7WKJ

A COVID-19 T-cell response detection method based on a newly identified human CD8+ T cell epitope from SARS-CoV-2-Hubei Province, 2021.

Summary for 7WKJ

• Entry DOI: 10.2210/pdb7wkj/pdb
• Descriptor: MHC class I antigen, Beta-2-microglobulin, LYS-THR-PHE-PRO-PRO-THR-GLU-PRO-LYS, ... (4 entities in total)
• Functional Keywords: hla-a*1101-n25 complex; sars-cov-2;, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 44520.31

Authors

Zhang, J.,Lu, D.,Li, M.,Liu, M.S.,Yao, S.J.,Zhan, J.B.,Liu, J.,Gao, G.F. (deposition date: 2022-01-10, release date: 2022-03-02, Last modification date: 2024-10-23)

Primary citation

Zhang, J.,Lu, D.,Li, M.,Liu, M.,Yao, S.,Zhan, J.,Liu, W.J.,Gao, G.F.
A COVID-19 T-Cell Response Detection Method Based on a Newly Identified Human CD8 + T Cell Epitope from SARS-CoV-2 - Hubei Province, China, 2021.
China CDC Wkly, 4:83-87, 2022

PubMed Abstract: Similar to antibody detection, severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2)-specific T-cell response evaluation is also pivotal among the coronavirus disease 2019 (COVID-19) convalescents and the vaccinated populations. Nucleocapsid (N) protein is one of the main structural proteins of SARS-CoV-2 and can trigger T-cell responses in humans.

PubMed: 35186375
DOI: 10.46234/ccdcw2021.258

Experimental method

X-RAY DIFFRACTION (1.5 Å)