6I8H
 
 | |
4HZ2
 | | Crystal structure of glutathione s-transferase xaut_3756 (target efi-507152) from xanthobacter autotrophicus py2 | | 分子名称: | BENZOIC ACID, GLUTATHIONE, Glutathione S-transferase domain, ... | | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Al Obaidi, N.F, Stead, M, Love, J, Gerlt, J.A, Armstrong, R.N, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2012-11-14 | | 公開日 | 2012-11-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of glutathione s-transferase xaut_3756 from xanthobacter autotrophicus py2
To be Published
|
|
1ICA
 | |
3EH7
 | |
6IJB
 | | Structure of 3-methylmercaptopropionate CoA ligase mutant K523A in complex with AMP and MMPA | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-(methylsulfanyl)propanoic acid, ADENOSINE MONOPHOSPHATE, ... | | 著者 | Shao, X, Cao, H.Y, Wang, P, Li, C.Y, Zhao, F, Peng, M, Chen, X.L, Zhang, Y.Z. | | 登録日 | 2018-10-09 | | 公開日 | 2019-07-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.111 Å) | | 主引用文献 | Mechanistic insight into 3-methylmercaptopropionate metabolism and kinetical regulation of demethylation pathway in marine dimethylsulfoniopropionate-catabolizing bacteria.
Mol.Microbiol., 111, 2019
|
|
3OVJ
 | |
3OVM
 | | X-ray Structural study of quinone reductase II inhibition by compounds with micromolar to nanomolar range IC50 values | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ZINC ION, ... | | 著者 | Pegan, S.D, Sturdy, M, Ferry, G, Delagrange, P, Boutin, J.A. | | 登録日 | 2010-09-16 | | 公開日 | 2011-05-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | X-ray structural studies of quinone reductase 2 nanomolar range inhibitors.
Protein Sci., 20, 2011
|
|
3P6J
 | |
6IK5
 | | Crystal structure of tomato beta-galactosidase (TBG) 4 in complex with galactose | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-galactosidase, ... | | 著者 | Matsuyama, K, Nakae, S, Igarashi, K, Tada, T, Ishimaru, M. | | 登録日 | 2018-10-15 | | 公開日 | 2018-11-28 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Substrate-recognition mechanism of tomato beta-galactosidase 4 using X-ray crystallography and docking simulation.
Planta, 252, 2020
|
|
1I2V
 | | NMR SOLUTION STRUCTURES OF AN ANTIFUNGAL AND ANTIBACTERIAL MUTANT OF HELIOMICIN | | 分子名称: | DEFENSIN HELIOMICIN | | 著者 | Lamberty, M, Caille, A, Landon, C, Tassin-Moindrot, S, Hetru, C, Bulet, P, Vovelle, F. | | 登録日 | 2001-02-12 | | 公開日 | 2002-02-12 | | 最終更新日 | 2021-10-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the antifungal heliomicin and a selected variant with both antibacterial and antifungal activities.
Biochemistry, 40, 2001
|
|
6RS6
 | | X-ray crystal structure of LsAA9B | | 分子名称: | AA9, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Frandsen, K.E.H, Tovborg, M, Poulsen, J.C.N, Johansen, K.S, Lo Leggio, L. | | 登録日 | 2019-05-21 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Insights into an unusual Auxiliary Activity 9 family member lacking the histidine brace motif of lytic polysaccharide monooxygenases.
J.Biol.Chem., 294, 2019
|
|
3EIS
 | |
4MUY
 | | IspH in complex with pyridin-4-ylmethyl diphosphate | | 分子名称: | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, FE3-S4 CLUSTER, pyridin-4-ylmethyl trihydrogen diphosphate | | 著者 | Span, I, Wang, K, Song, Y, Eisenreich, W, Bacher, A, Oldfield, E, Groll, M. | | 登録日 | 2013-09-23 | | 公開日 | 2014-06-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Insights into the Binding of Pyridines to the Iron-Sulfur Enzyme IspH.
J.Am.Chem.Soc., 136, 2014
|
|
3TUL
 | | Crystal structure of N-terminal region of Type III Secretion Major Translocator SipB (residues 82-226) | | 分子名称: | Cell invasion protein sipB | | 著者 | Barta, M.L, Dickenson, N.E, Patel, M, Keightley, J.A, Picking, W.D, Picking, W.L, Geisbrecht, B.V. | | 登録日 | 2011-09-16 | | 公開日 | 2012-02-15 | | 最終更新日 | 2012-03-28 | | 実験手法 | X-RAY DIFFRACTION (2.793 Å) | | 主引用文献 | The Structures of Coiled-Coil Domains from Type III Secretion System Translocators Reveal Homology to Pore-Forming Toxins.
J.Mol.Biol., 417, 2012
|
|
1I2Y
 | | 1.66 A STRUCTURE OF A-DUPLEX WITH BULGED ADENOSINE, SPERMINE FORM | | 分子名称: | DNA/RNA (5'-R(*GP*CP*G)-D(P*AP*TP*AP*T)-R(P*AP*CP*GP*U)-3'), SPERMINE | | 著者 | Tereshko, V, Wallace, S, Usman, N, Wincott, F, Egli, M. | | 登録日 | 2001-02-12 | | 公開日 | 2001-04-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | X-ray crystallographic observation of "in-line" and "adjacent" conformations in a bulged self-cleaving RNA/DNA hybrid.
