1I4E

CRYSTAL STRUCTURE OF THE CASPASE-8/P35 COMPLEX

Summary for 1I4E

• Entry DOI: 10.2210/pdb1i4e/pdb
• Descriptor: Early 35 kDa protein, Caspase-8 (2 entities in total)
• Functional Keywords: covalent complex protease-inhibitor, apoptosis-hydrolase complex, apoptosis/hydrolase
• Biological source: Autographa californica nucleopolyhedrovirus (AcMNPV); More
• Cellular location: Cytoplasm: Q14790
• Total number of polymer chains: 2
• Total formula weight: 64291.10

Authors

Xu, G.,Cirilli, M.,Huang, Y.,Rich, R.L.,Myszka, D.G.,Wu, H. (deposition date: 2001-02-20, release date: 2001-03-28, Last modification date: 2013-09-25)

• Primary citation: Xu, G.,Cirilli, M.,Huang, Y.,Rich, R.L.,Myszka, D.G.,Wu, H.; Covalent inhibition revealed by the crystal structure of the caspase-8/p35 complex.; Nature, 410:494-497, 2001; PubMed: 11260720; DOI: 10.1038/35068604

Experimental method

X-RAY DIFFRACTION (3 Å)