8EAQ

Structure of the full-length IP3R1 channel determined at high Ca2+

This is a non-PDB format compatible entry.

Summary for 8EAQ

• Entry DOI: 10.2210/pdb8eaq/pdb
• EMDB information: 27982
• Descriptor: Inositol 1,4,5-trisphosphate receptor type 1, ZINC ION, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: calcium channel, lipid nanodisc, membrane protein
• Biological source: Rattus norvegicus (Norway rat)
• Total number of polymer chains: 4
• Total formula weight: 1277172.52

Authors

Fan, G.,Baker, M.R.,Terry, L.E.,Arige, V.,Chen, M.,Seryshev, A.B.,Baker, M.L.,Ludtke, S.J.,Yule, D.I.,Serysheva, I.I. (deposition date: 2022-08-29, release date: 2022-11-23)

• Primary citation: Fan, G.,Baker, M.R.,Terry, L.E.,Arige, V.,Chen, M.,Seryshev, A.B.,Baker, M.L.,Ludtke, S.J.,Yule, D.I.,Serysheva, I.I.; Conformational motions and ligand-binding underlying gating and regulation in IP 3 R channel.; Nat Commun, 13:6942-6942, 2022; PubMed: 36376291; DOI: 10.1038/s41467-022-34574-1

Experimental method

ELECTRON MICROSCOPY (3.26 Å)