2KCL
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![BU of 2kcl by Molmil](/molmil-images/mine/2kcl) | Solution NMR structure of tetratricopeptide repeat domain protein SrU_0103 from Salinibacter ruber, Northeast Structural Genomics Consortium (NESG) Target SrR115C | Descriptor: | Tetratricopeptide repeat domain protein | Authors: | Liu, G, Rossi, P, Wang, D, Nwosu, C, Owens, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-12-22 | Release date: | 2009-01-06 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of tetratricopeptide repeat domain protein SrU_0103 from Salinibacter ruber, Northeast Structural Genomics Consortium (NESG) Target SrR115C To be Published
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3ELO
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![BU of 3elo by Molmil](/molmil-images/mine/3elo) | Crystal Structure of Human Pancreatic Prophospholipase A2 | Descriptor: | Phospholipase A2, SULFATE ION | Authors: | Xu, W, Yi, L, Feng, Y, Chen, L, Liu, J. | Deposit date: | 2008-09-22 | Release date: | 2009-04-14 | Last modified: | 2014-02-05 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural insight into the activation mechanism of human pancreatic prophospholipase A2 J.Biol.Chem., 284, 2009
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2HH8
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![BU of 2hh8 by Molmil](/molmil-images/mine/2hh8) | Solution NMR structure of the ydfO protein from Escherichia coli. Northeast Structural Genomics target ER251. | Descriptor: | Hypothetical protein ydfO | Authors: | Rossi, P, Cort, J.R, Ho, C.K, Janjua, H, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M, Swapna, G.V.T, Acton, T.B, Rost, B, Kennedy, M.A, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-06-28 | Release date: | 2006-08-22 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of the ydfO protein from Escherichia coli. Northeast Structural Genomics target ER251. To be Published
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2HGC
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![BU of 2hgc by Molmil](/molmil-images/mine/2hgc) | Solution NMR structure of the YjcQ protein from Bacillus subtilis. Northeast Structural Genomics target SR346. | Descriptor: | YjcQ protein | Authors: | Rossi, P, Cort, J.R, Ho, C.K, Janjua, H, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M, Swapna, G.V.T, Acton, T.B, Rost, B, Kennedy, M.A, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-06-26 | Release date: | 2006-08-22 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of the YjcQ protein from Bacillus subtilis. Northeast Structural Genomics target SR346. (CASP Target) To be Published
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2HJ0
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![BU of 2hj0 by Molmil](/molmil-images/mine/2hj0) | Crystal Structure of the Putative Alfa Subunit of Citrate Lyase in Complex with Citrate from Streptococcus mutans, Northeast Structural Genomics Target SmR12 . | Descriptor: | CITRIC ACID, Putative citrate lyase, alfa subunit | Authors: | Forouhar, F, Hussain, M, Jayaraman, S, Shastry, R, Janjua, H, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-06-29 | Release date: | 2006-08-29 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of the Putative Alfa Subunit of Citrate Lyase in Complex with Citrate from Streptococcus mutans, Northeast Structural Genomics Target SmR12 (CASP Target). To be Published
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2DSM
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![BU of 2dsm by Molmil](/molmil-images/mine/2dsm) | NMR Structure of Bacillus Subtilis Protein YqaI, Northeast Structural Genomics Target SR450 | Descriptor: | Hypothetical protein yqaI | Authors: | Ramelot, T.A, Cort, J.R, Wang, D, Janua, H, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-07-01 | Release date: | 2006-08-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR Structure of Bacillus Subtilis Protein YqaI, Northeast Structural Genomics Target SR450 to be published
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2HJJ
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![BU of 2hjj by Molmil](/molmil-images/mine/2hjj) | Solution NMR structure of protein ykfF from Escherichia coli. Northeast Structural Genomics target ER397. | Descriptor: | Hypothetical protein ykfF | Authors: | Swapna, G.V.T, Aramini, J.M, Zhao, L, Cunningham, K, Janjua, H, Ma, L.-C, Xiao, R, Baran, M.C, Acton, T.B, Liu, J, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-06-30 | Release date: | 2006-08-29 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of protein ykfF from Escherichia coli. Northeast Structural Genomics target ER397. To be Published
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2HRX
