6HIT
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![BU of 6hit by Molmil](/molmil-images/mine/6hit) | The crystal structure of haemoglobin from Atlantic cod | 分子名称: | Hemoglobin alpha 2 chain, Hemoglobin beta 4 chain, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Helland, R, Bjorkeng, E.K, Rothweiler, U, Sydnes, M.O, Pampanin, D.M. | 登録日 | 2018-08-30 | 公開日 | 2019-08-21 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The crystal structure of haemoglobin from Atlantic cod. Acta Crystallogr.,Sect.F, 75, 2019
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3E2U
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![BU of 3e2u by Molmil](/molmil-images/mine/3e2u) | Crystal structure of the zink-knuckle 2 domain of human CLIP-170 in complex with CAP-Gly domain of human dynactin-1 (p150-GLUED) | 分子名称: | CAP-Gly domain-containing linker protein 1, Dynactin subunit 1, ZINC ION | 著者 | Weisbrich, A, Honnappa, S, Capitani, G, Steinmetz, M.O. | 登録日 | 2008-08-06 | 公開日 | 2008-08-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-function relationship of CAP-Gly domains Nat.Struct.Mol.Biol., 14, 2007
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6HX8
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![BU of 6hx8 by Molmil](/molmil-images/mine/6hx8) | Tubulin-STX3451 complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Dohle, W, Prota, A.E, Menchon, G, Hamel, E, Steinmetz, M.O, Potter, B.V.L. | 登録日 | 2018-10-16 | 公開日 | 2019-02-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | 主引用文献 | Tetrahydroisoquinoline Sulfamates as Potent Microtubule Disruptors: Synthesis, Antiproliferative and Antitubulin Activity of Dichlorobenzyl-Based Derivatives, and a Tubulin Cocrystal Structure. ACS Omega, 4, 2019
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1IK3
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![BU of 1ik3 by Molmil](/molmil-images/mine/1ik3) | LIPOXYGENASE-3 (SOYBEAN) COMPLEX WITH 13(S)-HYDROPEROXY-9(Z),11(E)-OCTADECADIENOIC ACID | 分子名称: | (TRANS-12,13-EPOXY)-11-HYDROXY-9(Z)-OCTADECENOIC ACID, (TRANS-12,13-EPOXY)-9-HYDROXY-10(E)-OCTADECENOIC ACID, 13(R)-HYDROPEROXY-9(Z),11(E)-OCTADECADIENOIC ACID, ... | 著者 | Skrzypczak-Jankun, E, Funk Jr, M.O. | 登録日 | 2001-05-01 | 公開日 | 2001-11-14 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Three-dimensional structure of a purple lipoxygenase. J.Am.Chem.Soc., 123, 2001
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4C0M
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![BU of 4c0m by Molmil](/molmil-images/mine/4c0m) | Crystal Structure of the N terminal domain of wild type TRIF (TIR- domain-containing adapter-inducing interferon-beta) | 分子名称: | TIR DOMAIN-CONTAINING ADAPTER MOLECULE 1 | 著者 | Ullah, M.O, Ve, T, Mangan, M, Alaidarous, M, Sweet, M.J, Mansell, A, Kobe, B. | 登録日 | 2013-08-05 | 公開日 | 2013-12-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The Tlr Signalling Adaptor Trif/Ticam-1 Has an N-Terminal Helical Domain with Structural Similarity to Ifit Proteins Acta Crystallogr.,Sect.D, 69, 2013
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4TV9
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![BU of 4tv9 by Molmil](/molmil-images/mine/4tv9) | Tubulin-PM060184 complex | 分子名称: | (1Z,4S,6Z)-1-[(N-{(2Z,4Z,6E,8S)-8-[(2S)-5-methoxy-6-oxo-3,6-dihydro-2H-pyran-2-yl]-6-methylnona-2,4,6-trienoyl}-3-methy l-L-valyl)amino]octa-1,6-dien-4-yl carbamate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Prota, A.E, Bargsten, K, Diaz, J.F, Marsh, M, Cuevas, C, Liniger, M, Neuhaus, C, Andreu, J.M, Altmann, K.H, Steinmetz, M.O. | 登録日 | 2014-06-26 | 公開日 | 2014-08-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs. Proc.Natl.Acad.Sci.USA, 111, 2014
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4TUY
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![BU of 4tuy by Molmil](/molmil-images/mine/4tuy) | Tubulin-Rhizoxin complex | 分子名称: | (1R,2R,3E,5R,7R,8S,10S,13E,16R)-8-hydroxy-10-[(2S,3R,4E,6E,8E)-3-methoxy-4,8-dimethyl-9-(2-methyl-1,3-oxazol-4-yl)nona-4,6,8-trien-2-yl]-2,7-dimethyl-6,11,19-trioxatricyclo[14.3.1.0~5,7~]icosa-3,13-diene-12,18-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Prota, A.E, Bargsten, K, Diaz, J.F, Marsh, M, Cuevas, C, Liniger, M, Neuhaus, C, Andreu, J.M, Altmann, K.H, Steinmetz, M.O. | 登録日 | 2014-06-25 | 公開日 | 2014-08-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs. Proc.Natl.Acad.Sci.USA, 111, 2014
