6Y6D

Tubulin-7-Aminonoscapine complex

Summary for 6Y6D

Entry DOI	10.2210/pdb6y6d/pdb
Descriptor	Tubulin alpha-1B chain, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ... (13 entities in total)
Functional Keywords	cell cycle, tubulin fold, cytoskeleton, microtubule
Biological source	Rattus norvegicus (Norway rat) More
Total number of polymer chains	6
Total formula weight	265355.12
Authors	Oliva, M.A.,Prota, A.E.,Rodriguez-Salarichs, J.,Gu, W.,Bennani, Y.L.,Jimenez-Barbero, J.,Canales, A.,Steinmetz, M.O.,Diaz, J.F. (deposition date: 2020-02-26, release date: 2020-07-22, Last modification date: 2024-01-24)
Primary citation	Oliva, M.A.,Prota, A.E.,Rodriguez-Salarichs, J.,Bennani, Y.L.,Jimenez-Barbero, J.,Bargsten, K.,Canales, A.,Steinmetz, M.O.,Diaz, J.F. Structural Basis of Noscapine Activation for Tubulin Binding. J.Med.Chem., 63:8495-8501, 2020 Cited by PubMed: 32657585 DOI: 10.1021/acs.jmedchem.0c00855 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation