8EIR
SARS-CoV-2 polyprotein substrate regulates the stepwise Mpro cleavage reaction
Summary for 8EIR
| Entry DOI | 10.2210/pdb8eir/pdb |
| EMDB information | 28162 |
| Descriptor | 3C-like proteinase nsp5, nsp7-nsp10 of Replicase polyprotein 1a (2 entities in total) |
| Functional Keywords | sars cov-2 main protease (mpro) in complex with the polyprotein substrate, viral protein |
| Biological source | Severe acute respiratory syndrome coronavirus 2 More |
| Total number of polymer chains | 4 |
| Total formula weight | 184170.46 |
| Authors | Narwal, M.,Edwards, T.,Armache, J.P.,Murakami, K.S. (deposition date: 2022-09-15, release date: 2023-04-26, Last modification date: 2023-05-24) |
| Primary citation | Narwal, M.,Armache, J.P.,Edwards, T.J.,Murakami, K.S. SARS-CoV-2 polyprotein substrate regulates the stepwise M pro cleavage reaction. J.Biol.Chem., 299:104697-104697, 2023 Cited by PubMed: 37044215DOI: 10.1016/j.jbc.2023.104697 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.49 Å) |
Structure validation
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