4EEZ

Crystal Structure of Lactococcus lactis Alcohol Dehydrogenase variant RE1

Summary for 4EEZ

• Entry DOI: 10.2210/pdb4eez/pdb
• Related: 4EEX
• Descriptor: Alcohol dehydrogenase 1, ZINC ION, TETRAETHYLENE GLYCOL, ... (4 entities in total)
• Functional Keywords: alcohol dehydrogenase, site-saturation mutagenesis, directed evolution, isobutyraldehyde, biofuel, oxidoreductase
• Biological source: Lactococcus lactis subsp. lactis
• Total number of polymer chains: 2
• Total formula weight: 74142.16

Authors

Liu, X.,Bastian, S.,Snow, C.D.,Brustad, E.M.,Saleski, T.,Xu, J.H.,Meinhold, P.,Arnold, F.H. (deposition date: 2012-03-28, release date: 2012-09-26, Last modification date: 2024-02-28)

• Primary citation: Liu, X.,Bastian, S.,Snow, C.D.,Brustad, E.M.,Saleski, T.E.,Xu, J.H.,Meinhold, P.,Arnold, F.H.; Structure-guided engineering of Lactococcus lactis alcohol dehydrogenase LlAdhA for improved conversion of isobutyraldehyde to isobutanol.; J.Biotechnol., 164:188-195, 2012; PubMed: 22974724; DOI: 10.1016/j.jbiotec.2012.08.008

Experimental method

X-RAY DIFFRACTION (1.9 Å)