1TN6

Protein Farnesyltransferase Complexed with a Rap2a Peptide Substrate and a FPP Analog at 1.8A Resolution

Summary for 1TN6

Entry DOI	10.2210/pdb1tn6/pdb
Related	1D8D 1FPP 1FT1 1N4Q 1QBQ 1TN7 1TN8 1TNB 1TNO 1TNU 1TNY 1TNZ
Related PRD ID	PRD_900003
Descriptor	Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, peptide derived from the C-terminus of Rap2a, ... (8 entities in total)
Functional Keywords	ftase, farnesyltransferase, farnesyl transferase, prenyltransferase, caax, ras, lipid modification, prenylation, substrate selectivity, transferase
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	95708.63
Authors	Reid, T.S.,Terry, K.L.,Casey, P.J.,Beese, L.S. (deposition date: 2004-06-11, release date: 2004-11-02, Last modification date: 2023-08-23)
Primary citation	Reid, T.S.,Terry, K.L.,Casey, P.J.,Beese, L.S. Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity J.Mol.Biol., 343:417-433, 2004 Cited by PubMed: 15451670 DOI: 10.1016/j.jmb.2004.08.056 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation