5DCY

Iridoid synthase G150A mutant from Catharanthus roseus - binary complex with NADP+

Summary for 5DCY

Entry DOI	10.2210/pdb5dcy/pdb
Descriptor	Iridoid synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TRIETHYLENE GLYCOL, ... (5 entities in total)
Functional Keywords	iridoid synthase, short chain dehydrogenase, nadph-dependent, catharanthus roseus, oxidoreductase
Biological source	Catharanthus roseus (Madagascar periwinkle)
Cellular location	Cytoplasm, cytosol : K7WDL7
Total number of polymer chains	2
Total formula weight	85036.70
Authors	Caputi, L.,Kries, H.,Stevenson, C.E.M.,Kamileen, M.O.,Sherden, N.H.,Geu-Flores, F.,Lawson, D.M.,O'Connor, S.E. (deposition date: 2015-08-24, release date: 2015-10-28, Last modification date: 2024-01-10)
Primary citation	Kries, H.,Caputi, L.,Stevenson, C.E.,Kamileen, M.O.,Sherden, N.H.,Geu-Flores, F.,Lawson, D.M.,O'Connor, S.E. Structural determinants of reductive terpene cyclization in iridoid biosynthesis. Nat.Chem.Biol., 12:6-8, 2016 Cited by PubMed: 26551396 DOI: 10.1038/nchembio.1955 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation