1LNU
 
 | | CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IAb BOUND TO EALPHA3K PEPTIDE | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 class II histocompatibility antigen, A beta chain, ... | | 著者 | Liu, X, Dai, S, Crawford, F, Fruge, R, Marrack, P, Kappler, J. | | 登録日 | 2002-05-03 | | 公開日 | 2002-08-14 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Alternate interactions define the binding of peptides to the MHC molecule IA(b).
Proc.Natl.Acad.Sci.USA, 99, 2002
|
|
2PKY
 | | The Effect of Deuteration on Protein Structure A High Resolution Comparison of Hydrogenous and Perdeuterated Haloalkane Dehalogenase | | 分子名称: | Haloalkane dehalogenase | | 著者 | Liu, X, Hanson, L, Langan, P, Viola, R.E. | | 登録日 | 2007-04-18 | | 公開日 | 2007-09-04 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | The effect of deuteration on protein structure: a high-resolution comparison of hydrogenous and perdeuterated haloalkane dehalogenase.
Acta Crystallogr.,Sect.D, 63, 2007
|
|
3TGV
 | | Crystal structure of HutZ,the heme storsge protein from Vibrio cholerae | | 分子名称: | BENZOIC ACID, Heme-binding protein HutZ | | 著者 | Liu, X, Gong, J, Wang, Z, Du, Q, Wei, T, Zhu, D, Huang, Y, Xu, S, Gu, L. | | 登録日 | 2011-08-17 | | 公開日 | 2012-08-22 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | | 主引用文献 | Crystal structure of HutZ,the heme storsge protein from Vibrio cholerae
To be Published
|
|
4EEZ
 | | Crystal Structure of Lactococcus lactis Alcohol Dehydrogenase variant RE1 | | 分子名称: | Alcohol dehydrogenase 1, TETRAETHYLENE GLYCOL, ZINC ION | | 著者 | Liu, X, Bastian, S, Snow, C.D, Brustad, E.M, Saleski, T, Xu, J.H, Meinhold, P, Arnold, F.H. | | 登録日 | 2012-03-28 | | 公開日 | 2012-09-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-guided engineering of Lactococcus lactis alcohol dehydrogenase LlAdhA for improved conversion of isobutyraldehyde to isobutanol.
J.Biotechnol., 164, 2012
|
|
4EEX
 | | Crystal Structure of Lactococcus lactis Alcohol Dehydrogenase | | 分子名称: | Alcohol dehydrogenase 1, TETRAETHYLENE GLYCOL, ZINC ION | | 著者 | Liu, X, Bastian, S, Snow, C.D, Brustad, E.M, Saleski, T, Xu, J.H, Meinhold, P, Arnold, F.H. | | 登録日 | 2012-03-28 | | 公開日 | 2012-09-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure-guided engineering of Lactococcus lactis alcohol dehydrogenase LlAdhA for improved conversion of isobutyraldehyde to isobutanol.
J.Biotechnol., 164, 2012
|
|
6NWL
 | | Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with hydrocortisone and PGC1a coregulator fragment | | 分子名称: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... | | 著者 | Liu, X, Ortlund, E.A. | | 登録日 | 2019-02-06 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.595 Å) | | 主引用文献 | First High-Resolution Crystal Structures of the Glucocorticoid Receptor Ligand-Binding Domain-Peroxisome Proliferator-ActivatedgammaCoactivator 1-alphaComplex with Endogenous and Synthetic Glucocorticoids.
Mol.Pharmacol., 96, 2019
|
|
6NWK
 | |
7U1A
 | | RFC:PCNA bound to dsDNA with a ssDNA gap of six nucleotides | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA - Primer, DNA - Template, ... | | 著者 | Liu, X, Gaubitz, C, Pajak, J, Kelch, B.A. | | 登録日 | 2022-02-20 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA.
Elife, 11, 2022
|
|
7BQY
 | | THE CRYSTAL STRUCTURE OF COVID-19 MAIN PROTEASE IN COMPLEX WITH AN INHIBITOR N3 at 1.7 angstrom | | 分子名称: | 3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE | | 著者 | Liu, X, Zhang, B, Jin, Z, Yang, H, Rao, Z. | | 登録日 | 2020-03-26 | | 公開日 | 2020-04-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of Mprofrom SARS-CoV-2 and discovery of its inhibitors.
Nature, 582, 2020
|
|
4UEI
 | | Solution structure of the sterol carrier protein domain 2 of Helicoverpa armigera | | 分子名称: | STEROL CARRIER PROTEIN 2/3-OXOACYL-COA THIOLASE | | 著者 | Liu, X, Ma, H, Yan, X, Hong, H, Peng, J, Peng, R. | | 登録日 | 2014-12-18 | | 公開日 | 2015-12-30 | | 最終更新日 | 2019-10-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Structure and Function of Helicoverpa Armigera Sterol Carrier Protein-2, an Important Insecticidal Target from the Cotton Bollworm.
Sci.Rep., 5, 2015
|
|
6E67
 | | Structure of beta2 adrenergic receptor fused to a Gs peptide | | 分子名称: | 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Beta-2 adrenergic receptor,Endolysin,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Beta-2 adrenergic receptor chimera | | 著者 | Liu, X, Xu, X, Hilger, D, Tiemann, J, Liu, H, Du, Y, Hirata, K, Sun, X, Guixa-Gonzalez, R, Mathiesen, J, Hildebrand, P, Kobilka, B. | | 登録日 | 2018-07-24 | | 公開日 | 2019-06-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Structural Insights into the Process of GPCR-G Protein Complex Formation.
Cell, 177, 2019
|
|
8DQL
 | | CryoEM structure of IglD | | 分子名称: | Secretion system protein | | 著者 | Liu, X, Clemens, D, Lee, B, Yang, X, Zhou, H, Horwitz, M. | | 登録日 | 2022-07-19 | | 公開日 | 2022-08-17 | | 最終更新日 | 2022-11-09 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Atomic Structure of IglD Demonstrates Its Role as a Component of the Baseplate Complex of the Francisella Type VI Secretion System.
Mbio, 13, 2022
|
|
5MV2
 | | Crystal structure of the E protein of the Japanese encephalitis live attenuated vaccine virus | | 分子名称: | E protein | | 著者 | Liu, X, Zhao, X, Na, R, Li, L, Warkentin, E, Witt, J, Lu, X, Wei, Y, Peng, G, Li, Y, Wang, J. | | 登録日 | 2017-01-14 | | 公開日 | 2018-05-23 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The structure differences of Japanese encephalitis virus SA14 and SA14-14-2 E proteins elucidate the virulence attenuation mechanism.
Protein Cell, 10, 2019
|
|
3CI9
 | | Crystal Structure of the human HSBP1 | | 分子名称: | Heat shock factor-binding protein 1 | | 著者 | Liu, X, Xu, L, Liu, Y, Zhu, G, Zhang, X.C, Li, X, Rao, Z. | | 登録日 | 2008-03-11 | | 公開日 | 2009-01-20 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of the hexamer of human heat shock factor binding protein 1
Proteins, 75, 2009
|
|
5ZO1
 | | Crystal structure of mouse nectin-like molecule 4 (mNecl-4) full ectodomain (Ig1-Ig3), 2.2A | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Cell adhesion molecule 4, GLYCEROL | | 著者 | Liu, X, An, T, Li, D, Fan, Z, Xiang, P, Li, C, Ju, W, Li, J, Hu, G, Qin, B, Yin, B, Wojdyla, J.A, Wang, M, Yuan, J, Qiang, B, Shu, P, Cui, S, Peng, X. | | 登録日 | 2018-04-12 | | 公開日 | 2019-01-30 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Structure of the heterophilic interaction between the nectin-like 4 and nectin-like 1 molecules.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
|
|
6OBA
 | | The beta2 adrenergic receptor bound to a negative allosteric modulator | | 分子名称: | (2S)-1-[(1-methylethyl)amino]-3-(2-prop-2-en-1-ylphenoxy)propan-2-ol, 6-bromo-N~2~-phenylquinazoline-2,4-diamine, Beta-2 adrenergic receptor,Lysozyme,Beta-2 adrenergic receptor, ... | | 著者 | Liu, X, Stobel, A, Kaindl, J, Dengler, D, ClarK, M, Mahoney, J, Korczynska, M, Matt, R.A, Hubner, H, Xu, X, Stanek, M, Hirata, K, Shoichet, B, Sunahara, R, Gmeiner, R, Kobilka, B.K. | | 登録日 | 2019-03-20 | | 公開日 | 2020-03-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | An allosteric modulator binds to a conformational hub in the beta2adrenergic receptor.
