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3OVJ

Structure of an amyloid forming peptide KLVFFA from amyloid beta in complex with orange G

Summary for 3OVJ
Entry DOI10.2210/pdb3ovj/pdb
Related3OW9
DescriptorKLVFFA hexapeptide segment from Amyloid beta, 7-hydroxy-8-[(E)-phenyldiazenyl]naphthalene-1,3-disulfonic acid (3 entities in total)
Functional Keywordsamyloid-like protofibril, protein fibril
Cellular locationMembrane; Single-pass type I membrane protein: P05067
Total number of polymer chains4
Total formula weight3716.45
Authors
Landau, M.,Eisenberg, D. (deposition date: 2010-09-16, release date: 2011-07-06, Last modification date: 2024-02-21)
Primary citationLandau, M.,Sawaya, M.R.,Faull, K.F.,Laganowsky, A.,Jiang, L.,Sievers, S.A.,Liu, J.,Barrio, J.R.,Eisenberg, D.
Towards a pharmacophore for amyloid.
Plos Biol., 9:e1001080-e1001080, 2011
Cited by
PubMed: 21695112
DOI: 10.1371/journal.pbio.1001080
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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