7QH6
Cryo-EM structure of the human mtLSU assembly intermediate upon MRM2 depletion - class 1
Summary for 7QH6
Entry DOI | 10.2210/pdb7qh6/pdb |
EMDB information | 13962 13963 13965 13966 13967 |
Descriptor | 39S ribosomal protein L2, mitochondrial, 39S ribosomal protein L18, mitochondrial, 39S ribosomal protein L19, mitochondrial, ... (47 entities in total) |
Functional Keywords | mitochondria, ribosome, assembly, methyltransferase, mrm2, rna modification |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 46 |
Total formula weight | 1607022.67 |
Authors | Rebelo-Guiomar, P.,Pellegrino, S.,Dent, K.C.,Warren, A.J.,Minczuk, M. (deposition date: 2021-12-10, release date: 2022-03-02, Last modification date: 2024-07-17) |
Primary citation | Rebelo-Guiomar, P.,Pellegrino, S.,Dent, K.C.,Sas-Chen, A.,Miller-Fleming, L.,Garone, C.,Van Haute, L.,Rogan, J.F.,Dinan, A.,Firth, A.E.,Andrews, B.,Whitworth, A.J.,Schwartz, S.,Warren, A.J.,Minczuk, M. A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit. Nat Commun, 13:929-929, 2022 Cited by PubMed: 35177605DOI: 10.1038/s41467-022-28503-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.08 Å) |
Structure validation
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