108D
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![BU of 108d by Molmil](/molmil-images/mine/108d) | THE SOLUTION STRUCTURE OF A DNA COMPLEX WITH THE FLUORESCENT BIS INTERCALATOR TOTO DETERMINED BY NMR SPECTROSCOPY | Descriptor: | 1,1-(4,4,8,8-TETRAMETHYL-4,8-DIAZAUNDECAMETHYLENE)-BIS-4-3-METHYL-2,3-DIHYDRO-(BENZO-1,3-THIAZOLE)-2-METHYLIDENE)-QUINOLINIUM, DNA (5'-D(*CP*GP*CP*TP*AP*GP*CP*G)-3') | Authors: | Spielmann, H.P, Wemmer, D.E, Jacobsen, J.P. | Deposit date: | 1995-01-31 | Release date: | 1995-06-03 | Last modified: | 2024-03-13 | Method: | SOLUTION NMR | Cite: | Solution structure of a DNA complex with the fluorescent bis-intercalator TOTO determined by NMR spectroscopy. Biochemistry, 34, 1995
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6TZQ
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![BU of 6tzq by Molmil](/molmil-images/mine/6tzq) | A DNA G-quadruplex/i-motif hybrid | Descriptor: | BARIUM ION, DNA (5'-D(*CP*CP*AP*GP*GP*CP*TP*GP*CP*AP*A)-3') | Authors: | Chu, B, Paukstelis, P.J. | Deposit date: | 2019-08-13 | Release date: | 2019-10-16 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | A DNA G-quadruplex/i-motif hybrid. Nucleic Acids Res., 47, 2019
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5ZZC
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![BU of 5zzc by Molmil](/molmil-images/mine/5zzc) | Crystal structure of the complex of Phosphopantetheine adenylyltransferase from Acinetobacter baumannii with Dephospho Coenzyme A at 1.94A resolution | Descriptor: | CHLORIDE ION, DEPHOSPHO COENZYME A, MAGNESIUM ION, ... | Authors: | Gupta, A, Singh, P.K, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2018-05-31 | Release date: | 2018-06-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Crystal structure of the complex of Phosphopantetheine adenylyltransferase from Acinetobacter baumannii with Dephospho Coenzyme A at 1.94 A resolution To Be Published
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1NFV
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![BU of 1nfv by Molmil](/molmil-images/mine/1nfv) | X-ray structure of Desulfovibrio desulfuricans bacterioferritin: the diiron centre in different catalytic states (as-isolated structure) | Descriptor: | 1,3,5,8-TETRAMETHYL-PORPHINE-2,4,6,7-TETRAPROPIONIC ACID FERROUS COMPLEX, 3-HYDROXYPYRUVIC ACID, FE (III) ION, ... | Authors: | Macedo, S, Romao, C.V, Mitchell, E, Matias, P.M, Liu, M.Y, Xavier, A.V, LeGall, J, Teixeira, M, Lindley, P, Carrondo, M.A. | Deposit date: | 2002-12-16 | Release date: | 2003-04-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The nature of the di-iron site in the bacterioferritin from
Desulfovibrio desulfuricans NAT.STRUCT.BIOL., 10, 2003
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8F5V
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![BU of 8f5v by Molmil](/molmil-images/mine/8f5v) | |
2JEJ
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![BU of 2jej by Molmil](/molmil-images/mine/2jej) | The Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus solfataricus DNA Polymerase IV: Steady-state and Pre-steady-state Kinetics and X- Ray Crystallography of Correct and Incorrect Pairing | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*CP*G)-3', 5'-D(*TP*CP*AP*C BZGP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ... | Authors: | Eoff, R.L, Angel, K.C, Kosekov, I.D, Egli, M, Guengerich, F.P. | Deposit date: | 2007-01-17 | Release date: | 2007-03-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus Solfataricus DNA Polymerase Dpo4: Steady-State and Pre-Steady-State Kinetics and X-Ray Crystallography of Correct and Incorrect Pairing. J.Biol.Chem., 282, 2007
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7R58
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![BU of 7r58 by Molmil](/molmil-images/mine/7r58) | Crystal structure of the GPVI-glenzocimab complex | Descriptor: | CHLORIDE ION, Fab heavy chain, Fab light chain, ... | Authors: | Jandrot-Perrus, M, Lebozec, K, Rose, N, Welin, M, Billiald, P. | Deposit date: | 2022-02-10 | Release date: | 2022-11-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.902 Å) | Cite: | Targeting platelet GPVI with glenzocimab: a novel mechanism for inhibition. Blood Adv, 7, 2023
