5DUO

Crystal structure of native translocator protein 18kDa (TSPO) from Rhodobacter sphaeroides (A139T Mutant) in C2 space group

Summary for 5DUO

• Entry DOI: 10.2210/pdb5duo/pdb
• Related: 4UC1
• Descriptor: Tryptophan-rich sensory protein, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, FORMIC ACID, ... (5 entities in total)
• Functional Keywords: mitochondria, transport, 5 transmembrane helices, membrane protein
• Biological source: Rhodobacter sphaeroides
• Total number of polymer chains: 3
• Total formula weight: 59834.77

Authors

Li, F.,Liu, J.,Zheng, Y.,Garavito, R.M.,Ferguson-Miller, S. (deposition date: 2015-09-20, release date: 2015-11-11, Last modification date: 2024-03-06)

Primary citation

Li, F.,Liu, J.,Zheng, Y.,Garavito, R.M.,Ferguson-Miller, S.
Response to Comment on "Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism".
Science, 350:519-519, 2015

PubMed Abstract: Wang comments that the diffraction data for the structure of the A139T mutant of translocator protein TSPO from Rhodobacter sphaeroides should be used to 1.65 instead of 1.8 angstroms and that the density interpreted as porphyrin and monoolein is better fitted as polyethylene glycol. Although different practices of data processing exist, in this case they do not substantially influence the final map. Additional data are presented supporting the fit of a porphyrin and monooleins.

PubMed: 26516277
DOI: 10.1126/science.aab2595

Experimental method

X-RAY DIFFRACTION (2.4 Å)