RNA, 7, 2001
|
|
3E7J
 | |
1I4E
 | | CRYSTAL STRUCTURE OF THE CASPASE-8/P35 COMPLEX | | 分子名称: | Caspase-8, Early 35 kDa protein | | 著者 | Xu, G, Cirilli, M, Huang, Y, Rich, R.L, Myszka, D.G, Wu, H. | | 登録日 | 2001-02-20 | | 公開日 | 2001-03-28 | | 最終更新日 | 2013-09-25 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Covalent inhibition revealed by the crystal structure of the caspase-8/p35 complex.
Nature, 410, 2001
|
|
3P8P
 | | Crystal Structure of Human Dimethylarginine Dimethylaminohydrolase-1 (DDAH-1) variant C274S bound with N5-(1-iminopentyl)-L-ornithine | | 分子名称: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, N~5~-[(1E)-pentanimidoyl]-L-ornithine | | 著者 | Monzingo, A.F, Lluis, M, Wang, Y, Fast, W, Robertus, J.D. | | 登録日 | 2010-10-14 | | 公開日 | 2010-11-10 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Characterization of C-Alkyl Amidines as Bioavailable Covalent Reversible Inhibitors of Human DDAH-1.
Chemmedchem, 6, 2011
|
|
3EA6
 | | Atomic resolution of crystal structure of SEK | | 分子名称: | IODIDE ION, Staphylococcal enterotoxin K, ZINC ION | | 著者 | Shi, K, Huseby, M, Schlievert, P.M, Ohlendorf, D.H, Earhart, C.A. | | 登録日 | 2008-08-24 | | 公開日 | 2009-06-30 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (0.92 Å) | | 主引用文献 | Structural Studies of an Emerging Pyrogenic Superantigen, SEK
To be Published
|
|
4I1K
 | | Crystal Structure of VRN1 (Residues 208-341) | | 分子名称: | B3 domain-containing transcription factor VRN1, CHLORIDE ION | | 著者 | King, G, Chanson, A.H, McCallum, E.J, Ohme-Takagi, M, Byriel, K, Hill, J.M, Martin, J.L, Mylne, J.S. | | 登録日 | 2012-11-21 | | 公開日 | 2012-12-19 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The Arabidopsis B3 Domain Protein VERNALIZATION1 (VRN1) Is Involved in Processes Essential for Development, with Structural and Mutational Studies Revealing Its DNA-binding Surface.
J.Biol.Chem., 288, 2013
|
|
3OY3
 | | Crystal structure of ABL T315I mutant kinase domain bound with a DFG-out inhibitor AP24589 | | 分子名称: | 5-[(5-{[4-{[4-(2-hydroxyethyl)piperazin-1-yl]methyl}-3-(trifluoromethyl)phenyl]carbamoyl}-2-methylphenyl)ethynyl]-1-methyl-1H-imidazole-2-carboxamide, Tyrosine-protein kinase ABL1 | | 著者 | Zhou, T, Commodore, L, Huang, W.S, Wang, Y, Thomas, M, Keats, J, Xu, Q, Rivera, V, Shakespeare, W.C, Clackson, T, Dalgarno, D.C, Zhu, X. | | 登録日 | 2010-09-22 | | 公開日 | 2010-12-15 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural Mechanism of the Pan-BCR-ABL Inhibitor Ponatinib (AP24534): Lessons for Overcoming Kinase Inhibitor Resistance.
Chem.Biol.Drug Des., 77, 2011
|
|
6IC2
 | | Polypharmacology of Epacadostat: a Potent and Selective Inhibitor of the Tumor Associated Carbonic Anhydrases IX and XII | | 分子名称: | Carbonic anhydrase 2, N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-{[2-(sulfamoylamino)ethyl]amino}-1,2,5-oxadiazole-3-carboximidamide, ZINC ION | | 著者 | Angeli, A, Ferraroni, M, Supuran, C.T, Carta, F. | | 登録日 | 2018-12-01 | | 公開日 | 2019-05-15 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Polypharmacology of epacadostat: a potent and selective inhibitor of the tumor associated carbonic anhydrases IX and XII.
Chem.Commun.(Camb.), 55, 2019
|
|
4I2A
 | |
4I2B
 | | Ternary complex of mouse TdT with ssDNA and AMPcPP | | 分子名称: | 5'-D(P*AP*AP*AP*AP*A)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA nucleotidylexotransferase, ... | | 著者 | Gouge, J, Delarue, M. | | 登録日 | 2012-11-21 | | 公開日 | 2013-07-24 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
|
|
2YN3
 | | Structural insight into the giant calcium-binding adhesin SiiE: implications for the adhesion of Salmonella enterica to polarized epithelial cells | | 分子名称: | CALCIUM ION, IODIDE ION, PHOSPHATE ION, ... | | 著者 | Griessl, M.H, Schmid, B, Kassler, K, Braunsmann, C, Ritter, R, Barlag, B, Sturm, K.U, Danzer, C, Wagner, C, Schaeffer, T.E, Sticht, H, Hensel, M, Muller, Y.A. | | 登録日 | 2012-10-11 | | 公開日 | 2013-04-03 | | 最終更新日 | 2013-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Structural Insight Into the Giant Ca(2+)-Binding Adhesin Siie: Implications for the Adhesion of Salmonella Enterica to Polarized Epithelial Cells.
Structure, 21, 2013
|
|