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8F7C
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![BU of 8f7c by Molmil](/molmil-images/mine/8f7c) | Cryo-EM structure of human pannexin 2 | Descriptor: | Pannexin-2, Soluble cytochrome b562 fusion | Authors: | He, Z, Yuan, P. | Deposit date: | 2022-11-18 | Release date: | 2023-04-05 | Method: | ELECTRON MICROSCOPY (3.92 Å) | Cite: | Structural and functional analysis of human pannexin 2 channel. Nat Commun, 14, 2023
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6I4P
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![BU of 6i4p by Molmil](/molmil-images/mine/6i4p) | Crystal structure of the disease-causing G194C mutant of the human dihydrolipoamide dehydrogenase | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dihydrolipoyl dehydrogenase, mitochondrial, ... | Authors: | Szabo, E, Wilk, P, Torocsik, B, Weiss, M.S, Adam-Vizi, V, Ambrus, A. | Deposit date: | 2018-11-10 | Release date: | 2019-11-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants. Hum.Mol.Genet., 28, 2019
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6R4M
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![BU of 6r4m by Molmil](/molmil-images/mine/6r4m) | |
6UDA
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![BU of 6uda by Molmil](/molmil-images/mine/6uda) | Cryo-EM structure of CH235UCA bound to Man5-enriched CH505.N279K.G458Y.SOSIP.664 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CH235 UCA heavy chain Fab, CH235 UCA light chain Fab, ... | Authors: | Henderson, R, Acharya, P. | Deposit date: | 2019-09-19 | Release date: | 2019-10-02 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancester of CH235 lineage CD4bs broadly neutralizing antibodies. Plos Pathog., 15, 2019
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4PFN
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![BU of 4pfn by Molmil](/molmil-images/mine/4pfn) | Crystal structure of Plasmodium vivax SHMT with L-serine Schiff base | Descriptor: | CHLORIDE ION, PYRIDOXAL-5'-PHOSPHATE, SERINE, ... | Authors: | Chitnumsub, P, Jaruwat, A, Leartsakulpanich, U. | Deposit date: | 2014-04-30 | Release date: | 2014-12-17 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of Plasmodium vivax serine hydroxymethyltransferase: implications for ligand-binding specificity and functional control. Acta Crystallogr.,Sect.D, 70, 2014
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8EIR
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![BU of 8eir by Molmil](/molmil-images/mine/8eir) | SARS-CoV-2 polyprotein substrate regulates the stepwise Mpro cleavage reaction | Descriptor: | 3C-like proteinase nsp5, nsp7-nsp10 of Replicase polyprotein 1a | Authors: | Narwal, M, Edwards, T, Armache, J.P, Murakami, K.S. | Deposit date: | 2022-09-15 | Release date: | 2023-04-26 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.49 Å) | Cite: | SARS-CoV-2 polyprotein substrate regulates the stepwise M pro cleavage reaction. J.Biol.Chem., 299, 2023
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8TER
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![BU of 8ter by Molmil](/molmil-images/mine/8ter) | Tropomyosin-receptor kinase fused gene protein (TRK-fused gene protein; TFG) Low Complexity Domain (residues 237-327) P285L mutant, amyloid fiber | Descriptor: | TRK-fused gene protein Low Complexity Domain P285L mutant | Authors: | Rosenberg, G.M, Sawaya, M.R, Boyer, D.R, Ge, P, Abskharon, R, Eisenberg, D.S. | Deposit date: | 2023-07-06 | Release date: | 2023-12-20 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.59 Å) | Cite: | Fibril structures of TFG protein mutants validate the identification of TFG as a disease-related amyloid protein by the IMPAcT method. Pnas Nexus, 2, 2023
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8EKE
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![BU of 8eke by Molmil](/molmil-images/mine/8eke) | |
8TEQ