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5NQT
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![BU of 5nqt by Molmil](/molmil-images/mine/5nqt) | Tubulin Darpin room-temperature structure determined by serial millisecond crystallography | 分子名称: | DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Weinert, T, Olieric, N, James, D, Gashi, D, Nogly, P, Jaeger, K, Steinmetz, M.O, Standfuss, J. | 登録日 | 2017-04-21 | 公開日 | 2017-09-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons. Nat Commun, 8, 2017
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4TV8
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![BU of 4tv8 by Molmil](/molmil-images/mine/4tv8) | Tubulin-Maytansine complex | 分子名称: | (3beta,4beta,5beta,10beta,11E,13E)-maytansine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Prota, A.E, Bargsten, K, Diaz, J.F, Marsh, M, Cuevas, C, Liniger, M, Neuhaus, C, Andreu, J.M, Altmann, K.H, Steinmetz, M.O. | 登録日 | 2014-06-26 | 公開日 | 2014-08-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.103 Å) | 主引用文献 | A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs. Proc.Natl.Acad.Sci.USA, 111, 2014
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5OSK
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![BU of 5osk by Molmil](/molmil-images/mine/5osk) | Tubulin-7j complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-(2,5-Dimethoxybenzyl)-7-sulfamoyloxy-6-methoxy-3,4-dihydroquinazolin-2(1H)-one, CALCIUM ION, ... | 著者 | Menchon, G, Prota, A.E, Steinmetz, M.O, Potter, B.V.L. | 登録日 | 2017-08-17 | 公開日 | 2017-12-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure. J. Med. Chem., 61, 2018
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5O7A
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![BU of 5o7a by Molmil](/molmil-images/mine/5o7a) | Quinolin-6-yloxyacetamides are microtubule destabilizing agents that bind to the colchicine site of tubulin | 分子名称: | (2~{R})-2-(3-ethynylquinolin-6-yl)oxy-2-methoxy-~{N}-[(1~{E})-1-methoxyimino-2-methyl-propan-2-yl]ethanamide, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Sharma, A, Olieric, N, Steinmetz, M.O. | 登録日 | 2017-06-08 | 公開日 | 2017-07-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.495 Å) | 主引用文献 | Quinolin-6-Yloxyacetamides Are Microtubule Destabilizing Agents That Bind to the Colchicine Site of Tubulin. Int J Mol Sci, 18, 2017
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3ZZP
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![BU of 3zzp by Molmil](/molmil-images/mine/3zzp) | Circular permutant of ribosomal protein S6, lacking edge strand beta- 2 of wild-type S6. | 分子名称: | RIBOSOMAL PROTEIN S6 | 著者 | Saraboji, K, Haglund, E, Lindberg, M.O, Oliveberg, M, Logan, D.T. | 登録日 | 2011-09-02 | 公開日 | 2011-11-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (0.96 Å) | 主引用文献 | Trimming Down a Protein Structure to its Bare Foldons: Spatial Organization of the Cooperative Unit. J.Biol.Chem., 287, 2012
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4BSX
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![BU of 4bsx by Molmil](/molmil-images/mine/4bsx) | Crystal Structure of the N terminal domain of TRIF (TIR-domain- containing adapter-inducing interferon-beta) | 分子名称: | TIR DOMAIN-CONTAINING ADAPTER MOLECULE 1 | 著者 | Ullah, M.O, Ve, T, Mangan, M, Alaidarous, M, Sweet, M.J, Mansell, A, Kobe, B. | 登録日 | 2013-06-12 | 公開日 | 2013-12-11 | 最終更新日 | 2013-12-18 | 実験手法 | X-RAY DIFFRACTION (2.229 Å) | 主引用文献 | The Tlr Signalling Adaptor Trif/Ticam-1 Has an N-Terminal Helical Domain with Structural Similarity to Ifit Proteins Acta Crystallogr.,Sect.D, 69, 2013
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4C7M
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![BU of 4c7m by Molmil](/molmil-images/mine/4c7m) | The crystal structure of TcpB or BtpA TIR domain | 分子名称: | Toll/interleukin-1 receptor domain-containing protein | 著者 | Alaidarous, M, Ve, T, Casey, L.W, Valkov, E, Ullah, M.O, Schembri, M.A, Mansell, A, Sweet, M.J, Kobe, B. | 登録日 | 2013-09-23 | 公開日 | 2013-12-04 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | Mechanism of bacterial interference with TLR4 signaling by Brucella Toll/interleukin-1 receptor domain-containing protein TcpB. J.Biol.Chem., 289, 2014
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5OW5
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![BU of 5ow5 by Molmil](/molmil-images/mine/5ow5) | p60p80-CAMSAP complex | 分子名称: | 1,2-ETHANEDIOL, Calmodulin-regulated spectrin-associated protein, DI(HYDROXYETHYL)ETHER, ... | 著者 | Rezabkova, L, Capitani, G, Prota, A.E, Kammerer, R.A, Steinmetz, M.O. | 登録日 | 2017-08-30 | 公開日 | 2018-07-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Basis of Formation of the Microtubule Minus-End-Regulating CAMSAP-Katanin Complex. Structure, 26, 2018
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5D3A
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5DCW
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![BU of 5dcw by Molmil](/molmil-images/mine/5dcw) | Iridoid synthase from Catharanthus roseus - ligand free structure | 分子名称: | 1,2-ETHANEDIOL, Iridoid synthase | 著者 | Caputi, L, Kries, H, Stevenson, C.E.M, Kamileen, M.O, Sherden, N.H, Geu-Flores, F, Lawson, D.M, O'Connor, S.E. | 登録日 | 2015-08-24 | 公開日 | 2015-10-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural determinants of reductive terpene cyclization in iridoid biosynthesis. Nat.Chem.Biol., 12, 2016
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5DCU
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![BU of 5dcu by Molmil](/molmil-images/mine/5dcu) | Iridoid synthase from Catharanthus roseus - ternary complex with NADP+ and triethylene glycol carboxylic acid | 分子名称: | 1,2-ETHANEDIOL, Iridoid synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Caputi, L, Kries, H, Stevenson, C.E.M, Kamileen, M.O, Sherden, N.H, Geu-Flores, F, Lawson, D.M, O'Connor, S.E. | 登録日 | 2015-08-24 | 公開日 | 2015-10-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural determinants of reductive terpene cyclization in iridoid biosynthesis. Nat.Chem.Biol., 12, 2016
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5DF1
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![BU of 5df1 by Molmil](/molmil-images/mine/5df1) | Iridoid synthase from Catharanthus roseus - ternary complex with NADP+ and geranic acid | 分子名称: | (2E)-3,7-dimethylocta-2,6-dienoic acid, 1,2-ETHANEDIOL, IMIDAZOLE, ... | 著者 | Caputi, L, Kries, H, Stevenson, C.E.M, Kamileen, M.O, Sherden, N.H, Geu-Flores, F, Lawson, D.M, O'Connor, S.E. | 登録日 | 2015-08-26 | 公開日 | 2015-10-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural determinants of reductive terpene cyclization in iridoid biosynthesis. Nat.Chem.Biol., 12, 2016
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5DCY
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![BU of 5dcy by Molmil](/molmil-images/mine/5dcy) | Iridoid synthase G150A mutant from Catharanthus roseus - binary complex with NADP+ | 分子名称: | 1,2-ETHANEDIOL, Iridoid synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Caputi, L, Kries, H, Stevenson, C.E.M, Kamileen, M.O, Sherden, N.H, Geu-Flores, F, Lawson, D.M, O'Connor, S.E. | 登録日 | 2015-08-24 | 公開日 | 2015-10-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structural determinants of reductive terpene cyclization in iridoid biosynthesis. Nat.Chem.Biol., 12, 2016
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6Y6D
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![BU of 6y6d by Molmil](/molmil-images/mine/6y6d) | Tubulin-7-Aminonoscapine complex | 分子名称: | (3~{S})-7-azanyl-6-methoxy-3-[(5~{R})-4-methoxy-6-methyl-7,8-dihydro-5~{H}-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3~{H}-2-benzofuran-1-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Oliva, M.A, Prota, A.E, Rodriguez-Salarichs, J, Gu, W, Bennani, Y.L, Jimenez-Barbero, J, Canales, A, Steinmetz, M.O, Diaz, J.F. | 登録日 | 2020-02-26 | 公開日 | 2020-07-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Basis of Noscapine Activation for Tubulin Binding. J.Med.Chem., 63, 2020
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7AG9
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2HKN
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2HL3
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2HKQ
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![BU of 2hkq by Molmil](/molmil-images/mine/2hkq) | |