1TNB

Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a substrate KKSKTKCVIF Peptide Derived from TC21

Summary for 1TNB

Entry DOI	10.2210/pdb1tnb/pdb
Related	1D8D 1N4P 1N4Q 1QBQ 1TN6 1TN7 1TN8 1TNO 1TNU 1TNY 1TNZ
Descriptor	geranylgeranyltransferase type I alpha subunit, Geranylgeranyl transferase type I beta subunit, Fusion protein, ... (8 entities in total)
Functional Keywords	ggtase-i, geranylgeranyltransferase type-i, geranylgeranyl transferase, prenyltransferase, caax, tc21, lipid modification, prenylation, substrate selectivity, transferase
Biological source	Rattus norvegicus (Norway rat) More
Total number of polymer chains	18
Total formula weight	529913.78
Authors	Reid, T.S.,Terry, K.L.,Casey, P.J.,Beese, L.S. (deposition date: 2004-06-11, release date: 2004-11-02, Last modification date: 2023-08-23)
Primary citation	Reid, T.S.,Terry, K.L.,Casey, P.J.,Beese, L.S. Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity. J.Mol.Biol., 343:417-433, 2004 Cited by PubMed: 15451670 DOI: 10.1016/j.jmb.2004.08.056 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.85 Å)

Structure validation