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6CG4

Covalently crosslinked trimer of a macrocyclic peptide derived from Abeta(17-36) - (ORN)LCVFFCED(ORN)AII(2-nitrobenzylglycine)L(ORN)V

Summary for 6CG4
Entry DOI10.2210/pdb6cg4/pdb
DescriptorORN-CYS-VAL-PHE-PHE-CYS-GLU-ASP-ORN-ALA-ILE-ILE-EZY-LEU-ORN-VAL, IODIDE ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
Functional Keywordsamyloid, oligomer, alzheimer's disease, abeta, neuropeptide
Biological sourcesynthetic construct
Total number of polymer chains3
Total formula weight7106.03
Authors
Salveson, P.J.,Nowick, J.S. (deposition date: 2018-02-19, release date: 2018-05-16, Last modification date: 2020-01-01)
Primary citationSalveson, P.J.,Haerianardakani, S.,Thuy-Boun, A.,Kreutzer, A.G.,Nowick, J.S.
Controlling the Oligomerization State of A beta-Derived Peptides with Light.
J. Am. Chem. Soc., 140:5842-5852, 2018
Cited by
PubMed: 29627987
DOI: 10.1021/jacs.8b02658
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.083 Å)
Structure validation

217705

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