4IHA
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![BU of 4iha by Molmil](/molmil-images/mine/4iha) | Crystal structure of rice DWARF14 (D14) in complex with a GR24 hydrolysis intermediate | Descriptor: | (2R,3R)-2,4,4-trihydroxy-3-methylbutanal, Dwarf 88 esterase | Authors: | Zhou, X.E, Zhao, L.-H, Wu, Z.-S, Yi, W, Li, S, Li, Y, Xu, Y, Xu, T.-H, Liu, Y, Chen, R.-Z, Kovach, A, Kang, Y, Hou, L, He, Y, Zhang, C, Melcher, K, Xu, H.E. | Deposit date: | 2012-12-18 | Release date: | 2013-01-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14. Cell Res., 23, 2013
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6XZ7
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![BU of 6xz7 by Molmil](/molmil-images/mine/6xz7) | E. coli 50S ribosomal subunit in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet). | Descriptor: | 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | Authors: | Pichkur, E.B, Polikanov, Y.S, Myasnikov, A.G, Konevega, A.L. | Deposit date: | 2020-02-03 | Release date: | 2020-07-22 | Method: | ELECTRON MICROSCOPY (2.1 Å) | Cite: | Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to theE. coli70S ribosome. Rna, 26, 2020
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6XZA
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![BU of 6xza by Molmil](/molmil-images/mine/6xza) | E. coli 70S ribosome in complex with dirithromycin, and deacylated tRNA(iMet) (focused classification). | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Pichkur, E.B, Polikanov, Y.S, Myasnikov, A.G, Konevega, A.L. | Deposit date: | 2020-02-03 | Release date: | 2020-11-04 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to the E. coli 70S ribosome. Rna, 26, 2020
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6XZB
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![BU of 6xzb by Molmil](/molmil-images/mine/6xzb) | E. coli 70S ribosome in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet) (focused classification). | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Pichkur, E.B, Polikanov, Y.S, Myasnikov, A.G, Konevega, A.L. | Deposit date: | 2020-02-03 | Release date: | 2020-11-04 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.54 Å) | Cite: | Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to the E. coli 70S ribosome. Rna, 26, 2020
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5TDH
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![BU of 5tdh by Molmil](/molmil-images/mine/5tdh) | The crystal structure of the dominant negative mutant G protein alpha(i)-1-beta-1-gamma-2 G203A/A326S | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Liu, P, Jia, M.-Z, Zhou, X.E, de Waal, P.W, Dickson, B.M, Liu, B, Hou, L, Yin, Y.-T, Kang, Y.-Y, Shi, Y, Melcher, K, Xu, H.E, Jiang, Y. | Deposit date: | 2016-09-19 | Release date: | 2016-11-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The structural basis of the dominant negative phenotype of the G alpha i1 beta 1 gamma 2 G203A/A326S heterotrimer Acta Pharmacol.Sin., 37, 2016
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3AN2
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![BU of 3an2 by Molmil](/molmil-images/mine/3an2) | The structure of the centromeric nucleosome containing CENP-A | Descriptor: | 147 mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Tachiwana, H, Kagawa, W, Shiga, T, Saito, K, Osakabe, A, Hayashi-Takanaka, Y, Park, S.-Y, Kimura, H, Kurumizaka, H. | Deposit date: | 2010-08-27 | Release date: | 2011-07-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Crystal structure of the human centromeric nucleosome containing CENP-A Nature, 476, 2011
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3ABG
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![BU of 3abg by Molmil](/molmil-images/mine/3abg) | X-ray Crystal Analysis of Bilirubin Oxidase from Myrothecium verrucaria at 2.3 angstrom Resolution using a Twin Crystal | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Bilirubin oxidase, COPPER (II) ION, ... | Authors: | Mizutani, K, Toyoda, M, Sagara, K, Takahashi, N, Sato, A, Kamitaka, Y, Tsujimura, S, Nakanishi, Y, Sugiura, T, Yamaguchi, S, Kano, K, Mikami, B. | Deposit date: | 2009-12-10 | Release date: | 2010-08-18 | Last modified: | 2023-07-26 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | X-ray analysis of bilirubin oxidase from Myrothecium verrucaria at 2.3 A resolution using a twinned crystal Acta Crystallogr.,Sect.F, 66, 2010
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5J4C
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![BU of 5j4c by Molmil](/molmil-images/mine/5j4c) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with cisplatin (soaked) and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Melnikov, S.V, Soll, D, Steitz, T.A, Polikanov, Y.S. | Deposit date: | 2016-03-31 | Release date: | 2016-04-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome. Nucleic Acids Res., 44, 2016
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2ZOC
