1ICA
REFINED THREE-DIMENSIONAL STRUCTURE OF INSECT DEFENSIN A
Summary for 1ICA
| Entry DOI | 10.2210/pdb1ica/pdb |
| Descriptor | INSECT DEFENSIN A (1 entity in total) |
| Functional Keywords | antibacterial protein |
| Biological source | Protophormia terraenovae |
| Total number of polymer chains | 1 |
| Total formula weight | 4072.69 |
| Authors | Cornet, B.,Bonmatin, J.M.,Ptak, M.,Vovelle, F. (deposition date: 1994-12-16, release date: 1995-07-10, Last modification date: 2024-10-09) |
| Primary citation | Cornet, B.,Bonmatin, J.M.,Hetru, C.,Hoffmann, J.A.,Ptak, M.,Vovelle, F. Refined three-dimensional solution structure of insect defensin A. Structure, 3:435-448, 1995 Cited by PubMed Abstract: Insect defensin A is a basic 4 kDa protein secreted by Phormia terranovae larvae in response to bacterial challenges or injuries. Previous biological tests suggest that the bacterial cytoplasmic membrane is the target of defensin A. The structural study of this protein is the first step towards establishing a structure-activity relationship and forms the basis for understanding its antibiotic activity at the molecular level. PubMed: 7663941DOI: 10.1016/S0969-2126(01)00177-0 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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