol., 343, 2004
|
|
6CH7
| |
7TPG
| Single-Particle Cryo-EM Structure of the WaaL O-antigen ligase in its ligand bound state | Descriptor: | Fab Heavy (H) Chain, Fab Light (L) Chain, GERANYL DIPHOSPHATE, ... | Authors: | Ashraf, K.U, Nygaard, R, Vickery, O.N, Erramilli, S.K, Herrera, C.M, McConville, T.H, Petrou, V.I, Giacometti, S.I, Dufrisne, M.B, Nosol, K, Zinkle, A.P, Graham, C.L.B, Loukeris, M, Kloss, B, Skorupinska-Tudek, K, Swiezewska, E, Roper, D, Clarke, O.B, Uhlemann, A.C, Kossiakoff, A.A, Trent, M.S, Stansfeld, P.J, Mancia, F. | Deposit date: | 2022-01-25 | Release date: | 2022-04-06 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Structural basis of lipopolysaccharide maturation by the O-antigen ligase. Nature, 604, 2022
|
|
5NMD
| 868 TCR Specific for HLA A02 presenting HIV Epitope SLYNTVATL | Descriptor: | 1,2-ETHANEDIOL, Human T-cell Receptor, beta chain, ... | Authors: | Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K. | Deposit date: | 2017-04-05 | Release date: | 2017-11-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope. Front Immunol, 8, 2017
|
|
6CHK
| Crystal structure of LacI family transcriptional regulator from Lactobacillus casei, Target EFI-512911, with bound TRIS | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, SODIUM ION, ... | Authors: | Patskovsky, Y, Toro, R, Shabalin, I.G, Kowiel, M, Porebski, P.J, Minor, W, Jaskolski, M, Bhosle, R, Al Obaidi, N, Chamala, S, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Lafleur, J, Siedel, R.D, Hillerich, B, Love, J, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative, E.F.I. | Deposit date: | 2018-02-22 | Release date: | 2018-03-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Automatic recognition of ligands in electron density by machine learning. Bioinformatics, 35, 2019
|
|
1TNB
| Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a substrate KKSKTKCVIF Peptide Derived from TC21 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE, CHLORIDE ION, ... | Authors: | Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S. | Deposit date: | 2004-06-11 | Release date: | 2004-11-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity. J.Mol.Biol., 343, 2004
|
|
7TOK
| Crystal structure of the CBM domain of carbohydrate esterase FjoAcXE | Descriptor: | Acetylxylan esterase I | Authors: | Stogios, P.J, Skarina, T, Di Leo, R, Jurak, E, Master, E. | Deposit date: | 2022-01-24 | Release date: | 2022-04-13 | Last modified: | 2022-11-02 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Elucidating Sequence and Structural Determinants of Carbohydrate Esterases for Complete Deacetylation of Substituted Xylans. Molecules, 27, 2022
|
|
7TPJ
| Single-Particle Cryo-EM Structure of the WaaL O-antigen ligase in its apo state | Descriptor: | Fab Heavy (H) Chain, Fab Light (L) Chain, Putative cell surface polysaccharide polymerase/ligase | Authors: | Ashraf, K.U, Nygaard, R, Vickery, O.N, Erramilli, S.K, Herrera, C.M, McConville, T.H, Petrou, V.I, Giacometti, S.I, Dufrisne, M.B, Nosol, K, Zinkle, A.P, Graham, C.L.B, Loukeris, M, Kloss, B, Skorupinska-Tudek, K, Swiezewska, E, Roper, D, Clarke, O.B, Uhlemann, A.C, Kossiakoff, A.A, Trent, M.S, Stansfeld, P.J, Mancia, F. | Deposit date: | 2022-01-25 | Release date: | 2022-04-06 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Structural basis of lipopolysaccharide maturation by the O-antigen ligase. Nature, 604, 2022
|
|