5W1Y
SETD8 in complex with a covalent inhibitor
Summary for 5W1Y
Entry DOI | 10.2210/pdb5w1y/pdb |
Descriptor | N-lysine methyltransferase KMT5A, 2-(4-methylpiperazin-1-yl)-3-(phenylsulfanyl)naphthalene-1,4-dione, UNKNOWN ATOM OR ION, ... (4 entities in total) |
Functional Keywords | structural genomics, structural genomics consortium, sgc, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus: Q9NQR1 |
Total number of polymer chains | 2 |
Total formula weight | 38277.30 |
Authors | Tempel, W.,Yu, W.,Li, Y.,Blum, G.,Luo, M.,Pittella-Silva, F.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Brown, P.J.,Structural Genomics Consortium (SGC) (deposition date: 2017-06-05, release date: 2017-06-21, Last modification date: 2023-10-04) |
Primary citation | Tempel, W.,Yu, W.,Li, Y.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Brown, P.J.,Structural Genomics Consortium (SGC) SETD8 in complex with a covalent inhibitor to be published, |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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