Nat.Chem.Biol., 16, 2020
|
|
5MV1
 | | Crystal structure of the E protein of the Japanese encephalitis virulent virus | | 分子名称: | E protein | | 著者 | Liu, X, Zhao, X, Na, R, Li, L, Warkentin, E, Witt, J, Lu, X, Wei, Y, Peng, G, Li, Y, Wang, J. | | 登録日 | 2017-01-14 | | 公開日 | 2018-05-23 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | The structure differences of Japanese encephalitis virus SA14 and SA14-14-2 E proteins elucidate the virulence attenuation mechanism.
Protein Cell, 10, 2019
|
|
3QOF
 | |
3QNU
 | |
7MYN
 | | Cryo-EM Structure of p110alpha in complex with p85alpha | | 分子名称: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | | 著者 | Liu, X, Yang, S, Hart, J.R, Xu, Y, Zou, X, Zhang, H, Zhou, Q, Xia, T, Zhang, Y, Yang, D, Wang, M.-W, Vogt, P.K. | | 登録日 | 2021-05-21 | | 公開日 | 2021-11-10 | | 最終更新日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | | 主引用文献 | Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7MYO
 | | Cryo-EM structure of p110alpha in complex with p85alpha inhibited by BYL-719 | | 分子名称: | (2S)-N~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | | 著者 | Liu, X, Yang, S, Hart, J.R, Xu, Y, Zou, X, Zhang, H, Zhou, Q, Xia, T, Zhang, Y, Yang, D, Wang, M.-W, Vogt, P.K. | | 登録日 | 2021-05-21 | | 公開日 | 2021-11-10 | | 最終更新日 | 2021-11-24 | | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | | 主引用文献 | Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
2XD8
 | | Capsid structure of the infectious Prochlorococcus Cyanophage P-SSP7 | | 分子名称: | T7-LIKE CAPSID PROTEIN | | 著者 | Liu, X, Zhang, Q, Murata, K, Baker, M.L, Sullivan, M.B, Fu, C, Dougherty, M, Schmid, M.F, Osburne, M.S, Chisholm, S.W, Chiu, W. | | 登録日 | 2010-04-30 | | 公開日 | 2010-06-16 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structural Changes in a Marine Podovirus Associated with Release of its Genome Into Prochlorococcus
Nat.Struct.Mol.Biol., 17, 2010
|
|
2YXP
 | | The Effect of Deuteration on Protein Structure A High Resolution Comparison of Hydrogenous and Perdeuterated Haloalkane Dehalogenase | | 分子名称: | Haloalkane dehalogenase | | 著者 | Liu, X, Hanson, L, Langan, P, Viola, R.E. | | 登録日 | 2007-04-27 | | 公開日 | 2007-09-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | The effect of deuteration on protein structure: a high-resolution comparison of hydrogenous and perdeuterated haloalkane dehalogenase.
Acta Crystallogr.,Sect.D, 63, 2007
|
|
5HRC
 | | Crystal structure of an aspartate/glutamate racemase in complex with L-aspartate | | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ASPARTIC ACID, aspartate/glutamate racemase | | 著者 | Liu, X, Gao, F, Ma, Y, Liu, S, Cui, Y, Yuan, Z, Kang, X. | | 登録日 | 2016-01-23 | | 公開日 | 2016-04-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.765 Å) | | 主引用文献 | Crystal structure and molecular mechanism of an aspartate/glutamate racemase from Escherichia coli O157
Febs Lett., 590, 2016
|
|
5HRA
 | | Crystal structure of an aspartate/glutamate racemase in complex with D-aspartate | | 分子名称: | D-ASPARTIC ACID, aspartate/glutamate racemase | | 著者 | Liu, X, Gao, F, Ma, Y, Liu, S, Cui, Y, Yuan, Z, Kang, X. | | 登録日 | 2016-01-23 | | 公開日 | 2016-04-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.597 Å) | | 主引用文献 | Crystal structure and molecular mechanism of an aspartate/glutamate racemase from Escherichia coli O157
Febs Lett., 590, 2016
|
|
