4C7M

The crystal structure of TcpB or BtpA TIR domain

Summary for 4C7M

Entry DOI	10.2210/pdb4c7m/pdb
Descriptor	Toll/interleukin-1 receptor domain-containing protein (2 entities in total)
Functional Keywords	signaling protein, protein
Biological source	Brucella melitensis
Total number of polymer chains	4
Total formula weight	60240.48
Authors	Alaidarous, M.,Ve, T.,Casey, L.W.,Valkov, E.,Ullah, M.O.,Schembri, M.A.,Mansell, A.,Sweet, M.J.,Kobe, B. (deposition date: 2013-09-23, release date: 2013-12-04, Last modification date: 2023-12-20)
Primary citation	Alaidarous, M.,Ve, T.,Casey, L.W.,Valkov, E.,Ericsson, D.J.,Ullah, M.O.,Schembri, M.A.,Mansell, A.,Sweet, M.J.,Kobe, B. Mechanism of bacterial interference with TLR4 signaling by Brucella Toll/interleukin-1 receptor domain-containing protein TcpB. J.Biol.Chem., 289:654-668, 2014 Cited by PubMed: 24265315 DOI: 10.1074/jbc.M113.523274 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.57 Å)

Structure validation