7R58
Crystal structure of the GPVI-glenzocimab complex
Summary for 7R58
| Entry DOI | 10.2210/pdb7r58/pdb |
| Descriptor | Platelet glycoprotein VI, Fab heavy chain, Fab light chain, ... (7 entities in total) |
| Functional Keywords | blood clotting |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 3 |
| Total formula weight | 71607.71 |
| Authors | Jandrot-Perrus, M.,Lebozec, K.,Rose, N.,Welin, M.,Billiald, P. (deposition date: 2022-02-10, release date: 2022-11-16, Last modification date: 2024-02-07) |
| Primary citation | Billiald, P.,Slater, A.,Welin, M.,Clark, J.C.,Loyau, S.,Pugniere, M.,Jiacomini, I.G.,Rose, N.,Lebozec, K.,Toledano, E.,Francois, D.,Watson, S.P.,Jandrot-Perrus, M. Targeting platelet GPVI with glenzocimab: a novel mechanism for inhibition. Blood Adv, 7:1258-1268, 2023 Cited by PubMed: 36375047DOI: 10.1182/bloodadvances.2022007863 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.902 Å) |
Structure validation
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