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![BU of 2zoc by Molmil](/molmil-images/mine/2zoc) | Crystal structure of recombinant human annexin IV | Descriptor: | Annexin A4, CALCIUM ION | Authors: | Konno, M, Kaneko-Kanzaki, Y, Fushinobu-Okushi, N, Mochizuki, K, Uchikaw, E, Satoh, A, Aikawa, K. | Deposit date: | 2008-05-08 | Release date: | 2009-04-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The comparison of the loop structure of membrane binding sites between human and bovine annexin IV To be Published
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3AQG
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![BU of 3aqg by Molmil](/molmil-images/mine/3aqg) | Crystal structure of human pancreatic secretory protein ZG16b | Descriptor: | PHOSPHATE ION, Zymogen granule protein 16 homolog B | Authors: | Kanagawa, M, Satoh, T, Nakano, Y, Kojima-Aikawa, K, Yamaguchi, Y. | Deposit date: | 2010-11-01 | Release date: | 2010-12-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structures of human secretory proteins ZG16p and ZG16b reveal a Jacalin-related beta-prism fold Biochem.Biophys.Res.Commun., 2010
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6UO1
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![BU of 6uo1 by Molmil](/molmil-images/mine/6uo1) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA (containing pseudouridine at the first position of the codon) and deacylated A-, P-, and E-site tRNAs at 2.95A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Batool, Z, Dobosz-Bartoszek, M, Polikanov, Y.S. | Deposit date: | 2019-10-14 | Release date: | 2019-11-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Pseudouridinylation of mRNA coding sequences alters translation. Proc.Natl.Acad.Sci.USA, 116, 2019
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6N9F
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![BU of 6n9f by Molmil](/molmil-images/mine/6n9f) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with a short substrate mimic ACCA-DPhe and bound to mRNA and P-site tRNA at 3.7A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S19, ... | Authors: | Melnikov, S.V, Khabibullina, N.F, Mairhofer, E, Vargas-Rodriguez, O, Reynolds, N.M, Micura, R, Soll, D, Polikanov, Y.S. | Deposit date: | 2018-12-03 | Release date: | 2018-12-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site. Nucleic Acids Res., 47, 2019
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6N9E
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![BU of 6n9e by Molmil](/molmil-images/mine/6n9e) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with a short substrate mimic CC-Pmn and bound to mRNA and P-site tRNA at 3.7A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S19, ... | Authors: | Melnikov, S.V, Khabibullina, N.F, Mairhofer, E, Vargas-Rodriguez, O, Reynolds, N.M, Micura, R, Soll, D, Polikanov, Y.S. | Deposit date: | 2018-12-03 | Release date: | 2018-12-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site. Nucleic Acids Res., 47, 2019
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6ND5
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![BU of 6nd5 by Molmil](/molmil-images/mine/6nd5) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with chloramphenicol and bound to mRNA and A-, P-, and E-site tRNAs at 2.60A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Svetlov, M.S, Plessa, E, Chen, C.-W, Bougas, A, Krokidis, M.G, Dinos, G.P, Polikanov, Y.S. | Deposit date: | 2018-12-13 | Release date: | 2019-03-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition. RNA, 25, 2019
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3K7G
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![BU of 3k7g by Molmil](/molmil-images/mine/3k7g) | Crystal structure of the Indian Hedgehog N-terminal signalling domain | Descriptor: | GLYCEROL, Indian hedgehog protein, SULFATE ION, ... | Authors: | He, Y.-X, Kang, Y, Zhang, W.J, Yu, J, Ma, G, Zhou, C.-Z. | Deposit date: | 2009-10-13 | Release date: | 2011-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of the Indian Hedgehog N-terminal signalling domain To be Published
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5J4B
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![BU of 5j4b by Molmil](/molmil-images/mine/5j4b) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with cisplatin (co-crystallized) and bound to mRNA and A-, P- and E-site tRNAs at 2.6A resolution | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Melnikov, S.V, Soll, D, Steitz, T.A, Polikanov, Y.S. | Deposit date: | 2016-03-31 | Release date: | 2016-04-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome. Nucleic Acids Res., 44, 2016
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6ND6
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![BU of 6nd6 by Molmil](/molmil-images/mine/6nd6) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with erythromycin and bound to mRNA and A-, P-, and E-site tRNAs at 2.85A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Svetlov, M.S, Plessa, E, Chen, C.-W, Bougas, A, Krokidis, M.G, Dinos, G.P, Polikanov, Y.S. | Deposit date: | 2018-12-13 | Release date: | 2019-02-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition. RNA, 25, 2019