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![BU of 2hrx by Molmil](/molmil-images/mine/2hrx) | X-Ray Crystal Structure of Protein DIP2367 from Corynebacterium diphtheriae. Northeast Structural Genomics Consortium Target CdR13. | Descriptor: | Hypothetical protein | Authors: | Kuzin, A.P, Su, M, Jayaraman, S, Ho, C.K, Janjua, H, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-07-20 | Release date: | 2006-08-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Three dimensional structure of conserved hypothetical protein from Corynebacterium diphtheriae at the resolution 1.9 A. Northeast Structural Genomics Consortium target CdR13. TO BE PUBLISHED
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7WKJ
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![BU of 7wkj by Molmil](/molmil-images/mine/7wkj) | A COVID-19 T-cell response detection method based on a newly identified human CD8+ T cell epitope from SARS-CoV-2-Hubei Province, 2021. | Descriptor: | Beta-2-microglobulin, LYS-THR-PHE-PRO-PRO-THR-GLU-PRO-LYS, MHC class I antigen | Authors: | Zhang, J, Lu, D, Li, M, Liu, M.S, Yao, S.J, Zhan, J.B, Liu, J, Gao, G.F. | Deposit date: | 2022-01-10 | Release date: | 2022-03-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A COVID-19 T-Cell Response Detection Method Based on a Newly Identified Human CD8 + T Cell Epitope from SARS-CoV-2 - Hubei Province, China, 2021. China CDC Wkly, 4, 2022
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8I0I
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![BU of 8i0i by Molmil](/molmil-images/mine/8i0i) | dmCTPS with dATP dUTP dGTP and DON | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CTP synthase, DEOXYURIDINE-5'-TRIPHOSPHATE, ... | Authors: | Guo, C.J, Liu, J.L. | Deposit date: | 2023-01-11 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of bifunctional CTP/dCTP synthase Biorxiv, 2023
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4HXX
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![BU of 4hxx by Molmil](/molmil-images/mine/4hxx) | Pyridinylpyrimidines selectively inhibit human methionine aminopeptidase-1 | Descriptor: | (1R)-N~2~-[5-chloro-2-(5-chloropyridin-2-yl)-6-methylpyrimidin-4-yl]-1-phenyl-N~1~-(4-phenylbutyl)ethane-1,2-diamine, COBALT (II) ION, Methionine aminopeptidase 1, ... | Authors: | Gabelli, S.B, Zhang, F, Liu, J, Amzel, L.M. | Deposit date: | 2012-11-12 | Release date: | 2013-04-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Pyridinylpyrimidines selectively inhibit human methionine aminopeptidase-1. Bioorg.Med.Chem., 21, 2013
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6JUI
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![BU of 6jui by Molmil](/molmil-images/mine/6jui) | The atypical Myb-like protein Cdc5 contains two distinct nucleic acid-binding surfaces | Descriptor: | Pre-mRNA-splicing factor CEF1 | Authors: | Wang, C, Li, G, Li, M, Yang, J, Liu, J. | Deposit date: | 2019-04-14 | Release date: | 2020-02-19 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.402 Å) | Cite: | Two distinct nucleic acid binding surfaces of Cdc5 regulate development. Biochem.J., 476, 2019
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8J0F
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![BU of 8j0f by Molmil](/molmil-images/mine/8j0f) | GK tetramer with adjacent hooks at reaction state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Delta-1-pyrroline-5-carboxylate synthase B, GAMMA-GLUTAMYL PHOSPHATE, ... | Authors: | Zhang, T, Guo, C.J, Liu, J.L. | Deposit date: | 2023-04-10 | Release date: | 2024-04-17 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Dynamic Arabidopsis P5CS filament facilitates substrate channelling. Nat.Plants, 10, 2024
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8VH8
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![BU of 8vh8 by Molmil](/molmil-images/mine/8vh8) | Crystal structure of heparosan synthase 2 from Pasteurella multocida at 2.85 A | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Pedersen, L.C, Liu, J, Stancanelli, E, krahn, J.M. | Deposit date: | 2023-12-31 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural and Functional Analysis of Heparosan Synthase 2 from Pasteurella multocida to Improve the Synthesis of Heparin Acs Catalysis, 14, 2024
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6JC7
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![BU of 6jc7 by Molmil](/molmil-images/mine/6jc7) | Crystal structure of aminotransferase CrmG from Actinoalloteichus sp. WH1-2216-6 in complex with amino donor L-Ala | Descriptor: | (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-alanine, ACETIC ACID, CrmG, ... | Authors: | Xu, J, Su, K, Liu, J. | Deposit date: | 2019-01-28 | Release date: | 2020-02-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural studies reveal flexible roof of active site responsible for omega-transaminase CrmG overcoming by-product inhibition. Commun Biol, 3, 2020
