8DUB
| Estrogen Receptor Alpha Ligand Binding Domain in Complex with ((1'-(4-((1-ethylpyrrolidin-3-yl)methyl)phenyl)-6'-hydroxy-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone | 分子名称: | Estrogen receptor, [(1'R)-1'-(4-{[(3S)-1-ethylpyrrolidin-3-yl]oxy}phenyl)-6'-hydroxy-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl](phenyl)methanone | 著者 | Hancock, G.R, Young, K.S, Hosfield, D.J, Joiner, C, Sullivan, E.A, Yildz, Y, Laine, M, Greene, G.L, Fanning, S.W. | 登録日 | 2022-07-27 | 公開日 | 2022-11-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells. NPJ Breast Cancer, 8, 2022
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7QH6
| Cryo-EM structure of the human mtLSU assembly intermediate upon MRM2 depletion - class 1 | 分子名称: | 16S ribosomal RNA, 39S ribosomal protein L13, mitochondrial, ... | 著者 | Rebelo-Guiomar, P, Pellegrino, S, Dent, K.C, Warren, A.J, Minczuk, M. | 登録日 | 2021-12-10 | 公開日 | 2022-03-02 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit. Nat Commun, 13, 2022
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161D
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7QWR
| Structure of the ribosome-nascent chain containing an ER signal sequence in complex with NAC | 分子名称: | 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E. | 登録日 | 2022-01-25 | 公開日 | 2022-03-09 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting. Science, 375, 2022
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8E4C
| IgM BCR fab truncated form | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, B-cell antigen receptor complex-associated protein alpha chain,Yellow fluorescent protein, B-cell antigen receptor complex-associated protein beta chain, ... | 著者 | Dong, Y, Pi, X, Wu, H, Reth, M. | 登録日 | 2022-08-18 | 公開日 | 2022-11-16 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural principles of B cell antigen receptor assembly. Nature, 612, 2022
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5K3V
| apo-PDX1.3 (Arabidopsis) | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Pyridoxal 5'-phosphate synthase subunit PDX1.3, ... | 著者 | Robinson, G.C, Kaufmann, M, Roux, C, Fitzpatrick, T.B. | 登録日 | 2016-05-20 | 公開日 | 2016-10-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural definition of the lysine swing in Arabidopsis thaliana PDX1: Intermediate channeling facilitating vitamin B6 biosynthesis. Proc.Natl.Acad.Sci.USA, 113, 2016
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5JTG
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3CI4
| Structure of the PduO-type ATP:co(I)rrinoid adenosyltransferase from Lactobacillus reuteri complexed with four-coordinate cob(II)inamide and ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, COB(II)INAMIDE, Cobalamin adenosyltransferase PduO-like protein, ... | 著者 | Maurice, M.St, Mera, P.E, Escalante-Semerena, J.C, Rayment, I. | 登録日 | 2008-03-10 | 公開日 | 2008-05-27 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural characterization of a human-type corrinoid adenosyltransferase confirms that coenzyme B12 is synthesized through a four-coordinate intermediate. Biochemistry, 47, 2008
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5FRD
| Structure of a thermophilic esterase | 分子名称: | CARBOXYLESTERASE (EST-2), CHLORIDE ION, CITRATE ANION, ... | 著者 | Sayer, C, Finnigan, W, Isupov, M.N, Levisson, M, Kengen, S.W.M, van der Oost, J, Harmer, N, Littlechild, J.A. | 登録日 | 2015-12-17 | 公開日 | 2016-05-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural and Biochemical Characterisation of Archaeoglobus Fulgidus Esterase Reveals a Bound Coa Molecule in the Vicinity of the Active Site. Sci.Rep., 6, 2016
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5JU9
| Structure of a beta-1,4-mannanase, SsGH134, in complex with Man3. | 分子名称: | CHLORIDE ION, beta-1,4-mannanase, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose | 著者 | Jin, Y, Petricevic, M, Goddard-Borger, E.D, Williams, S.J, Davies, G.J. | 登録日 | 2016-05-10 | 公開日 | 2016-11-16 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | 主引用文献 | A beta-Mannanase with a Lysozyme-like Fold and a Novel Molecular Catalytic Mechanism. ACS Cent Sci, 2, 2016
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5SVK
| Crystal structure of the ATP-gated human P2X3 ion channel in the ATP-bound, open state | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Mansoor, S.E, Lu, W, Oosterheert, W, Shekhar, M, Tajkhorshid, E, Gouaux, E. | 登録日 | 2016-08-06 | 公開日 | 2016-09-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.773 Å) | 主引用文献 | X-ray structures define human P2X3 receptor gating cycle and antagonist action. Nature, 538, 2016
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8DR5
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6QGB
| Crystal structure of Ideonella sakaiensis MHETase bound to benzoic acid | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, BENZOIC ACID, CALCIUM ION, ... | 著者 | Palm, G.J, Reisky, L, Boettcher, D, Mueller, H, Michels, E.A.P, Walczak, C, Berndt, L, Weiss, M.S, Bornscheuer, U.T, Weber, G. | 登録日 | 2019-01-10 | 公開日 | 2019-04-03 | 最終更新日 | 2019-04-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate. Nat Commun, 10, 2019
