7B4Q
 
 | | Structure of a cold active HSL family esterase reveals mechanisms of low temperature adaptation and substrate specificity | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Rizkallah, P.J, Jones, D.D, Noby, N, Auhim, H. | | Deposit date: | 2020-12-02 | | Release date: | 2021-12-15 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Structure and in silico simulations of a cold-active esterase reveals its prime cold-adaptation mechanism.
Open Biology, 11, 2021
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4WDI
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3DZW
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8OFQ
 | | Human adenovirus type 25 fiber-knob protein | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Fiber, ... | | Authors: | Rizkallah, P.J, Parker, A.L, Mundy, R.M, Baker, A.T. | | Deposit date: | 2023-03-16 | | Release date: | 2023-09-20 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Broad sialic acid usage amongst species D human adenovirus
npj Viruses, 1, 2023
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8OFR
 | | Human adenovirus type 25 fiber-knob protein complexed with sialic acid | | Descriptor: | Fiber, N-acetyl-beta-neuraminic acid | | Authors: | Rizkallah, P.J, Parker, A.L, Mundy, R.M, Baker, A.T. | | Deposit date: | 2023-03-16 | | Release date: | 2023-09-20 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Broad sialic acid usage amongst species D human adenovirus
npj Viruses, 1, 2023
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8OFT
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8OFV
 | | Human adenovirus type 53 fiber-knob protein complexed with sialic acid | | Descriptor: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Rizkallah, P.J, Parker, A.L, Mundy, R.M, Baker, A.T. | | Deposit date: | 2023-03-16 | | Release date: | 2023-09-20 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Broad sialic acid usage amongst species D human adenovirus
npj Viruses, 1, 2023
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8OFP
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8OFS
 | | Human adenovirus type 30 fiber-knob protein complexed with sialic acid | | Descriptor: | Fiber, N-acetyl-beta-neuraminic acid | | Authors: | Rizkallah, P.J, Parker, A.L, Mundy, R.M, Baker, A.T. | | Deposit date: | 2023-03-16 | | Release date: | 2023-09-20 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | Broad sialic acid usage amongst species D human adenovirus
npj Viruses, 1, 2023
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8OFU
 | | Human adenovirus type 53 fiber-knob protein | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Fiber protein, ... | | Authors: | Rizkallah, P.J, Parker, A.L, Mundy, R.M, Baker, A.T. | | Deposit date: | 2023-03-16 | | Release date: | 2023-09-20 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Broad sialic acid usage amongst species D human adenovirus
npj Viruses, 1, 2023
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8A9M
 | | Hippeastrum hybrid agglutinin, HHA, complex with beta-mannose | | Descriptor: | Agglutinin, PHOSPHATE ION, beta-D-mannopyranose | | Authors: | Rizkallah, P.J. | | Deposit date: | 2022-06-28 | | Release date: | 2022-10-05 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | X-ray structure solution of amaryllis lectin by molecular replacement with only 4% of the total diffracting matter.
Acta Crystallogr D Biol Crystallogr, 52, 1996
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2F54
 | | Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity | | Descriptor: | Beta-2-microglobulin, Cancer/testis antigen 1B, HLA class I histocompatibility antigen, ... | | Authors: | Rizkallah, P.J, Jakobsen, B.K, Dunn, S.M, Sami, M. | | Deposit date: | 2005-11-25 | | Release date: | 2006-04-25 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.
Protein Sci., 15, 2006
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2F53
 | | Directed Evolution of Human T-cell Receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without apparent cross-reactivity | | Descriptor: | Beta-2-microglobulin, Cancer/testis antigen 1B, GLYCEROL, ... | | Authors: | Rizkallah, P.J, Jakobsen, B.K, Dunn, S.M, Sami, M. | | Deposit date: | 2005-11-25 | | Release date: | 2006-04-25 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.
Protein Sci., 15, 2006
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2HP4
 | | Computational design and crystal structure of an enhanced affinity mutant human CD8-alpha-alpha co-receptor | | Descriptor: | GLYCEROL, SULFATE ION, T-cell surface glycoprotein CD8 alpha chain | | Authors: | Rizkallah, P.J, Cole, D.K, Jakobsen, B.K, Boulter, J.M, Glick, M, Gao, G.F. | | Deposit date: | 2006-07-17 | | Release date: | 2007-02-06 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Computational design and crystal structure of an enhanced affinity mutant human CD8 alphaalpha coreceptor
Proteins, 67, 2007
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2BCK
 | | Crystal Structure of HLA-A*2402 Complexed with a telomerase peptide | | Descriptor: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | | Authors: | Rizkallah, P.J, Jakobsen, B.K, Cole, D.K, Gao, G.F. | | Deposit date: | 2005-10-19 | | Release date: | 2006-01-10 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of HLA-A*2402 complexed with a telomerase peptide.
Eur.J.Immunol., 36, 2006
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7ZUC
 | | Human Major Histocompatibility Complex A2 allele presenting LLLGIGILV | | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, LEU-LEU-LEU-GLY-ILE-GLY-ILE-LEU-VAL, ... | | Authors: | Rizkallah, P.J, Wall, A, Sewell, A.K, Fuller, A. | | Deposit date: | 2022-05-12 | | Release date: | 2023-05-24 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
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7OP2
 | | Chadox1/ Chimpanzee adenovirus Y25 fiber knob protein | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | | Authors: | Rizkallah, P.J, Baker, A.T, Parker, A.L, Teijeira Crespo, A, Lipka-Lloyd, M. | | Deposit date: | 2021-05-28 | | Release date: | 2021-06-23 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome.
Sci Adv, 7, 2021
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4Z78
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4Z77
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4Z76
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6Z9V
 | | Human Class I Major Histocompatibility Complex, A02 allele, presenting IIGWMWIPV | | Descriptor: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ... | | Authors: | Rizkallah, P.J, Man, S, Redman, J.E. | | Deposit date: | 2020-06-04 | | Release date: | 2021-06-30 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells.
J Immunol., 207, 2021
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6Z9W
 | | Human Class I Major Histocompatibility Complex, A02 allele, presenting LLGWVFAQV | | Descriptor: | Beta-2-microglobulin, LEU-LEU-GLY-TRP-VAL-PHE-ALA-GLN-VAL, MHC class I antigen | | Authors: | Rizkallah, P.J, Man, S, Redman, J.E. | | Deposit date: | 2020-06-04 | | Release date: | 2021-06-30 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells.
J Immunol., 207, 2021
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6Z9X
 | | Human Class I Major Histocompatibility Complex, A02 allele, presenting LLS (t-butyl)Y FGTPT | | Descriptor: | Beta-2-microglobulin, LEU-LEU-SER-TUR-PHE-GLY-THR-PRO-THR, MHC class I antigen, ... | | Authors: | Rizkallah, P.J, Man, S, Redman, J.E. | | Deposit date: | 2020-06-04 | | Release date: | 2021-06-30 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells.
J Immunol., 207, 2021
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7PBE
 | | Emergence of immune escape at dominant SARS-CoV-2 killer T-cell epitope | | Descriptor: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, Human T-cell Receptor YLQ36, ... | | Authors: | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | | Deposit date: | 2021-08-02 | | Release date: | 2022-04-27 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope.
Cell, 185, 2022
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3UTQ
 | | Human HLA-A*0201-ALWGPDPAAA | | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | | Authors: | Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M. | | Deposit date: | 2011-11-26 | | Release date: | 2012-01-25 | | Last modified: | 2012-03-07 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
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