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8HAY
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![BU of 8hay by Molmil](/molmil-images/mine/8hay) | d4-bound btDPP4 | Descriptor: | (1~{R})-1-[[4-[5-[[(1~{R})-6,7-dimethoxy-2-methyl-3,4-dihydro-1~{H}-isoquinolin-1-yl]methyl]-2-methoxy-phenoxy]phenyl]methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1~{H}-isoquinoline, btDPP4 | Authors: | Hang, J, Jiang, C, Wang, K, Zhang, Z, Guo, F, Liu, J, Wang, G, Lei, X, Gonzalez, F, Qiao, J. | Deposit date: | 2022-10-27 | Release date: | 2023-07-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | Microbial-host-isozyme analyses reveal microbial DPP4 as a potential antidiabetic target. Science, 381, 2023
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8VH7
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![BU of 8vh7 by Molmil](/molmil-images/mine/8vh7) | Crystal structure of heparosan synthase 2 from Pasteurella multocida at 1.98 A | Descriptor: | 1,2-ETHANEDIOL, Heparosan synthase B, MANGANESE (II) ION, ... | Authors: | Pedersen, L.C, Liu, J, Stancanelli, E, Krahn, J.M. | Deposit date: | 2023-12-31 | Release date: | 2024-07-24 | Method: | X-RAY DIFFRACTION (1.982 Å) | Cite: | Structural and Functional Analysis of Heparosan Synthase 2 from Pasteurella multocida to Improve the Synthesis of Heparin Acs Catalysis, 14, 2024
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8VIW
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![BU of 8viw by Molmil](/molmil-images/mine/8viw) | Cryo-EM structure of heparosan synthase 2 from Pasteurella multocida with polysaccharide in the GlcNAc-T active site | Descriptor: | Heparosan synthase B, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ... | Authors: | Krahn, J.M, Pedersen, L.C, Liu, J, Stancanelli, E, Borgnia, M, Vivarette, E. | Deposit date: | 2024-01-05 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural and Functional Analysis of Heparosan Synthase 2 from Pasteurella multocida to Improve the Synthesis of Heparin Acs Catalysis, 14, 2024
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6JC9
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![BU of 6jc9 by Molmil](/molmil-images/mine/6jc9) | |
5H6B
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![BU of 5h6b by Molmil](/molmil-images/mine/5h6b) | Crystal structure of a thermostable lipase from Marine Streptomyces | Descriptor: | ACETATE ION, IMIDAZOLE, Putative secreted lipase, ... | Authors: | Hou, S, Zhao, Z, Liu, J. | Deposit date: | 2016-11-11 | Release date: | 2017-09-20 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of a lipase from Streptomyces sp. strain W007 - implications for thermostability and regiospecificity FEBS J., 284, 2017
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5DUO
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![BU of 5duo by Molmil](/molmil-images/mine/5duo) | Crystal structure of native translocator protein 18kDa (TSPO) from Rhodobacter sphaeroides (A139T Mutant) in C2 space group | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, FORMIC ACID, PROTOPORPHYRIN IX, ... | Authors: | Li, F, Liu, J, Zheng, Y, Garavito, R.M, Ferguson-Miller, S. | Deposit date: | 2015-09-20 | Release date: | 2015-11-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Response to Comment on "Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism". Science, 350, 2015
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6JAK
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![BU of 6jak by Molmil](/molmil-images/mine/6jak) | OtsA apo structure | Descriptor: | Trehalose-6-phosphate synthase | Authors: | Wang, S, Zhao, Y, Wang, D, Liu, J. | Deposit date: | 2019-01-24 | Release date: | 2019-12-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Crystal structures of Magnaporthe oryzae trehalose-6-phosphate synthase (MoTps1) suggest a model for catalytic process of Tps1. Biochem.J., 476, 2019
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6JBI
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![BU of 6jbi by Molmil](/molmil-images/mine/6jbi) | Structure of Tps1 apo structure | Descriptor: | Trehalose-6-phosphate synthase | Authors: | Wang, S, Zhao, Y, Yi, L, Wang, D, Liu, J. | Deposit date: | 2019-01-25 | Release date: | 2019-12-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of Magnaporthe oryzae trehalose-6-phosphate synthase (MoTps1) suggest a model for catalytic process of Tps1. Biochem.J., 476, 2019
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6JCA
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![BU of 6jca by Molmil](/molmil-images/mine/6jca) | |
6JC8
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![BU of 6jc8 by Molmil](/molmil-images/mine/6jc8) | |