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5SVT
| Anomalous Cs+ signal reveals the site of Na+ ion entry to the channel pore of the human P2X3 ion channel through the extracellular fenestrations | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, P2X purinoceptor 3, ... | 著者 | Mansoor, S.E, Lu, W, Oosterheert, W, Shekhar, M, Tajkhorshid, E, Gouaux, E. | 登録日 | 2016-08-07 | 公開日 | 2016-09-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.794 Å) | 主引用文献 | X-ray structures define human P2X3 receptor gating cycle and antagonist action. Nature, 538, 2016
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5SW1
| Thaumatin Structure at pH 6.0 | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Thaumatin I | 著者 | Masuda, T, Sano, A, Murata, K, Okubo, K, Suzuki, M, Mikami, B. | 登録日 | 2016-08-08 | 公開日 | 2017-08-09 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Thaumatin Structure at pH 6.0 To Be Published
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5FSD
| 1.75 A resolution 2,5-dihydroxybenzensulfonate inhibited Sporosarcina pasteurii urease | 分子名称: | 1,2-ETHANEDIOL, 2,5-dihydroxybenzenesulfonic acid, HYDROXIDE ION, ... | 著者 | Mazzei, L, Cianci, M, Musiani, F, Ciurli, S. | 登録日 | 2016-01-04 | 公開日 | 2016-03-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Inactivation of Urease by 1,4-Benzoquinone: Chemistry at the Protein Surface. Dalton Trans, 45, 2016
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5FUY
| catalytic domain of Thymidine kinase from Trypanosoma brucei with dTMP | 分子名称: | PHOSPHATE ION, THYMDINE KINASE, ZINC ION, ... | 著者 | Timm, J, Valente, M, Castillo-Acosta, V, Balzarini, T, Nettleship, J.E, Rada, H, Wilson, K.S, Gonzalez-Pacanowska, D. | 登録日 | 2016-01-31 | 公開日 | 2016-07-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Cell Cycle Regulation and Novel Structural Features of Thymidine Kinase, an Essential Enzyme in Trypanosoma Brucei. Mol.Microbiol., 102, 2016
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7QWS
| Structure of ribosome translating beta-tubulin in complex with TTC5 and NAC | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E. | 登録日 | 2022-01-25 | 公開日 | 2022-03-09 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting. Science, 375, 2022
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8DR1
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1A1S
| ORNITHINE CARBAMOYLTRANSFERASE FROM PYROCOCCUS FURIOSUS | 分子名称: | ORNITHINE CARBAMOYLTRANSFERASE | 著者 | Villeret, V, Clantin, B, Tricot, C, Legrain, C, Roovers, M, Stalon, V, Glansdorff, N, Van Beeumen, J. | 登録日 | 1997-12-15 | 公開日 | 1998-06-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The crystal structure of Pyrococcus furiosus ornithine carbamoyltransferase reveals a key role for oligomerization in enzyme stability at extremely high temperatures. Proc.Natl.Acad.Sci.USA, 95, 1998
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1CAG
| CRYSTAL AND MOLECULAR STRUCTURE OF A COLLAGEN-LIKE PEPTIDE AT 1.9 ANGSTROM RESOLUTION | 分子名称: | ACETIC ACID, COLLAGEN-LIKE PEPTIDE | 著者 | Bella, J, Eaton, M, Brodsky, B, Berman, H.M. | 登録日 | 1994-03-29 | 公開日 | 1994-11-01 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal and molecular structure of a collagen-like peptide at 1.9 A resolution. Science, 266, 1994
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8EAQ
| Structure of the full-length IP3R1 channel determined at high Ca2+ | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, CALCIUM ION, Inositol 1,4,5-trisphosphate receptor type 1, ... | 著者 | Fan, G, Baker, M.R, Terry, L.E, Arige, V, Chen, M, Seryshev, A.B, Baker, M.L, Ludtke, S.J, Yule, D.I, Serysheva, I.I. | 登録日 | 2022-08-29 | 公開日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Conformational motions and ligand-binding underlying gating and regulation in IP 3 R channel. Nat Commun, 13, 2022
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5FHZ
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5JWS
| T4 Lysozyme L99A with 1-Hydro-2-ethyl-1,2-azaborine Bound | 分子名称: | 2-ethyl-1,2-dihydro-1,2-azaborinine, CHLORIDE ION, Endolysin | 著者 | Lee, H, Fischer, M, Shoichet, B.K, Liu, S.-Y. | 登録日 | 2016-05-12 | 公開日 | 2016-09-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Hydrogen Bonding of 1,2-Azaborines in the Binding Cavity of T4 Lysozyme Mutants: Structures and Thermodynamics. J.Am.Chem.Soc., 138, 2016
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8EAR
| Structure of the full-length IP3R1 channel determined in the presence of Calcium/IP3/ATP | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | 著者 | Fan, G, Baker, M.R, Terry, L.E, Arige, V, Chen, M, Seryshev, A.B, Baker, M.L, Ludtke, S.J, Yule, D.I, Serysheva, I.I. | 登録日 | 2022-08-29 | 公開日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Conformational motions and ligand-binding underlying gating and regulation in IP 3 R channel. Nat Commun, 13, 2022
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