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![BU of 8teq by Molmil](/molmil-images/mine/8teq) | Tropomyosin-receptor kinase fused gene protein (TRK-fused gene protein; TFG) Low Complexity Domain (residues 237-327) G269V mutant, amyloid fiber | Descriptor: | TRK-fused gene protein Low Complexity Domain G269V mutant | Authors: | Rosenberg, G.M, Sawaya, M.R, Boyer, D.R, Ge, P, Abskharon, R, Eisenberg, D.S. | Deposit date: | 2023-07-06 | Release date: | 2023-12-20 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Fibril structures of TFG protein mutants validate the identification of TFG as a disease-related amyloid protein by the IMPAcT method. Pnas Nexus, 2, 2023
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5XSK
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![BU of 5xsk by Molmil](/molmil-images/mine/5xsk) | Crystal structure of PWWP-DNA complex for human hepatoma-derived growth factor | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(P*TP*GP*GP*TP*CP*TP*TP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*AP*AP*GP*AP*CP*CP*A)-3'), ... | Authors: | Chen, L.Y, Huang, Y.C, Hsieh, Y.C, Lin, P.J, Chen, C.J. | Deposit date: | 2017-06-14 | Release date: | 2018-06-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Structure of PWWP-DNA complex at 2.84 Angstroms resolution To Be Published
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6R95
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![BU of 6r95 by Molmil](/molmil-images/mine/6r95) | |
6R96
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![BU of 6r96 by Molmil](/molmil-images/mine/6r96) | |
8SPZ
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![BU of 8spz by Molmil](/molmil-images/mine/8spz) | Crystal structure of Bax core domain BH3-groove dimer - hexameric fraction with dioctanoyl phosphatidylserine | Descriptor: | Apoptosis regulator BAX, SULFATE ION | Authors: | Cowan, A.D, Colman, P.M, Czabotar, P.E, Miller, M.S. | Deposit date: | 2023-05-04 | Release date: | 2023-12-27 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. Febs J., 291, 2024
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8SVK
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![BU of 8svk by Molmil](/molmil-images/mine/8svk) | Crystal structure of Bax D71N core domain BH3-groove dimer | Descriptor: | Apoptosis regulator BAX, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... | Authors: | Miller, M.S, Czabotar, P.E, Colman, P.M. | Deposit date: | 2023-05-16 | Release date: | 2023-12-27 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. Febs J., 291, 2024
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6UHQ
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![BU of 6uhq by Molmil](/molmil-images/mine/6uhq) | Crystal Structure of C148 mGFP-cDNA-3 | Descriptor: | C148 mGFP-cDNA-3, UNKNOWN LIGAND | Authors: | Winegar, P.W, Hayes, O.G, McMillan, J.R, Figg, C.A, Focia, P.J, Mirkin, C.A. | Deposit date: | 2019-09-27 | Release date: | 2020-03-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | DNA-Directed Protein Packing within Single Crystals. Chem, 6, 2020
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8BW8
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![BU of 8bw8 by Molmil](/molmil-images/mine/8bw8) | |
6RGI
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![BU of 6rgi by Molmil](/molmil-images/mine/6rgi) | Partially unfolded cytochrome c in complex with sulfonatocalix[6]arene | Descriptor: | Cytochrome c iso-1, HEME C, IMIDAZOLE, ... | Authors: | Engilberge, S, Rennie, M.L, Crowley, P.B. | Deposit date: | 2019-04-16 | Release date: | 2019-07-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Calixarene capture of partially unfolded cytochrome c. Febs Lett., 593, 2019
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6RGZ
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![BU of 6rgz by Molmil](/molmil-images/mine/6rgz) | Revisiting pH-gated conformational switch. Complex HK853-RR468 pH 6.5 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Mideros-Mora, C, Casino, P, Marina, A. | Deposit date: | 2019-04-18 | Release date: | 2020-02-19 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Revisiting the pH-gated conformational switch on the activities of HisKA-family histidine kinases. Nat Commun, 11, 2020
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