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3K7I
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![BU of 3k7i by Molmil](/molmil-images/mine/3k7i) | Crystal structure of the E131K mutant of the Indian Hedgehog N-terminal signalling domain | Descriptor: | Indian hedgehog protein, SULFATE ION, ZINC ION | Authors: | He, Y.-X, Kang, Y, Zhang, W.J, Yu, J, Ma, G, Zhou, C.-Z. | Deposit date: | 2009-10-13 | Release date: | 2011-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.438 Å) | Cite: | Crystal structure of the E131K mutant of the Indian Hedgehog N-terminal signalling domain To be Published
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3K7H
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![BU of 3k7h by Molmil](/molmil-images/mine/3k7h) | Crystal structure of the E95K mutant of the Indian Hedgehog N-terminal signalling domain | Descriptor: | Indian hedgehog protein, SULFATE ION, ZINC ION | Authors: | He, Y.-X, Kang, Y, Zhang, W.J, Yu, J, Ma, G, Zhou, C.-Z. | Deposit date: | 2009-10-13 | Release date: | 2011-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of the E95K mutant of the Indian Hedgehog N-terminal signalling domain To be Published
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3K7J
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![BU of 3k7j by Molmil](/molmil-images/mine/3k7j) | Crystal structure of the D100E mutant of the Indian Hedgehog N-terminal signalling domain | Descriptor: | CARBONATE ION, Indian hedgehog protein, SULFATE ION, ... | Authors: | He, Y.-X, Kang, Y, Zhang, W.J, Yu, J, Ma, G, Zhou, C.-Z. | Deposit date: | 2009-10-13 | Release date: | 2011-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the D100E mutant of the Indian Hedgehog N-terminal signalling domain To be Published
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6CFL
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![BU of 6cfl by Molmil](/molmil-images/mine/6cfl) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with lysyl-CAM and bound to protein Y (YfiA) at 2.6A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Tereshchenkov, A.G, Dobosz-Bartoszek, M, Osterman, I.A, Marks, J, Sergeeva, V.A, Kasatsky, P, Komarova, E.S, Stavrianidi, A.N, Rodin, I.A, Konevega, A.L, Sergiev, P.V, Sumbatyan, N.V, Mankin, A.S, Bogdanov, A.A, Polikanov, Y.S. | Deposit date: | 2018-02-15 | Release date: | 2018-03-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Binding and Action of Amino Acid Analogs of Chloramphenicol upon the Bacterial Ribosome. J. Mol. Biol., 430, 2018
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6CFK
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![BU of 6cfk by Molmil](/molmil-images/mine/6cfk) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with D-histidyl-CAM and bound to protein Y (YfiA) at 2.7A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Tereshchenkov, A.G, Dobosz-Bartoszek, M, Osterman, I.A, Marks, J, Sergeeva, V.A, Kasatsky, P, Komarova, E.S, Stavrianidi, A.N, Rodin, I.A, Konevega, A.L, Sergiev, P.V, Sumbatyan, N.V, Mankin, A.S, Bogdanov, A.A, Polikanov, Y.S. | Deposit date: | 2018-02-15 | Release date: | 2018-03-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Binding and Action of Amino Acid Analogs of Chloramphenicol upon the Bacterial Ribosome. J. Mol. Biol., 430, 2018
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3APA
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![BU of 3apa by Molmil](/molmil-images/mine/3apa) | Crystal structure of human pancreatic secretory protein ZG16p | Descriptor: | CHLORIDE ION, GLYCEROL, Zymogen granule membrane protein 16 | Authors: | Kanagawa, M, Satoh, T, Nakano, Y, Kojima-Aikawa, K, Yamaguchi, Y. | Deposit date: | 2010-10-13 | Release date: | 2010-12-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structures of human secretory proteins ZG16p and ZG16b reveal a Jacalin-related beta-prism fold Biochem.Biophys.Res.Commun., 2010
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8HBW
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![BU of 8hbw by Molmil](/molmil-images/mine/8hbw) | Structure of human UCP1 in the ATP-bound state | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-TRIPHOSPHATE, CARDIOLIPIN, ... | Authors: | Chen, L, Kang, Y. | Deposit date: | 2022-10-31 | Release date: | 2023-06-21 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | Structural basis for the binding of DNP and purine nucleotides onto UCP1. Nature, 620, 2023
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8HBV
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![BU of 8hbv by Molmil](/molmil-images/mine/8hbv) | Structure of human UCP1 in the nucleotide-free state | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CARDIOLIPIN, Mitochondrial brown fat uncoupling protein 1, ... | Authors: | Chen, L, Kang, Y. | Deposit date: | 2022-10-31 | Release date: | 2023-06-21 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (2.51 Å) | Cite: | Structural basis for the binding of DNP and purine nucleotides onto UCP1. Nature, 620, 2023
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